$Id: mri_coreg.c,v 1.27 2016/04/30 15:11:49 greve Exp $ cwd /lustre1/u/krystaly/4th cmdline mri_coreg --mov /lustre1/u/krystaly/4th/FLAIR/171_FLAIR.nii --ref 171.nii --reg 171_flairToT1.lta sysname Linux hostname GPA-4-10 machine x86_64 user krystaly dof 6 nsep 2 cras0 1 ftol 0.000000 linmintol 0.001000 bf 1 bflim 30.000000 bfnsamp 30 SmoothRef 0 SatPct 99.990000 MovOOB 0 optschema 1 Seed 53 Reading in mov /lustre1/u/krystaly/4th/FLAIR/171_FLAIR.nii Reading in ref 171.nii Setting cras translation parameters to align volume centers Creating random numbers for coordinate dithering Performing intensity dithering Performing intensity dithering on mov with computed dither Init matrix params 1.6038 4.1181 9.9581 0.0000 0.0000 0.0000 1.0000 1.0000 1.0000 0.0000 0.0000 0.0000 Initial parameters to be opt 1.6038 4.1181 9.9581 0.0000 0.0000 0.0000 Separation list (2): 4 2 min = 2 DoSmoothing 1 DoCoordDither 1 DoIntensityDither 1 nitersmax 4 ftol 1.000e-07 linmintol 1.000e-03 SatPct 99.990000 Hist FWHM 7.000000 7.000000 nthreads 8 movsat = 3988.0000 mov gstd 0.9317 0.9495 0.9495 Smoothing mov refsat = 8597.0000 ref gstd 0.9457 0.9457 0.9457 Smoothing ref COREGpreproc() done Testing if mov and target overlap Init cost -1.0632428695 nhits = 1143759 out of 87031808, Percent Overlap: 84.1 Initial RefRAS-to-MovRAS 1.00000 0.00000 0.00000 1.60375; 0.00000 1.00000 0.00000 4.11809; 0.00000 0.00000 1.00000 9.95814; 0.00000 0.00000 0.00000 1.00000; Initial RefVox-to-MovVox 0.83311 -0.01282 0.01403 -4.68936; 0.01444 1.06058 0.11182 -46.43644; -0.01958 -0.11155 1.06052 16.27637; 0.00000 0.00000 0.00000 1.00000; sep = 4 ----------------------------------- COREGoptBruteForce() 30 1 30 Turning on MovOOB for BruteForce Search #BF# sep= 4 iter=0 lim=30.0 delta=2.00 -0.39625 2.11809 1.95814 -2.00000 0.00000 0.00000 -1.0769826 Turning MovOOB back off after brute force search --------------------------------- Init Powel Params dof = 6: -0.396248 2.118088 1.958138 -2.000000 0.000000 0.000000 Starting OpenPowel2(), sep = 4 InitialCost -1.0871193409 #@# 4 188 -0.39625 2.11809 1.95814 -2.00000 0.00000 0.00000 -1.0871193 fs_powell::minimize nparams 6 maxfev 4 ftol 0.000000 linmin_xtol_ 0.001000 powell nthiter 0: fret = -1.087119 #@# 4 194 -0.01428 2.11809 1.95814 -2.00000 0.00000 0.00000 -1.0871735 #@# 4 195 -0.17008 2.11809 1.95814 -2.00000 0.00000 0.00000 -1.0872264 #@# 4 196 -0.17198 2.11809 1.95814 -2.00000 0.00000 0.00000 -1.0872265 #@# 4 198 -0.17844 2.11809 1.95814 -2.00000 0.00000 0.00000 -1.0872271 #@# 4 204 -0.17844 0.50005 1.95814 -2.00000 0.00000 0.00000 -1.0903175 #@# 4 208 -0.17844 0.73612 1.95814 -2.00000 0.00000 0.00000 -1.0904291 #@# 4 214 -0.17844 0.73745 0.34010 -2.00000 0.00000 0.00000 -1.0921063 #@# 4 215 -0.17844 0.73745 0.59888 -2.00000 0.00000 0.00000 -1.0924284 #@# 4 218 -0.17844 0.73745 0.79720 -2.00000 0.00000 0.00000 -1.0924916 #@# 4 219 -0.17844 0.73745 0.78437 -2.00000 0.00000 0.00000 -1.0924945 #@# 4 232 -0.17844 0.73745 0.78437 -1.61803 0.00000 0.00000 -1.0926158 #@# 4 233 -0.17844 0.73745 0.78437 -1.71515 0.00000 0.00000 -1.0926329 #@# 4 234 -0.17844 0.73745 0.78437 -1.71728 0.00000 0.00000 -1.0926330 #@# 4 235 -0.17844 0.73745 0.78437 -1.73948 0.00000 0.00000 -1.0926374 #@# 4 240 -0.17844 0.73745 0.78437 -1.74167 0.00000 0.00000 -1.0926379 #@# 4 259 -0.17844 0.73745 0.78437 -1.74267 0.00000 -0.61803 -1.0928656 #@# 4 261 -0.17844 0.73745 0.78437 -1.74267 0.00000 -0.45366 -1.0929039 #@# 4 262 -0.17844 0.73745 0.78437 -1.74267 0.00000 -0.44801 -1.0929040 #@# 4 263 -0.17844 0.73745 0.78437 -1.74267 0.00000 -0.44237 -1.0929041 powell nthiter 1: fret = -1.092904 #@# 4 279 -0.16349 0.73745 0.78437 -1.74267 0.00000 -0.43928 -1.0929055 #@# 4 280 -0.15713 0.73745 0.78437 -1.74267 0.00000 -0.43928 -1.0929056 #@# 4 291 -0.16183 0.72096 0.78437 -1.74267 0.00000 -0.43928 -1.0929062 #@# 4 304 -0.16183 0.72451 0.73678 -1.74267 0.00000 -0.43928 -1.0929145 #@# 4 305 -0.16183 0.72451 0.71346 -1.74267 0.00000 -0.43928 -1.0929219 #@# 4 311 -0.16183 0.72451 0.71576 -1.74267 0.00000 -0.43928 -1.0929222 #@# 4 348 -0.16183 0.72451 0.71576 -1.74267 0.00000 -0.44117 -1.0929223 #@# 4 350 -0.16183 0.72451 0.71576 -1.74267 0.00000 -0.44317 -1.0929224 powell nthiter 2: fret = -1.092922 Powell done niters total = 2 OptTimeSec 21.6 sec OptTimeMin 0.36 min nEvals 422 Final optimized parameters -0.16182809 0.72451311 0.71576178 -1.74266744 0.00000000 -0.44316879 Final matrix parameters -0.1618 0.7245 0.7158 -1.7427 0.0000 -0.4442 1.0000 1.0000 1.0000 0.0000 0.0000 0.0000 Final cost -1.092922396639491 --------------------------------- sep = 2 ----------------------------------- --------------------------------- Init Powel Params dof = 6: -0.161828 0.724513 0.715762 -1.742667 0.000000 -0.443169 Starting OpenPowel2(), sep = 2 InitialCost -1.0929187536 #@# 2 424 -0.16183 0.72451 0.71576 -1.74267 0.00000 -0.44317 -1.0929188 fs_powell::minimize nparams 6 maxfev 4 ftol 0.000000 linmin_xtol_ 0.001000 powell nthiter 0: fret = -1.092919 #@# 2 432 -0.15842 0.72451 0.71576 -1.74267 0.00000 -0.44317 -1.0929189 #@# 2 462 -0.16042 0.72251 0.72020 -1.74267 0.00000 -0.44317 -1.0929191 #@# 2 472 -0.16042 0.72251 0.72191 -1.71919 0.00000 -0.44317 -1.0929192 #@# 2 480 -0.16042 0.72251 0.72191 -1.72222 0.00000 -0.44317 -1.0929193 #@# 2 488 -0.16042 0.72251 0.72191 -1.72106 0.01235 -0.44317 -1.0929202 #@# 2 490 -0.16042 0.72251 0.72191 -1.72106 0.01677 -0.44317 -1.0929203 powell nthiter 1: fret = -1.092920 #@# 2 517 -0.16454 0.72251 0.72191 -1.72106 0.01677 -0.43863 -1.0929204 powell nthiter 2: fret = -1.092920 Powell done niters total = 2 OptTimeSec 154.5 sec OptTimeMin 2.58 min nEvals 664 Final optimized parameters -0.16348550 0.72115117 0.72191423 -1.72106194 0.01677352 -0.44474339 Final matrix parameters -0.1635 0.7212 0.7219 -1.7211 0.0168 -0.4447 1.0000 1.0000 1.0000 0.0000 0.0000 0.0000 Final cost -1.092920407357750 --------------------------------- Final RefRAS-to-MovRAS 0.99997 -0.00776 0.00029 -0.16349; 0.00777 0.99952 -0.03003 0.72115; -0.00006 0.03004 0.99955 0.72191; 0.00000 0.00000 0.00000 1.00000; Final RefVox-to-MovVox 0.83299 -0.01977 0.01348 -5.33723; 0.02394 1.06326 0.08024 -47.19425; -0.01911 -0.07981 1.06339 -12.72433; 0.00000 0.00000 0.00000 1.00000; Final matrix parameters -0.1635 0.7212 0.7219 -1.7211 0.0168 -0.4447 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 Final opt parameters -0.1635 0.7212 0.7219 -1.7211 0.0168 -0.4447 nhits = 9070855 out of 87031808, Percent Overlap: 83.4 mri_coreg RunTimeSec 456.7 sec To check run: tkregisterfv --mov /lustre1/u/krystaly/4th/FLAIR/171_FLAIR.nii --targ 171.nii --reg 171_flairToT1.lta mri_coreg done regio_read_register: loading lta Matrix from regfile: 0.99959 -0.01618 -0.02373 1.60248; 0.01792 0.99704 0.07483 -9.42331; 0.02244 -0.07523 0.99691 3.04041; 0.00000 0.00000 0.00000 1.00000; movvol /lustre1/u/krystaly/4th/FLAIR/171_FLAIR.nii targvol 171.nii outvol 171_flair_reg.nii regfile 171_flairToT1.lta invert 0 tal 0 talres 2 regheader 0 noresample 0 interp trilinear (1) precision float (3) Gdiag_no -1 Synth 0 SynthSeed 1711786524 Final tkRAS-to-tkRAS Matrix is: 0.99959 -0.01618 -0.02373 1.60248; 0.01792 0.99704 0.07483 -9.42331; 0.02244 -0.07523 0.99691 3.04041; 0.00000 0.00000 0.00000 1.00000; Vox2Vox Matrix is: 0.83299 -0.01977 0.01348 -5.33723; 0.02394 1.06326 0.08024 -47.19424; -0.01911 -0.07981 1.06339 -12.72435; 0.00000 0.00000 0.00000 1.00000; Resampling Output registration