Hi,<br><br>this link:<br><a href="http://surfer.nmr.mgh.harvard.edu/fswiki/TalFailV5.1">http://surfer.nmr.mgh.harvard.edu/fswiki/TalFailV5.1</a><br>discusses a solution to bad talairach.xfm transforms, the -use-mritotal flag.<br>
<br>this link:<br><a href="http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV">http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV</a><br>mentions that the talairach.xfm is used to calculate the total intracranial volume.<br><br>is using mritotal likely to result in significantly different intracranial volumes even if the talairach.xfm does not appear to be very different when viewed?<br>
<br>thanks much,<br>-eric<br><br><br>