So what I understand is that we can do the segmentation using the whole brain MRI and then use the higher contrast MRI to refine the thalamus segmentation? if so, can you explain more about it?

Thank you

Dorsa

On Thu, Oct 20, 2016 at 12:20 PM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
no, you need full brain coverage in at least one, but we do have some prototype tools that use a smaller FOV image after a recon to segment specific structures (including at least a bit of work on the STN).

As I said though, depending on the details of the 40 slice image I would be cautious about using it as a gold-standard to interpret the T1. I would need more information to say for sure



On Thu, 20 Oct 2016, Dorsa Haji Ghaffari wrote:

So basically we have two types of images. One has a better contrast for seeing the STN to that we can target it for deep brain
stimulation, but that one is only 40 slices and is not the whole brain. We have another set of images which is complete but does
not have a good contrast for showing the sub-cortical structures. I have attached a sample of each one. I have also attached my
subject. Does Freesurfer work with only 40 slices?

On Thu, Oct 20, 2016 at 9:51 AM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
      Hi Dorsa

      if you upload your subject I'll take a look. What is a 3TC image? I don't know what contrast the image you sent is
      but I would be cautious about only using it to assess the accuracy of the T1 segmentation

      cheers
      Bruce

      On Wed, 19 Oct 2016, Dorsa Haji Ghaffari wrote:

            I have attached a screenshot of one of the slices. from what I see it is going a little far in the
            medial and lateral parts. I am using a 3TC image taken by Philips device. Is there any way to limit the
            region of interest before running the recon-all to only segment the thalamus and may give better
            results?
            Thank you

            Dorsa

            On Wed, Oct 19, 2016 at 5:21 PM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
                  Hi Dorsa

                  why do you think it  is going out too far? What intensity volume are you
                  overlaying it on? Many segmentations miss the lateral parts of the
                  thalamus since they have so much myelin in them

                  cheers
                  Bruce
                  On Wed, 19 Oct 2016, Dorsa
                  Haji Ghaffari wrote:

                  > Hi,
                  > I have done the sub-cortical segmentation in Freesurfer and have extracted the left
                  thalamus, when I put
                  > it on top of the original MRI, it seems like it is getting out of the border of thalamus,
                  also it is not
                  > smooth. I wanted to ask if anyone knows how to limit the computation only to thalamus, and
                  also make it
                  > trace the thalamus more accurately?
                  >
                  > Thank you
                  >
                  > Dorsa
                  >
                  >
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On Thu, Oct 20, 2016 at 9:51 AM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
      Hi Dorsa

      if you upload your subject I'll take a look. What is a 3TC image? I don't know what contrast the image you sent is
      but I would be cautious about only using it to assess the accuracy of the T1 segmentation

      cheers
      Bruce

      On Wed, 19 Oct 2016, Dorsa Haji Ghaffari wrote:

            I have attached a screenshot of one of the slices. from what I see it is going a little far in the
            medial and lateral parts. I am using a 3TC image taken by Philips device. Is there any way to limit the
            region of interest before running the recon-all to only segment the thalamus and may give better
            results?
            Thank you

            Dorsa

            On Wed, Oct 19, 2016 at 5:21 PM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
                  Hi Dorsa

                  why do you think it  is going out too far? What intensity volume are you
                  overlaying it on? Many segmentations miss the lateral parts of the
                  thalamus since they have so much myelin in them

                  cheers
                  Bruce
                  On Wed, 19 Oct 2016, Dorsa
                  Haji Ghaffari wrote:

                  > Hi,
                  > I have done the sub-cortical segmentation in Freesurfer and have extracted the left
                  thalamus, when I put
                  > it on top of the original MRI, it seems like it is getting out of the border of thalamus,
                  also it is not
                  > smooth. I wanted to ask if anyone knows how to limit the computation only to thalamus, and
                  also make it
                  > trace the thalamus more accurately?
                  >
                  > Thank you
                  >
                  > Dorsa
                  >
                  >
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            addressed. If you believe this e-mail was sent to you in error and the e-mail
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            but does not contain patient information, please contact the sender and properly
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