matrix is identity mri_vol2vol done Constructing image-to-world transform from header information (/lustre1/u/krystaly/4th/171.nii) Read image: /lustre1/u/krystaly/4th/171.nii Constructing image-to-world transform from header information (/share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/template.nii) Read image: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/template.nii Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE min: 0 max: 9881 robustMin: 0 robustMax: 7788.18 histogram[ 0 ]: 19647 histogram[ 1 ]: 6939 histogram[ 2 ]: 7868 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.0474364 cumulativeHistogram[ 1 ]: 0.0641901 cumulativeHistogram[ 2 ]: 0.0831869 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 AFFINE min: 0 max: 9881 robustMin: 0 robustMax: 7788.18 histogram[ 0 ]: 19647 histogram[ 1 ]: 6939 histogram[ 2 ]: 7868 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.0474364 cumulativeHistogram[ 1 ]: 0.0641901 cumulativeHistogram[ 2 ]: 0.0831869 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 0 min: 0 max: 9881 robustMin: 0 robustMax: 7788.18 histogram[ 0 ]: 19647 histogram[ 1 ]: 6939 histogram[ 2 ]: 7868 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.0474364 cumulativeHistogram[ 1 ]: 0.0641901 cumulativeHistogram[ 2 ]: 0.0831869 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 0 min: 0 max: 9881 robustMin: 0 robustMax: 7788.18 histogram[ 0 ]: 19647 histogram[ 1 ]: 6939 histogram[ 2 ]: 7868 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.0474364 cumulativeHistogram[ 1 ]: 0.0641901 cumulativeHistogram[ 2 ]: 0.0831869 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 0 min: 0 max: 9881 robustMin: 0 robustMax: 7788.18 histogram[ 0 ]: 19647 histogram[ 1 ]: 6939 histogram[ 2 ]: 7868 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.0474364 cumulativeHistogram[ 1 ]: 0.0641901 cumulativeHistogram[ 2 ]: 0.0831869 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Constructing image-to-world transform from header information (/lustre1/u/krystaly/4th/171.nii) Read image: /lustre1/u/krystaly/4th/171.nii Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level1.txt.gz Transforming points Transforming points 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level1.txt.gz Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 1 [BRACKETING] Found a really good solution -- no need for zooming: 1 ----------------------- [BRACKETING] Hit a really bad solution -- ready for zooming: 6.92123 [ZOOMING] Zooming with low=0 and high=6.92123 bisected: 3.46061 [ZOOMING] Found a good solution: 3.46061 ----------------------- [BRACKETING] Hit a really bad solution -- ready for zooming: 4.68361 [ZOOMING] Zooming with low=0 and high=4.68361 bisected: 2.3418 [ZOOMING] Found a good solution: 2.3418 ----------------------- [BRACKETING] Hit a really bad solution -- ready for zooming: 21.5234 [ZOOMING] Zooming with low=0 and high=21.5234 bisected: 10.7617 bisected: 5.38084 bisected: 2.69042 [ZOOMING] Found a good solution: 2.69042 ----------------------- [BRACKETING] Hit a really bad solution -- ready for zooming: 4.65532 [ZOOMING] Zooming with low=0 and high=4.65532 bisected: 2.32766 bisected: 1.16383 [ZOOMING] Found a good solution: 1.16383 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 1.23762 ----------------------- [BRACKETING] Hit a really bad solution -- ready for zooming: 6.38549 [ZOOMING] Zooming with low=0 and high=6.38549 bisected: 3.19274 bisected: 1.59637 [ZOOMING] Found a good solution: 1.59637 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.811001 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.134634 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.046615 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0529974 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0413238 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0243822 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0112434 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0650517 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0553076 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0661075 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0128798 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.00715372 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.00244513 ----------------------- Optimizer: maximalDeformation is too small; stopping 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 0.159155 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz Read mesh collection: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz Constructing image-to-world transform from header information (/lustre1/u/krystaly/4th/171.nii) Read image: /lustre1/u/krystaly/4th/171.nii ##---------------------------------------------- Samsegment Options ##---------------------------------------------- output directory: /lustre1/u/krystaly/4th/171_SamsegOutput/ input images: /lustre1/u/krystaly/4th/171.nii, /lustre1/u/krystaly/4th/171_flair_reg.nii modelSpecifications: {'FreeSurferLabels': [0, 165, 258, 16, 24, 8, 47, 15, 259, 3, 42, 7, 46, 41, 2, 63, 54, 18, 53, 44, 17, 31, 5, 85, 60, 28, 14, 26, 12, 51, 62, 58, 4, 30, 43, 52, 11, 49, 13, 50, 10, 72, 29, 99], 'atlasFileName': '/share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz', 'names': ['Unknown', 'Skull', 'Soft_Nonbrain_Tissue', 'Brain-Stem', 'CSF', 'Left-Cerebellum-Cortex', 'Right-Cerebellum-Cortex', '4th-Ventricle', 'Fluid_Inside_Eyes', 'Left-Cerebral-Cortex', 'Right-Cerebral-Cortex', 'Left-Cerebellum-White-Matter', 'Right-Cerebellum-White-Matter', 'Right-Cerebral-White-Matter', 'Left-Cerebral-White-Matter', 'Right-choroid-plexus', 'Right-Amygdala', 'Left-Amygdala', 'Right-Hippocampus', 'Right-Inf-Lat-Vent', 'Left-Hippocampus', 'Left-choroid-plexus', 'Left-Inf-Lat-Vent', 'Optic-Chiasm', 'Right-VentralDC', 'Left-VentralDC', '3rd-Ventricle', 'Left-Accumbens-area', 'Left-Putamen', 'Right-Putamen', 'Right-vessel', 'Right-Accumbens-area', 'Left-Lateral-Ventricle', 'Left-vessel', 'Right-Lateral-Ventricle', 'Right-Pallidum', 'Left-Caudate', 'Right-Thalamus', 'Left-Pallidum', 'Right-Caudate', 'Left-Thalamus', '5th-Ventricle', 'Left-undetermined', 'Lesions'], 'colors': [[0, 0, 0, 0], [255, 165, 0, 255], [128, 128, 128, 255], [119, 159, 176, 255], [60, 60, 60, 255], [230, 148, 34, 255], [230, 148, 34, 255], [42, 204, 164, 255], [128, 0, 128, 255], [205, 62, 78, 255], [205, 62, 78, 255], [220, 248, 164, 255], [220, 248, 164, 255], [0, 225, 0, 255], [245, 245, 245, 255], [0, 200, 221, 255], [103, 255, 255, 255], [103, 255, 255, 255], [220, 216, 20, 255], [196, 58, 250, 255], [220, 216, 20, 255], [0, 200, 200, 255], [196, 58, 250, 255], [234, 169, 30, 255], [165, 42, 42, 255], [165, 42, 42, 255], [204, 182, 142, 255], [255, 165, 0, 255], [236, 13, 176, 255], [236, 13, 176, 255], [160, 32, 240, 255], [255, 165, 0, 255], [120, 18, 134, 255], [160, 32, 240, 255], [120, 18, 134, 255], [13, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [12, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [120, 190, 150, 255], [135, 206, 235, 255], [255, 0, 0, 255]], 'sharedGMMParameters': [GMMparameter(mergedName='Unknown', numberOfComponents=1, searchStrings=['Unknown', 'Skull', 'undetermined']), GMMparameter(mergedName='GlobalWM', numberOfComponents=1, searchStrings=['White', 'Brain-Stem', 'VentralDC', 'Optic-Chiasm', 'Thalamus']), GMMparameter(mergedName='GlobalGM', numberOfComponents=1, searchStrings=['Cortex', 'Caudate', 'Hippocampus', 'Amygdala', 'Accumbens', 'Thalamus']), GMMparameter(mergedName='GlobalCSF_messy', numberOfComponents=1, searchStrings=['CSF', 'vessel', 'choroid-plexus', 'Fluid']), GMMparameter(mergedName='GlobalCSF_clean', numberOfComponents=1, searchStrings=['Ventricle', 'Inf-Lat-Vent', 'Fluid']), GMMparameter(mergedName='Putamen', numberOfComponents=1, searchStrings=['Putamen']), GMMparameter(mergedName='Pallidum', numberOfComponents=1, searchStrings=['Pallidum']), GMMparameter(mergedName='Lesions', numberOfComponents=1, searchStrings=['Lesions']), GMMparameter(mergedName='Soft', numberOfComponents=3, searchStrings=['Soft'])], 'useDiagonalCovarianceMatrices': True, 'maskingProbabilityThreshold': 0.5, 'maskingDistance': 10.0, 'K': 0.1, 'biasFieldSmoothingKernelSize': 50, 'whiteMatterAndCortexSmoothingSigma': 0} optimizationOptions: {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '/share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level1.txt.gz', 'targetDownsampledVoxelSpacing': 2.