Dear FreeSurfer,

I am trying to compare my subjects to the healthy group, but when I put the matrix into qdec, I get the following error:

Normalized matrix condition is 1e+08
Design matrix ------------------
 1.000   0.000   0.000   0.000   68.000   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   66.000   0.000;
 1.000   0.000   0.000   0.000   40.000   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   35.000   0.000;
 1.000   0.000   0.000   0.000   72.000   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   71.000   0.000;
 1.000   0.000   0.000   0.000   22.000   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   22.000   0.000;
 0.000   1.000   0.000   0.000   0.000   20.000   0.000   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   20.000;
--------------------------------
ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08


  1. Your command line:
    mri_glmfit --y /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/y.mgh --fsgd /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/qdec.fsgd dods --glmdir /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled --surf fsaverage lh --label /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/fsaverage/label/lh.aparc.label --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Avg-thickness-age-Cor.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-Male-Female-Intercept-thickness.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-Male-Female-Cor-thickness-age.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-spelling-healthy-Intercept-thickness.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-spelling-healthy-Cor-thickness-age.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-X-gender2-diagnosis_spelling-Intercept-thickness.mat --C /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-X-gender2-diagnosis_spelling-Cor-thickness-age.mat 



the table file is also attached to the mail.

Would you please kindly guide me with this?

Best Regards,
Mahtab.