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Hi Bruce,Sorry for the late reply. I have been searching the forum and the freesurfer wiki. Are there instructions somewhere on how to do this in matlab?Thanks,LindsayOn Thu, Dec 20, 2018 at 2:41 PM lindsay hanford <lindsay.hanford@gmail.com> wrote:Hello Freesurfer Community,I am wondering if it is possible to recalculate cortical thickness metrics (perhaps using mri_segstats or aparcstats2table) while including either a SD threshold or an exclusion mask.Using mri_surf2surf to register scans to the same space and then mri_surface_stats to create the std maps I have been comparing the variability of cortical thickness across the cortex for multiple scans across the same subject. From this I can determine a SD threshold point (0.5 say) or create a mask that includes all regions above that threshold.I would like to use this to threshold the regions showing the highest variability out of my calculations for mean hemispheric thickness and also regional thickness.Is there a way to use an SD threshold within mri_segstats or aparcstats2table? Otherwise apply a mask image to exclude specific vertices?Thank you in advance,Lindsay--Lindsay Hanford, PhDThe Buckner Laboratory | Harvard University280 Northwest Laboratory, 52 Oxford St | Cambridge, MA 02138412-218-4368 | lindsay.hanford@gmail.com