Hello, FreeSurfer group,

When I ran glmfit I got the following error massage. I standardize ages but the problem remains. Any other suggestions? Alternatively, is there any way to by-pass this design checking step?

Thank you very much.

Xin

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ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08

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Possible problem with experimental design:

Check for duplicate entries and/or lack of range of

continuous variables within a class.

If you seek help with this problem, make sure to send:

  1. Your command line:

    mri_glmfit.bin --y RESULT/group_currPTSD_AgeGenderSiteFACT_adult/lh_group_currPTSD_AgeGenderSiteFACT_adult.fwhm10.fsaverage.mgh --fsgd group_currPTSD_AgeGenderSiteFACT_adult.fsgd dods --glmdir RESULT/group_currPTSD_AgeGenderSiteFACT_adult/lh --surf fsaverage/ lh --C group_currPTSD_AgeGenderSiteFACT_adult.mtx

  2. The FSGD file (if using one)

  3. And the design matrix above

Attempting to diagnose further

SumSq: Min=0.330000 (col 38), Max=18.703472 (col 62)

The scale is much different between columns 38 and 62, you may want to

 normalize by subtracting the mean and dividing by the standard deviation.

ERROR: cannot find RESULT/group_currPTSD_AgeGenderSiteFACT_adult/lh/fwhm.dat