Hi Dr Yendiki, I am studying a group of people with APOE4 and I want to see whether cortical MD increases can be detected relative to non-carriers, and if so, is the effect size bigger than changes in cortical thickness.
On Friday, August 11, 2017, 11:19:32 AM GMT+1, Yendiki, Anastasia <AYENDIKI@mgh.harvard.edu> wrote:
What effect are you trying to measure with MD on the cortex?
From: Shane Schofield [shane.schofield@yahoo.com] Sent: Friday, August 11, 2017 3:12 AM To: Freesurfer Support List; Yendiki, Anastasia Subject: Re: Mean diffusivity on cortex?
Thanks Dr Yendiki.
I am more interested to compare MD in grey matter regions by putting the MD on the surface, and then do a glmfit type of comparisons. Is that OK? Would you recommend me to smooth the data after spatial normalisation? I have also used the mri_cvs_register
as described on the tutorial.
On Friday, August 11, 2017, 7:03:49 AM GMT+1, Shane Schofield <shane.schofield@yahoo.com> wrote:
Hi DTI Experts,
Is it sensible to do comparisons of MD on the cortex surface like a normal cortical thickness comparisons between group? If the answer is yes, are there recommended on smoothing ?
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