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}, {'atlasFileName': '/share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} Unknown Unknown (100%) Skull (100%) Left-undetermined (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Thalamus (50%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Pallidum Right-Pallidum (100%) Left-Pallidum (100%) Lesions Lesions (100%) Soft Soft_Nonbrain_Tissue (100%) Unknown Unknown (100%) Skull (100%) Left-undetermined (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Thalamus (50%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Pallidum Right-Pallidum (100%) Left-Pallidum (100%) Lesions Lesions (100%) Soft Soft_Nonbrain_Tissue (100%) performing affine atlas registration image: /lustre1/u/krystaly/4th/171.nii template: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/template.nii maximalDeformation=1.0000 minLogLikelihood=-0.8051 maximalDeformation=3.3303 minLogLikelihood=-0.8617 maximalDeformation=2.0421 minLogLikelihood=-0.8768 maximalDeformation=0.6025 minLogLikelihood=-0.8789 maximalDeformation=2.0221 minLogLikelihood=-0.8879 maximalDeformation=2.1544 minLogLikelihood=-0.8974 maximalDeformation=3.0588 minLogLikelihood=-0.8979 maximalDeformation=0.5012 minLogLikelihood=-0.8987 maximalDeformation=0.2037 minLogLikelihood=-0.8988 maximalDeformation=0.2880 minLogLikelihood=-0.8989 maximalDeformation=0.0877 minLogLikelihood=-0.8989 maximalDeformation=0.0000 minLogLikelihood=-0.8989 appliedScaling: 0.9928 maximalDeformation=1.0000 minLogLikelihood=-0.9073 maximalDeformation=0.1933 minLogLikelihood=-0.9089 maximalDeformation=0.0985 minLogLikelihood=-0.9092 maximalDeformation=0.1797 minLogLikelihood=-0.9098 maximalDeformation=0.0000 minLogLikelihood=-0.9098 appliedScaling: 0.9949 maximalDeformation=0.2348 minLogLikelihood=-0.9115 maximalDeformation=0.1632 minLogLikelihood=-0.9118 maximalDeformation=0.0399 minLogLikelihood=-0.9118 maximalDeformation=0.0369 minLogLikelihood=-0.9120 maximalDeformation=0.1980 minLogLikelihood=-0.9129 maximalDeformation=0.0000 minLogLikelihood=-0.9129 appliedScaling: 0.9982 writing template transform to /lustre1/u/krystaly/4th/171_SamsegOutput/template.lta writing talairach transform to /lustre1/u/krystaly/4th/171_SamsegOutput/samseg.talairach.lta atlas registration complete: 0:01:03.952988 [0.49999899 0.5 0.5 ] Unknown Unknown (100%) Skull (100%) Left-undetermined (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Thalamus (50%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Pallidum Right-Pallidum (100%) Left-Pallidum (100%) Lesions Lesions (100%) Soft Soft_Nonbrain_Tissue (100%) ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level1.txt.gz targetDownsampledVoxelSpacing: 2.0 maximumNumberOfIterations: 100 estimateBiasField: True }, { depth: 2 atlasFileName: /share1/FreeSurfer/7.3.2/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2_lesion/atlas_level2.txt.gz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=1.0000 minLogLikelihood=751131.8606 Total time spent: 0.3113 sec maximalDeformation=0.8079 minLogLikelihood=745691.3244 Total time spent: 0.1292 sec maximalDeformation=0.6171 minLogLikelihood=741885.1481 Total time spent: 0.1397 sec maximalDeformation=0.8088 minLogLikelihood=736958.0381 Total time spent: 0.1234 sec maximalDeformation=0.3502 minLogLikelihood=734970.1246 Total time spent: 0.1331 sec maximalDeformation=0.2516 minLogLikelihood=733641.3532 Total time spent: 0.1532 sec maximalDeformation=0.4771 minLogLikelihood=731225.5767 Total time spent: 0.1992 sec maximalDeformation=0.2460 minLogLikelihood=730267.8319 Total time spent: 0.1404 sec maximalDeformation=0.3155 minLogLikelihood=728787.1451 Total time spent: 0.1243 sec maximalDeformation=0.3411 minLogLikelihood=727977.7157 Total time spent: 0.1399 sec maximalDeformation=0.4200 minLogLikelihood=726644.1346 Total time spent: 0.1024 sec maximalDeformation=0.5395 minLogLikelihood=726105.3743 Total time spent: 0.1342 sec maximalDeformation=0.1377 minLogLikelihood=725920.9596 Total time spent: 0.2126 sec maximalDeformation=0.2387 minLogLikelihood=725525.3135 Total time spent: 0.1043 sec maximalDeformation=0.1510 minLogLikelihood=725336.1142 Total time spent: 0.1237 sec maximalDeformation=0.1251 minLogLikelihood=725077.6033 Total time spent: 0.1033 sec maximalDeformation=0.1856 minLogLikelihood=724860.5072 Total time spent: 0.1246 sec maximalDeformation=0.0952 minLogLikelihood=724833.3427 Total time spent: 0.1656 sec maximalDeformation=0.1374 minLogLikelihood=724703.7503 Total time spent: 0.1065 sec maximalDeformation=0.1241 minLogLikelihood=724615.4687 Total time spent: 0.1037 sec maximalDeformation=0.0000 minLogLikelihood=724615.4687 Total time spent: 0.0000 sec maximalDeformationApplied: 2.8881 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.5000 minLogLikelihood=639253.9414 Total time spent: 0.3519 sec maximalDeformation=0.3151 minLogLikelihood=638529.7596 Total time spent: 0.1006 sec maximalDeformation=0.3711 minLogLikelihood=638184.5467 Total time spent: 0.0991 sec maximalDeformation=0.1811 minLogLikelihood=638040.6133 Total time spent: 0.1219 sec maximalDeformation=0.2365 minLogLikelihood=637842.1250 Total time spent: 0.1104 sec maximalDeformation=0.1622 minLogLikelihood=637686.2930 Total time spent: 0.1626 sec maximalDeformation=0.0933 minLogLikelihood=637523.8591 Total time spent: 0.1533 sec maximalDeformation=0.2612 minLogLikelihood=637314.2381 Total time spent: 0.1073 sec maximalDeformation=0.1760 minLogLikelihood=637122.3036 Total time spent: 0.0958 sec maximalDeformation=0.3997 minLogLikelihood=636784.1580 Total time spent: 0.0995 sec maximalDeformation=0.1747 minLogLikelihood=636605.1748 Total time spent: 0.1354 sec maximalDeformation=0.2391 minLogLikelihood=636363.6571 Total time spent: 0.3045 sec maximalDeformation=0.1836 minLogLikelihood=636014.9366 Total time spent: 0.1249 sec maximalDeformation=0.1294 minLogLikelihood=635853.8823 Total time spent: 0.2492 sec maximalDeformation=0.0381 minLogLikelihood=635790.9858 Total time spent: 0.2392 sec maximalDeformation=0.1917 minLogLikelihood=635623.5369 Total time spent: 0.1238 sec maximalDeformation=0.2460 minLogLikelihood=635543.6124 Total time spent: 0.1059 sec maximalDeformation=0.0582 minLogLikelihood=635488.8703 Total time spent: 0.1042 sec maximalDeformation=0.1581 minLogLikelihood=635257.6438 Total time spent: 0.1783 sec maximalDeformation=0.2422 