On Oct 19, 2020, at 2:38 AM, 李梦君 <mengjun@csu.edu.cn> wrote:

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Dear FreeSurfer Developers:

  My name is Mengjun Li, I am a MD in the Second Xiangya Hospital, Central South University. I compared the cortex, area, volume in the mild traumatic brain injury patients with health control by the FreeSurFer and found the problem when mapping label to the single subjects.

  There is statistic difference in the area and volume between the mild traumatic brain injury patients and the health control, I defined the statistic difference region as a label on the fsaverage and mapped this label to subjects by the Qdec. Although the label defined on the fsaverage was mapped onto all subjects successfully,the label in the subjects did not match well with the inflated cortex of the subjects. At the same time, the volume and area value of the label have been extracted in every subject and I found that there is no statistic difference between the mild traumatic brain injury patients and health control. I have checked the segmentation of every subjects and it was a good job done by FreeSurFer. Attached figures illustrated the label mapping results.

Figure 1: the label defined on the fsaverage

Figure 2: the lateral view of the label in the subjects

Figure 3: the inferior view of the label in the subjects

FreeSurfer version: freesurfer-Darwin-OSX-stable-pub-v6.0.0-2beb96c

Platform: macOS High Sierra

  I am sending this email for help since I am not sure how to fix this problem. Looking forward to hearing your reply! Thank you very much!

Best wishes

Mengjun Li

Second Xiangya Hospital 

Central South University.

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