Dear group,<div><br></div>I am new to FS and the ADNI protocol, thus my question: is it ok to have a slice thickness of 1.2 mm <span></span>and in-plane resolution of 1.05 mm for cortical segmentation and brain volume analyses? This seems to be a sequence suggested on the FreeSurferWiki (I am using a GE750 3T). <div><br></div><div>Doesn&#39;t the anisotropic resolution introduce a bias?</div><div><br></div><div>Thanks a lot!</div><div><br></div><br><br><br>-- <br><div dir="ltr">Antonio Algaze, PhD<div>University of Puerto Rico</div><div>Physics, UPR-Bayamón</div><div>Radiology, UPR-School of Medicine</div></div><br>