minLogLikelihood=634990.6493 Total time spent: 0.1654 sec maximalDeformation=0.0000 minLogLikelihood=634990.6493 Total time spent: 0.0000 sec maximalDeformationApplied: 1.6984 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=0.5000 minLogLikelihood=634585.3292 Total time spent: 0.3271 sec maximalDeformation=0.1607 minLogLikelihood=634453.9977 Total time spent: 0.0920 sec maximalDeformation=0.1819 minLogLikelihood=634303.3033 Total time spent: 0.1239 sec maximalDeformation=0.1034 minLogLikelihood=634208.5104 Total time spent: 0.2018 sec maximalDeformation=0.1984 minLogLikelihood=634085.7794 Total time spent: 0.1365 sec maximalDeformation=0.2328 minLogLikelihood=633985.9198 Total time spent: 0.0907 sec maximalDeformation=0.1233 minLogLikelihood=633882.2514 Total time spent: 0.1009 sec maximalDeformation=0.1013 minLogLikelihood=633762.5817 Total time spent: 0.1192 sec maximalDeformation=0.2161 minLogLikelihood=633631.4712 Total time spent: 0.1306 sec maximalDeformation=0.1393 minLogLikelihood=633568.6637 Total time spent: 0.1369 sec maximalDeformation=0.1758 minLogLikelihood=633490.1243 Total time spent: 0.0997 sec maximalDeformation=0.1379 minLogLikelihood=633410.0258 Total time spent: 0.1001 sec maximalDeformation=0.0937 minLogLikelihood=633348.5385 Total time spent: 0.1920 sec maximalDeformation=0.1465 minLogLikelihood=633250.9955 Total time spent: 0.1519 sec maximalDeformation=0.1504 minLogLikelihood=633130.2086 Total time spent: 0.1259 sec maximalDeformation=0.0891 minLogLikelihood=633059.3599 Total time spent: 0.2248 sec maximalDeformation=0.1042 minLogLikelihood=633007.2211 Total time spent: 0.1040 sec maximalDeformation=0.2306 minLogLikelihood=632940.0735 Total time spent: 0.1040 sec maximalDeformation=0.1808 minLogLikelihood=632783.6939 Total time spent: 0.1033 sec maximalDeformation=0.3551 minLogLikelihood=632569.0123 Total time spent: 0.2778 sec maximalDeformation=0.0000 minLogLikelihood=632569.0123 Total time spent: 0.0000 sec maximalDeformationApplied: 1.3182 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=0.5000 minLogLikelihood=632492.8429 Total time spent: 0.3370 sec maximalDeformation=0.0771 minLogLikelihood=632455.6788 Total time spent: 0.1042 sec maximalDeformation=0.1838 minLogLikelihood=632353.2623 Total time spent: 0.1001 sec maximalDeformation=0.2525 minLogLikelihood=632330.2161 Total time spent: 0.1138 sec maximalDeformation=0.0443 minLogLikelihood=632310.3497 Total time spent: 0.0993 sec maximalDeformation=0.1345 minLogLikelihood=632267.6750 Total time spent: 0.0966 sec maximalDeformation=0.0400 minLogLikelihood=632254.3841 Total time spent: 0.2482 sec maximalDeformation=0.1507 minLogLikelihood=632192.6538 Total time spent: 0.0969 sec maximalDeformation=0.1766 minLogLikelihood=632152.5424 Total time spent: 0.0982 sec maximalDeformation=0.1095 minLogLikelihood=632094.7959 Total time spent: 0.0972 sec maximalDeformation=0.1983 minLogLikelihood=632018.4534 Total time spent: 0.0985 sec maximalDeformation=0.1158 minLogLikelihood=632015.4472 Total time spent: 0.1418 sec maximalDeformation=0.0953 minLogLikelihood=631998.8616 Total time spent: 0.1024 sec maximalDeformation=0.1220 minLogLikelihood=631942.7447 Total time spent: 0.1047 sec maximalDeformation=0.0879 minLogLikelihood=631895.2542 Total time spent: 0.1289 sec maximalDeformation=0.1226 minLogLikelihood=631843.6566 Total time spent: 0.1424 sec maximalDeformation=0.1499 minLogLikelihood=631811.1162 Total time spent: 0.1269 sec maximalDeformation=0.0703 minLogLikelihood=631781.0776 Total time spent: 0.1066 sec maximalDeformation=0.2510 minLogLikelihood=631718.7582 Total time spent: 0.1041 sec maximalDeformation=0.2158 minLogLikelihood=631644.0735 Total time spent: 0.1076 sec maximalDeformation=0.0000 minLogLikelihood=631644.0735 Total time spent: 0.0000 sec maximalDeformationApplied: 1.2300 ======================================================= iterationNumber: 4 EM converged! maximalDeformation=0.2500 minLogLikelihood=631554.3256 Total time spent: 0.3421 sec maximalDeformation=0.1402 minLogLikelihood=631510.6283 Total time spent: 0.0988 sec maximalDeformation=0.0676 minLogLikelihood=631480.8402 Total time spent: 0.1023 sec maximalDeformation=0.0940 minLogLikelihood=631451.9764 Total time spent: 0.1086 sec maximalDeformation=0.1069 minLogLikelihood=631427.5983 Total time spent: 0.1035 sec maximalDeformation=0.0912 minLogLikelihood=631404.5099 Total time spent: 0.0977 sec maximalDeformation=0.1067 minLogLikelihood=631387.3907 Total time spent: 0.0949 sec maximalDeformation=0.0745 minLogLikelihood=631370.9779 Total time spent: 0.0910 sec maximalDeformation=0.0927 minLogLikelihood=631352.7560 Total time spent: 0.0901 sec maximalDeformation=0.0956 minLogLikelihood=631333.9125 Total time spent: 0.0907 sec maximalDeformation=0.0751 minLogLikelihood=631314.3750 Total time spent: 0.0924 sec maximalDeformation=0.0716 minLogLikelihood=631292.8413 Total time spent: 0.0970 sec maximalDeformation=0.0883 minLogLikelihood=631269.8972 Total time spent: 0.1052 sec maximalDeformation=0.0911 minLogLikelihood=631247.5280 Total time spent: 0.0989 sec maximalDeformation=0.0905 minLogLikelihood=631222.4449 Total time spent: 0.0988 sec maximalDeformation=0.1084 minLogLikelihood=631194.4970 Total time spent: 0.1060 sec maximalDeformation=0.1003 minLogLikelihood=631168.5297 Total time spent: 0.0967 sec maximalDeformation=0.0809 minLogLikelihood=631143.9705 Total time spent: 0.0996 sec maximalDeformation=0.0752 minLogLikelihood=631120.3219 Total time spent: 0.1078 sec maximalDeformation=0.0792 minLogLikelihood=631097.9256 Total time spent: 0.1016 sec maximalDeformation=0.0000 minLogLikelihood=631097.9256 Total time spent: 0.0000 sec maximalDeformationApplied: 0.9452 ======================================================= iterationNumber: 5 EM converged! maximalDeformation=0.0656 minLogLikelihood=631053.0749 Total time spent: 0.4502 sec maximalDeformation=0.0840 minLogLikelihood=631040.2862 Total time spent: 0.1050 sec maximalDeformation=0.0612 minLogLikelihood=631031.7794 Total time spent: 0.1034 sec maximalDeformation=0.0362 minLogLikelihood=631024.3291 Total time spent: 0.1002 sec maximalDeformation=0.0508 minLogLikelihood=631017.7831 Total time spent: 0.1024 sec maximalDeformation=0.0422 minLogLikelihood=631010.3489 Total time spent: 0.1031 sec maximalDeformation=0.0633 minLogLikelihood=631003.8166 Total time spent: 0.0984 sec maximalDeformation=0.0426 minLogLikelihood=630998.4539 Total time spent: 0.1022 sec maximalDeformation=0.0351 minLogLikelihood=630992.9329 Total time spent: 0.0984 sec maximalDeformation=0.0385 minLogLikelihood=630988.6322 Total time spent: 0.0980 sec maximalDeformation=0.0558 minLogLikelihood=630984.0063 Total time spent: 0.0993 sec maximalDeformation=0.0617 minLogLikelihood=630978.4513 Total time spent: 0.1000 sec maximalDeformation=0.0512 minLogLikelihood=630973.5071 Total time spent: 0.1021 sec maximalDeformation=0.0408 minLogLikelihood=630968.9187 Total time spent: 0.1051 sec maximalDeformation=0.0349 minLogLikelihood=630964.0962 Total time spent: 0.0929 sec maximalDeformation=0.0378 minLogLikelihood=630959.3025 Total time spent: 0.0933 sec maximalDeformation=0.0440 minLogLikelihood=630953.9624 Total time spent: 0.0927 sec maximalDeformation=0.0853 minLogLikelihood=630949.7557 Total time spent: 0.0924 sec maximalDeformation=0.0269 minLogLikelihood=630943.9826 Total time spent: 0.0930 sec maximalDeformation=0.0609 minLogLikelihood=630937.3810 Total time spent: 0.0957 sec maximalDeformation=0.0000 minLogLikelihood=630937.3810 Total time spent: 0.0000 sec maximalDeformationApplied: 0.5001 ======================================================= iterationNumber: 6 EM converged! maximalDeformation=0.0559 minLogLikelihood=630911.3123 Total time spent: 0.4165 sec maximalDeformation=0.0243 minLogLikelihood=630907.2165 Total time spent: 0.0962 sec maximalDeformation=0.0522 minLogLikelihood=630904.3484 Total time spent: 0.0902 sec maximalDeformation=0.0284 minLogLikelihood=630901.2770 Total time spent: 0.0943 sec maximalDeformation=0.0580 minLogLikelihood=630898.5208 Total time spent: 0.0964 sec maximalDeformation=0.0370 minLogLikelihood=630896.0208 Total time spent: 0.0948 sec maximalDeformation=0.0734 minLogLikelihood=630892.7454 Total time spent: 0.0935 sec maximalDeformation=0.0481 minLogLikelihood=630890.9818 Total time spent: 0.0966 sec maximalDeformation=0.0336 minLogLikelihood=630888.7782 Total time spent: 0.0928 sec maximalDeformation=0.0408 minLogLikelihood=630886.6847 Total time spent: 0.0986 sec maximalDeformation=0.0274 minLogLikelihood=630884.8288 Total time spent: 0.1027 sec maximalDeformation=0.0399 minLogLikelihood=630882.4204 Total time spent: 0.0981 sec maximalDeformation=0.0246 minLogLikelihood=630880.1704 Total time spent: 0.0987 sec maximalDeformation=0.0203 minLogLikelihood=630877.7374 Total time spent: 0.1003 sec maximalDeformation=0.0235 minLogLikelihood=630875.3859 Total time spent: 0.1010 sec maximalDeformation=0.0241 minLogLikelihood=630872.7142 Total time spent: 0.1009 sec maximalDeformation=0.0378 minLogLikelihood=630869.9009 Total time spent: 0.1010 sec maximalDeformation=0.0337 minLogLikelihood=630866.9436 Total time spent: 0.0998 sec maximalDeformation=0.0274 minLogLikelihood=630863.8687 Total time spent: 0.0990 sec maximalDeformation=0.0311 minLogLikelihood=630860.7382 Total time spent: 0.0986 sec maximalDeformation=0.0000 minLogLikelihood=630860.7382 Total time spent: 0.0000 sec maximalDeformationApplied: 0.4951 ======================================================= iterationNumber: 7 EM converged! maximalDeformation=0.0573 minLogLikelihood=630839.1715 Total time spent: 0.4182 sec maximalDeformation=0.0189 minLogLikelihood=630836.8622 Total time spent: 0.0955 sec maximalDeformation=0.0318 minLogLikelihood=630835.3977 Total time spent: 0.0973 sec maximalDeformation=0.0140 minLogLikelihood=630834.0791 Total time spent: 0.1018 sec maximalDeformation=0.0238 minLogLikelihood=630832.3277 Total time spent: 0.1088 sec maximalDeformation=0.0252 minLogLikelihood=630831.2967 Total time spent: 0.1014 sec maximalDeformation=0.0156 minLogLikelihood=630829.9125 Total time spent: 0.0987 sec maximalDeformation=0.0216 minLogLikelihood=630828.3475 Total time spent: 0.0985 sec maximalDeformation=0.0188 minLogLikelihood=630827.0553 Total time spent: 0.0967 sec maximalDeformation=0.0305 minLogLikelihood=630825.5701 Total time spent: 0.0970 sec maximalDeformation=0.0226 minLogLikelihood=630824.0034 Total time spent: 0.1000 sec maximalDeformation=0.0227 minLogLikelihood=630822.2805 Total time spent: 0.1097 sec maximalDeformation=0.0294 minLogLikelihood=630820.6671 Total time spent: 0.0929 sec maximalDeformation=0.0218 minLogLikelihood=630819.0727 Total time spent: 0.1039 sec maximalDeformation=0.0212 minLogLikelihood=630817.4897 Total time spent: 0.1038 sec maximalDeformation=0.0206 minLogLikelihood=630816.1904 Total time spent: 0.1058 sec maximalDeformation=0.0130 minLogLikelihood=630814.6925 Total time spent: 0.1064 sec maximalDeformation=0.0184 minLogLikelihood=630813.0266 Total time spent: 0.1010 sec maximalDeformation=0.0254 minLogLikelihood=630811.4888 Total time spent: 0.1040 sec maximalDeformation=0.0253 minLogLikelihood=630809.5630 Total time spent: 0.1055 sec maximalDeformation=0.0000 minLogLikelihood=630809.5630 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2494 ======================================================= iterationNumber: 8 EM converged! maximalDeformation=0.0357 minLogLikelihood=630789.9566 Total time spent: 0.5060 sec maximalDeformation=0.0169 minLogLikelihood=630788.6866 Total time spent: 0.0895 sec maximalDeformation=0.0145 minLogLikelihood=630787.6496 Total time spent: 0.0957 sec maximalDeformation=0.0121 minLogLikelihood=630786.7397 Total time spent: 0.1007 sec maximalDeformation=0.0151 minLogLikelihood=630785.8499 Total time spent: 0.0996 sec maximalDeformation=0.0177 minLogLikelihood=630784.6727 Total time spent: 0.0985 sec maximalDeformation=0.0280 minLogLikelihood=630783.4649 Total time spent: 0.0933 sec maximalDeformation=0.0287 minLogLikelihood=630782.3384 Total time spent: 0.0972 sec maximalDeformation=0.0251 minLogLikelihood=630781.0244 Total time spent: 0.0969 sec maximalDeformation=0.0234 minLogLikelihood=630779.7055 Total time spent: 0.1014 sec maximalDeformation=0.0228 minLogLikelihood=630778.5550 Total time spent: 0.0955 sec maximalDeformation=0.0309 minLogLikelihood=630777.3592 Total time spent: 0.0985 sec maximalDeformation=0.0350 minLogLikelihood=630775.9862 Total time spent: 0.0981 sec maximalDeformation=0.0407 minLogLikelihood=630775.2229 Total time spent: 0.0968 sec maximalDeformation=0.0066 minLogLikelihood=630774.1133 Total time spent: 0.0990 sec maximalDeformation=0.0151 minLogLikelihood=630773.1960 Total time spent: 0.1004 sec maximalDeformation=0.0214 minLogLikelihood=630772.3156 Total time spent: 0.0985 sec maximalDeformation=0.0434 minLogLikelihood=630771.3431 Total time spent: 0.0979 sec maximalDeformation=0.0409 minLogLikelihood=630770.2110 Total time spent: 0.0989 sec maximalDeformation=0.0362 minLogLikelihood=630769.1404 Total time spent: 0.1045 sec maximalDeformation=0.0000 minLogLikelihood=630769.1404 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3560 ======================================================= iterationNumber: 0 EM converged! maximalDeformation=1.0000 minLogLikelihood=5081231.8192 Total time spent: 1.1351 sec maximalDeformation=0.4318 minLogLikelihood=5074256.9917 Total time spent: 0.7447 sec maximalDeformation=0.1583 minLogLikelihood=5071981.2118 Total time spent: 0.5301 sec maximalDeformation=1.3743 minLogLikelihood=5052144.6442 Total time spent: 0.3750 sec maximalDeformation=0.3504 minLogLikelihood=5048528.0886 Total time spent: 0.8021 sec maximalDeformation=0.2151 minLogLikelihood=5046911.2552 Total time spent: 0.5223 sec maximalDeformation=0.0611 minLogLikelihood=5046373.9572 Total time spent: 1.2815 sec maximalDeformation=0.0727 minLogLikelihood=5045564.0055 Total time spent: 0.3552 sec maximalDeformation=0.0873 minLogLikelihood=5044685.2440 Total time spent: 0.3765 sec maximalDeformation=0.1902 minLogLikelihood=5043472.8552 Total time spent: 0.8774 sec maximalDeformation=0.1701 minLogLikelihood=5041858.5182 Total time spent: 0.3657 sec maximalDeformation=0.3752 minLogLikelihood=5039692.9604 Total time spent: 0.6936 sec maximalDeformation=0.1555 minLogLikelihood=5037876.0873 Total time spent: 0.3852 sec maximalDeformation=0.0946 minLogLikelihood=5036480.2467 Total time spent: 0.3729 sec maximalDeformation=0.3602 minLogLikelihood=5031252.6354 Total time spent: 0.3612 sec maximalDeformation=0.5074 minLogLikelihood=5025792.0964 Total time spent: 0.4255 sec maximalDeformation=0.1375 minLogLikelihood=5024839.6062 Total time spent: 1.2379 sec maximalDeformation=0.1927 minLogLikelihood=5023491.0976 Total time spent: 0.3692 sec maximalDeformation=0.0472 minLogLikelihood=5023273.0199 Total time spent: 1.2220 sec maximalDeformation=0.5444 minLogLikelihood=5021534.0964 Total time spent: 0.3674 sec maximalDeformation=0.0000 minLogLikelihood=5021534.0964 Total time spent: 0.0000 sec maximalDeformationApplied: 3.2714 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.5000 minLogLikelihood=5009634.2721 Total time spent: 1.5022 sec maximalDeformation=0.5623 minLogLikelihood=5002562.0798 Total time spent: 0.7292 sec maximalDeformation=0.4403 minLogLikelihood=4999091.1646 Total time spent: 0.4739 sec maximalDeformation=0.3412 minLogLikelihood=4996625.3637 Total time spent: 0.6108 sec maximalDeformation=0.4151 minLogLikelihood=4994267.4173 Total time spent: 0.4738 sec maximalDeformation=0.2304 minLogLikelihood=4993547.9708 Total time spent: 0.8601 sec maximalDeformation=0.0967 minLogLikelihood=4992965.9627 Total time spent: 0.5377 sec maximalDeformation=0.0856 minLogLikelihood=4992565.1591 Total time spent: 0.3703 sec maximalDeformation=0.2802 minLogLikelihood=4991685.9769 Total time spent: 0.6497 sec maximalDeformation=0.3727 minLogLikelihood=4990851.6326 Total time spent: 0.7005 sec maximalDeformation=0.4299 minLogLikelihood=4989292.2391 Total time spent: 0.6234 sec maximalDeformation=0.0558 minLogLikelihood=4989227.1406 Total time spent: 0.8666 sec maximalDeformation=0.1462 minLogLikelihood=4988623.8833 Total time spent: 0.3434 sec maximalDeformation=0.1381 minLogLikelihood=4988427.5693 Total time spent: 0.3750 sec maximalDeformation=0.2492 minLogLikelihood=4987852.7391 Total time spent: 0.6745 sec maximalDeformation=0.2834 minLogLikelihood=4987305.8408 Total time spent: 0.4563 sec maximalDeformation=0.0923 minLogLikelihood=4986496.3694 Total time spent: 0.3953 sec maximalDeformation=0.4959 minLogLikelihood=4984979.2442 Total time spent: 0.3869 sec maximalDeformation=0.6403 minLogLikelihood=4983381.8198 Total time spent: 0.6388 sec maximalDeformation=0.4405 minLogLikelihood=4981984.9514 Total time spent: 0.7790 sec maximalDeformation=0.0000 minLogLikelihood=4981984.9514 Total time spent: 0.0000 sec maximalDeformationApplied: 4.1324 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=1.0000 minLogLikelihood=4979272.9225 Total time spent: 1.5023 sec maximalDeformation=0.3107 minLogLikelihood=4977423.1471 Total time spent: 0.4338 sec maximalDeformation=1.0512 minLogLikelihood=4973218.9498 Total time spent: 0.4320 sec maximalDeformation=0.5114 minLogLikelihood=4971681.6661 Total time spent: 0.6225 sec maximalDeformation=0.3079 minLogLikelihood=4970901.2406 Total time spent: 1.0324 sec maximalDeformation=0.2619 minLogLikelihood=4970119.0201 Total time spent: 0.5934 sec maximalDeformation=0.2282 minLogLikelihood=4969588.6165 Total time spent: 0.9475 sec maximalDeformation=0.3633 minLogLikelihood=4968665.3164 Total time spent: 0.4593 sec maximalDeformation=0.0221 minLogLikelihood=4968586.7308 Total time spent: 2.2266 sec maximalDeformation=0.1603 minLogLikelihood=4968213.4320 Total time spent: 0.3942 sec maximalDeformation=0.1074 minLogLikelihood=4967891.1364 Total time spent: 0.4531 sec maximalDeformation=0.1457 minLogLikelihood=4967641.9802 Total time spent: 0.9538 sec maximalDeformation=0.1070 minLogLikelihood=4967383.7487 Total time spent: 0.5758 sec maximalDeformation=0.0626 minLogLikelihood=4967041.4600 Total time spent: 0.4605 sec maximalDeformation=0.1522 minLogLikelihood=4966600.2359 Total time spent: 0.3761 sec maximalDeformation=0.2736 minLogLikelihood=4966053.8950 Total time spent: 1.1210 sec maximalDeformation=0.2274 minLogLikelihood=4964897.8830 Total time spent: 0.4194 sec maximalDeformation=0.2821 minLogLikelihood=4963439.0791 Total time spent: 0.4251 sec maximalDeformation=0.5705 minLogLikelihood=4961208.8876 Total time spent: 0.4403 sec maximalDeformation=0.0825 minLogLikelihood=4960743.1904 Total time spent: 0.9091 sec maximalDeformation=0.0000 minLogLikelihood=4960743.1904 Total time spent: 0.0000 sec maximalDeformationApplied: 4.6201 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=0.5000 minLogLikelihood=4959911.4972 Total time spent: 1.4805 sec maximalDeformation=0.0572 minLogLikelihood=4959545.3408 Total time spent: 0.3344 sec maximalDeformation=0.4992 minLogLikelihood=4957138.0251 Total time spent: 0.3662 sec maximalDeformation=0.2145 minLogLikelihood=4956401.4287 Total time spent: 0.4801 sec maximalDeformation=0.1421 minLogLikelihood=4955882.4203 Total time spent: 0.8063 sec maximalDeformation=0.1129 minLogLikelihood=4955656.6373 Total time spent: 0.7293 sec maximalDeformation=0.2037 minLogLikelihood=4954801.5981 Total time spent: 0.6768 sec maximalDeformation=0.1524 minLogLikelihood=4954560.3755 Total time spent: 1.9083 sec maximalDeformation=0.0369 minLogLikelihood=4954433.6343 Total time spent: 0.3616 sec maximalDeformation=0.0692 minLogLikelihood=4954314.4909 Total time spent: 0.4321 sec maximalDeformation=0.1294 minLogLikelihood=4954110.0348 Total time spent: 0.7420 sec maximalDeformation=0.5761 minLogLikelihood=4953452.1358 Total time spent: 0.4383 sec maximalDeformation=0.2445 minLogLikelihood=4953215.0229 Total time spent: 0.7136 sec maximalDeformation=0.1743 minLogLikelihood=4952818.0751 Total time spent: 0.6850 sec maximalDeformation=0.5661 minLogLikelihood=4952042.6826 Total time spent: 0.3576 sec maximalDeformation=0.3615 minLogLikelihood=4951301.6549 Total time spent: 0.4553 sec maximalDeformation=0.1585 minLogLikelihood=4951006.8179 Total time spent: 0.4169 sec maximalDeformation=0.2302 minLogLikelihood=4950573.0803 Total time spent: 0.4667 sec maximalDeformation=0.1530 minLogLikelihood=4950323.0437 Total time spent: 0.3605 sec maximalDeformation=0.1310 minLogLikelihood=4949951.9796 Total time spent: 0.3711 sec maximalDeformation=0.0000 minLogLikelihood=4949951.9796 Total time spent: 0.0000 sec maximalDeformationApplied: 2.3574 ======================================================= iterationNumber: 4 EM converged! maximalDeformation=0.5000 minLogLikelihood=4949484.7203 Total time spent: 1.7773 sec maximalDeformation=0.0495 minLogLikelihood=4949256.8886 Total time spent: 0.3532 sec maximalDeformation=0.1908 minLogLikelihood=4948587.2846 Total time spent: 0.7155 sec maximalDeformation=0.1203 minLogLikelihood=4948296.4139 Total time spent: 0.7367 sec maximalDeformation=0.1095 minLogLikelihood=4948062.8993 Total time spent: 0.8235 sec maximalDeformation=0.0302 minLogLikelihood=4948039.2829 Total time spent: 0.6748 sec maximalDeformation=0.0516 minLogLikelihood=4947926.4190 Total time spent: 0.3449 sec maximalDeformation=0.2709 minLogLikelihood=4947587.2773 Total time spent: 0.3565 sec maximalDeformation=0.3071 minLogLikelihood=4947156.3197 Total time spent: 0.4137 sec maximalDeformation=0.2644 minLogLikelihood=4946922.3504 Total time spent: 0.3797 sec maximalDeformation=0.5772 minLogLikelihood=4946610.5674 Total time spent: 0.3661 sec maximalDeformation=0.1349 minLogLikelihood=4946203.4063 Total time spent: 0.3800 sec maximalDeformation=0.0911 minLogLikelihood=4945895.9201 Total time spent: 0.3794 sec maximalDeformation=0.2573 minLogLikelihood=4945153.5907 Total time spent: 0.3617 sec maximalDeformation=0.5422 minLogLikelihood=4944070.9883 Total time spent: 0.3598 sec maximalDeformation=0.3494 minLogLikelihood=4943279.8894 Total time spent: 0.6892 sec maximalDeformation=0.4008 minLogLikelihood=4942294.2331 Total time spent: 0.3480 sec maximalDeformation=0.4237 minLogLikelihood=4941825.4583 Total time spent: 0.3685 sec maximalDeformation=0.1198 minLogLikelihood=4941204.4774 Total time spent: 0.3534 sec maximalDeformation=0.2046 minLogLikelihood=4940632.1613 Total time spent: 0.5393 sec maximalDeformation=0.0000 minLogLikelihood=4940632.1613 Total time spent: 0.0000 sec maximalDeformationApplied: 3.0636 ======================================================= iterationNumber: 5 EM converged! maximalDeformation=0.5000 minLogLikelihood=4939576.2004 Total time spent: 1.1969 sec maximalDeformation=0.2593 minLogLikelihood=4939111.2724 Total time spent: 0.4220 sec maximalDeformation=0.1051 minLogLikelihood=4939010.4211 Total time spent: 0.7778 sec maximalDeformation=0.0578 minLogLikelihood=4938972.3337 Total time spent: 0.3665 sec maximalDeformation=0.1271 minLogLikelihood=4938866.7546 Total time spent: 0.3862 sec maximalDeformation=0.3575 minLogLikelihood=4938539.1804 Total time spent: 0.7233 sec maximalDeformation=0.3180 minLogLikelihood=4938395.4476 Total time spent: 0.6993 sec maximalDeformation=0.1131 minLogLikelihood=4938200.2719 Total time spent: 0.3582 sec maximalDeformation=0.1527 minLogLikelihood=4937936.7201 Total time spent: 0.3626 sec maximalDeformation=0.2324 minLogLikelihood=4937545.6277 Total time spent: 0.3326 sec maximalDeformation=0.0883 minLogLikelihood=4937367.0257 Total time spent: 0.4939 sec maximalDeformation=0.3034 minLogLikelihood=4936979.8630 Total time spent: 0.6668 sec maximalDeformation=0.1199 minLogLikelihood=4936751.9959 Total time spent: 0.3517 sec maximalDeformation=0.1209 minLogLikelihood=4936530.4115 Total time spent: 0.3714 sec maximalDeformation=0.1252 minLogLikelihood=4936330.1353 Total time spent: 0.3798 sec maximalDeformation=0.1688 minLogLikelihood=4936184.9206 Total time spent: 0.3593 sec maximalDeformation=0.1995 minLogLikelihood=4935943.0598 Total time spent: 0.3591 sec maximalDeformation=0.1692 minLogLikelihood=4935619.8188 Total time spent: 0.3747 sec maximalDeformation=0.2447 minLogLikelihood=4935094.1892 Total time spent: 0.3906 sec maximalDeformation=0.2827 minLogLikelihood=4934554.2811 Total time spent: 0.3605 sec maximalDeformation=0.0000 minLogLikelihood=4934554.2811 Total time spent: 0.0000 sec maximalDeformationApplied: 1.7234 ======================================================= iterationNumber: 6 EM converged! maximalDeformation=0.5000 minLogLikelihood=4933966.1319 Total time spent: 1.1963 sec maximalDeformation=0.2042 minLogLikelihood=4933703.0888 Total time spent: 0.3423 sec maximalDeformation=0.0150 minLogLikelihood=4933700.3634 Total time spent: 0.8525 sec maximalDeformation=0.0455 minLogLikelihood=4933690.6611 Total time spent: 0.3450 sec maximalDeformation=0.0216 minLogLikelihood=4933645.9109 Total time spent: 0.3503 sec maximalDeformation=0.1221 minLogLikelihood=4933440.0657 Total time spent: 0.6570 sec maximalDeformation=0.1249 minLogLikelihood=4933300.0490 Total time spent: 0.3465 sec maximalDeformation=0.1703 minLogLikelihood=4933217.2268 Total time spent: 0.3486 sec maximalDeformation=0.1141 minLogLikelihood=4933036.1391 Total time spent: 0.3559 sec maximalDeformation=0.2127 minLogLikelihood=4932883.2139 Total time spent: 0.3673 sec maximalDeformation=0.1619 minLogLikelihood=4932695.6566 Total time spent: 0.3611 sec maximalDeformation=0.1638 minLogLikelihood=4932568.9478 Total time spent: 0.3690 sec maximalDeformation=0.3091 minLogLikelihood=4932479.0890 Total time spent: 0.3617 sec maximalDeformation=0.1528 minLogLikelihood=4932317.1391 Total time spent: 0.3573 sec maximalDeformation=0.1175 minLogLikelihood=4932130.2382 Total time spent: 0.3541 sec maximalDeformation=0.1789 minLogLikelihood=4931879.5709 Total time spent: 0.3539 sec maximalDeformation=0.2034 minLogLikelihood=4931780.1927 Total time spent: 0.4870 sec maximalDeformation=0.2398 minLogLikelihood=4931663.4936 Total time spent: 0.3571 sec maximalDeformation=0.0658 minLogLikelihood=4931616.3674 Total time spent: 0.3544 sec maximalDeformation=0.0796 minLogLikelihood=4931421.7029 Total time spent: 0.3601 sec maximalDeformation=0.0000 minLogLikelihood=4931421.7029 Total time spent: 0.0000 sec maximalDeformationApplied: 1.9506 ======================================================= iterationNumber: 7 EM converged! maximalDeformation=1.0000 minLogLikelihood=4931089.1894 Total time spent: 1.1511 sec maximalDeformation=0.3282 minLogLikelihood=4930946.9014 Total time spent: 0.3373 sec maximalDeformation=0.2099 minLogLikelihood=4930839.2477 Total time spent: 0.3338 sec maximalDeformation=0.1533 minLogLikelihood=4930729.1967 Total time spent: 0.3225 sec maximalDeformation=0.2721 minLogLikelihood=4930560.3832 Total time spent: 0.3639 sec maximalDeformation=0.2807 minLogLikelihood=4930493.1367 Total time spent: 0.7828 sec maximalDeformation=0.0647 minLogLikelihood=4930449.5187 Total time spent: 0.3725 sec maximalDeformation=0.2889 minLogLikelihood=4930388.5091 Total time spent: 0.4040 sec maximalDeformation=0.2688 minLogLikelihood=4930337.2390 Total time spent: 0.3619 sec maximalDeformation=0.0764 minLogLikelihood=4930322.6695 Total time spent: 0.7399 sec maximalDeformation=0.1339 minLogLikelihood=4930249.2433 Total time spent: 0.3758 sec maximalDeformation=0.2481 minLogLikelihood=4930215.5626 Total time spent: 0.5561 sec maximalDeformation=0.1273 minLogLikelihood=4930101.9901 Total time spent: 0.3960 sec maximalDeformation=0.1094 minLogLikelihood=4929986.6875 Total time spent: 0.3951 sec maximalDeformation=0.4091 minLogLikelihood=4929778.0211 Total time spent: 0.4010 sec maximalDeformation=0.0590 minLogLikelihood=4929764.8880 Total time spent: 1.2628 sec maximalDeformation=0.1265 minLogLikelihood=4929690.3257 Total time spent: 0.3943 sec maximalDeformation=0.3183 minLogLikelihood=4929605.3706 Total time spent: 0.3611 sec maximalDeformation=0.0712 minLogLikelihood=4929495.9721 Total time spent: 0.3840 sec maximalDeformation=0.3407 minLogLikelihood=4929258.4855 Total time spent: 0.3758 sec maximalDeformation=0.0000 minLogLikelihood=4929258.4855 Total time spent: 0.0000 sec maximalDeformationApplied: 2.2672 ======================================================= iterationNumber: 8 EM converged! maximalDeformation=0.1598 minLogLikelihood=4928982.5839 Total time spent: 1.5421 sec maximalDeformation=0.0884 minLogLikelihood=4928833.6158 Total time spent: 0.3349 sec maximalDeformation=0.1134 minLogLikelihood=4928699.9160 Total time spent: 0.3395 sec maximalDeformation=0.2077 minLogLikelihood=4928587.5790 Total time spent: 0.3814 sec maximalDeformation=0.1977 minLogLikelihood=4928481.3011 Total time spent: 0.3815 sec maximalDeformation=0.1140 minLogLikelihood=4928359.7018 Total time spent: 0.3519 sec maximalDeformation=0.1907 minLogLikelihood=4928244.6495 Total time spent: 0.3387 sec maximalDeformation=0.1551 minLogLikelihood=4928118.3648 Total time spent: 0.3486 sec maximalDeformation=0.1539 minLogLikelihood=4928078.1460 Total time spent: 0.6877 sec maximalDeformation=0.0417 minLogLikelihood=4928057.2023 Total time spent: 0.3410 sec maximalDeformation=0.0746 minLogLikelihood=4927994.2321 Total time spent: 0.3599 sec maximalDeformation=0.1324 minLogLikelihood=4927920.9966 Total time spent: 0.3592 sec maximalDeformation=0.1165 minLogLikelihood=4927860.4065 Total time spent: 0.3377 sec maximalDeformation=0.1268 minLogLikelihood=4927772.4261 Total time spent: 0.3237 sec maximalDeformation=0.3110 minLogLikelihood=4927707.1281 Total time spent: 0.3518 sec maximalDeformation=0.3017 minLogLikelihood=4927611.4762 Total time spent: 0.3422 sec maximalDeformation=0.2872 minLogLikelihood=4927479.5793 Total time spent: 0.3430 sec maximalDeformation=0.2067 minLogLikelihood=4927339.7412 Total time spent: 0.3304 sec maximalDeformation=0.1392 minLogLikelihood=4927223.4391 Total time spent: 0.3541 sec maximalDeformation=0.4792 minLogLikelihood=4927120.4575 Total time spent: 0.4243 sec maximalDeformation=0.0000 minLogLikelihood=4927120.4575 Total time spent: 0.0000 sec maximalDeformationApplied: 1.6784 ======================================================= iterationNumber: 9 EM converged! maximalDeformation=0.3232 minLogLikelihood=4926925.7839 Total time spent: 1.6692 sec maximalDeformation=0.0822 minLogLikelihood=4926875.0402 Total time spent: 0.3710 sec maximalDeformation=0.0530 minLogLikelihood=4926813.3889 Total time spent: 0.3524 sec maximalDeformation=0.1924 minLogLikelihood=4926680.8490 Total time spent: 0.3614 sec maximalDeformation=0.2612 minLogLikelihood=4926615.4280 Total time spent: 0.3781 sec maximalDeformation=0.1107 minLogLikelihood=4926491.2224 Total time spent: 0.3665 sec maximalDeformation=0.1332 minLogLikelihood=4926380.1391 Total time spent: 0.3769 sec maximalDeformation=0.0550 minLogLikelihood=4926372.3427 Total time spent: 1.0887 sec maximalDeformation=0.0268 minLogLikelihood=4926350.2564 Total time spent: 0.3703 sec maximalDeformation=0.0507 minLogLikelihood=4926304.2354 Total time spent: 0.3688 sec maximalDeformation=0.1569 minLogLikelihood=4926258.8944 Total time spent: 0.3795 sec maximalDeformation=0.0800 minLogLikelihood=4926176.4472 Total time spent: 0.3744 sec maximalDeformation=0.1173 minLogLikelihood=4926069.3543 Total time spent: 0.3605 sec maximalDeformation=0.1826 minLogLikelihood=4925954.1758 Total time spent: 0.3914 sec maximalDeformation=0.2340 minLogLikelihood=4925843.1816 Total time spent: 0.3702 sec maximalDeformation=0.2029 minLogLikelihood=4925739.8497 Total time spent: 0.3623 sec maximalDeformation=0.2431 minLogLikelihood=4925617.5044 Total time spent: 0.3951 sec maximalDeformation=0.1973 minLogLikelihood=4925503.1896 Total time spent: 0.3823 sec maximalDeformation=0.2830 minLogLikelihood=4925434.5352 Total time spent: 0.4088 sec maximalDeformation=0.1777 minLogLikelihood=4925344.4921 Total time spent: 0.4163 sec maximalDeformation=0.0000 minLogLikelihood=4925344.4921 Total time spent: 0.0000 sec maximalDeformationApplied: 1.7670 ======================================================= iterationNumber: 10 EM converged! maximalDeformation=0.3093 minLogLikelihood=4925161.7482 Total time spent: 1.5285 sec maximalDeformation=0.1334 minLogLikelihood=4925093.7142 Total time spent: 0.3563 sec maximalDeformation=0.0566 minLogLikelihood=4925050.8621 Total time spent: 0.3661 sec maximalDeformation=0.0884 minLogLikelihood=4924967.3883 Total time spent: 0.3559 sec maximalDeformation=0.1959 minLogLikelihood=4924870.0735 Total time spent: 0.3495 sec maximalDeformation=0.3035 minLogLikelihood=4924852.3125 Total time spent: 0.3520 sec maximalDeformation=0.0823 minLogLikelihood=4924770.7961 Total time spent: 0.3174 sec maximalDeformation=0.0635 minLogLikelihood=4924723.1632 Total time spent: 0.3300 sec maximalDeformation=0.1236 minLogLikelihood=4924677.2383 Total time spent: 0.3225 sec maximalDeformation=0.0744 minLogLikelihood=4924628.8703 Total time spent: 0.3301 sec maximalDeformation=0.1062 minLogLikelihood=4924569.2673 Total time spent: 0.3247 sec maximalDeformation=0.1022 minLogLikelihood=4924508.5669 Total time spent: 0.3363 sec maximalDeformation=0.1402 minLogLikelihood=4924456.3056 Total time spent: 0.3452 sec maximalDeformation=0.1462 minLogLikelihood=4924411.9980 Total time spent: 0.3482 sec maximalDeformation=0.0818 minLogLikelihood=4924358.9751 Total time spent: 0.3665 sec maximalDeformation=0.1699 minLogLikelihood=4924293.1610 Total time spent: 0.3366 sec maximalDeformation=0.2162 minLogLikelihood=4924221.2580 Total time spent: 0.3559 sec maximalDeformation=0.0931 minLogLikelihood=4924173.0143 Total time spent: 0.3607 sec maximalDeformation=0.0330 minLogLikelihood=4924149.3801 Total time spent: 0.3536 sec maximalDeformation=0.0898 minLogLikelihood=4924093.3267 Total time spent: 0.3567 sec maximalDeformation=0.0000 minLogLikelihood=4924093.3267 Total time spent: 0.0000 sec maximalDeformationApplied: 1.1911 ======================================================= iterationNumber: 11 EM converged! maximalDeformation=0.1683 minLogLikelihood=4923991.9914 Total time spent: 1.6044 sec maximalDeformation=0.0712 minLogLikelihood=4923952.3189 Total time spent: 0.3463 sec maximalDeformation=0.1370 minLogLikelihood=4923929.0298 Total time spent: 0.7078 sec maximalDeformation=0.0671 minLogLikelihood=4923897.1483 Total time spent: 0.3958 sec maximalDeformation=0.0793 minLogLikelihood=4923858.3097 Total time spent: 0.3795 sec maximalDeformation=0.1004 minLogLikelihood=4923823.5745 Total time spent: 0.3761 sec maximalDeformation=0.0760 minLogLikelihood=4923775.0954 Total time spent: 0.3559 sec maximalDeformation=0.1282 minLogLikelihood=4923745.4141 Total time spent: 0.4656 sec maximalDeformation=0.0532 minLogLikelihood=4923713.4979 Total time spent: 0.3762 sec maximalDeformation=0.1591 minLogLikelihood=4923667.9296 Total time spent: 0.4346 sec maximalDeformation=0.0713 minLogLikelihood=4923625.2108 Total time spent: 0.3948 sec maximalDeformation=0.1088 minLogLikelihood=4923579.0373 Total time spent: 0.3881 sec maximalDeformation=0.1609 minLogLikelihood=4923516.6529 Total time spent: 0.4604 sec maximalDeformation=0.2235 minLogLikelihood=4923471.3737 Total time spent: 0.3848 sec maximalDeformation=0.0936 minLogLikelihood=4923405.9382 Total time spent: 0.4483 sec maximalDeformation=0.1193 minLogLikelihood=4923334.1901 Total time spent: 0.3793 sec maximalDeformation=0.1356 minLogLikelihood=4923265.4033 Total time spent: 0.3623 sec maximalDeformation=0.2264 minLogLikelihood=4923199.4973 Total time spent: 0.4527 sec maximalDeformation=0.2463 minLogLikelihood=4923143.8307 Total time spent: 0.3841 sec maximalDeformation=0.1686 minLogLikelihood=4923071.6536 Total time spent: 0.3653 sec maximalDeformation=0.0000 minLogLikelihood=4923071.6536 Total time spent: 0.0000 sec maximalDeformationApplied: 1.6872 ======================================================= iterationNumber: 12 EM converged! maximalDeformation=0.2471 minLogLikelihood=4922954.7950 Total time spent: 1.7916 sec maximalDeformation=0.0764 minLogLikelihood=4922915.4236 Total time spent: 0.3542 sec maximalDeformation=0.0833 minLogLikelihood=4922871.9173 Total time spent: 0.3510 sec maximalDeformation=0.1148 minLogLikelihood=4922831.4541 Total time spent: 0.3557 sec maximalDeformation=0.1269 minLogLikelihood=4922824.0530 Total time spent: 0.9221 sec maximalDeformation=0.0290 minLogLikelihood=4922797.2681 Total time spent: 0.3683 sec maximalDeformation=0.1459 minLogLikelihood=4922777.5362 Total time spent: 0.3563 sec maximalDeformation=0.1331 minLogLikelihood=4922747.0320 Total time spent: 0.3560 sec maximalDeformation=0.0780 minLogLikelihood=4922715.3918 Total time spent: 0.3549 sec maximalDeformation=0.0762 minLogLikelihood=4922688.6463 Total time spent: 0.3401 sec maximalDeformation=0.1198 minLogLikelihood=4922655.1974 Total time spent: 0.3353 sec maximalDeformation=0.1740 minLogLikelihood=4922622.1637 Total time spent: 0.3426 sec maximalDeformation=0.1578 minLogLikelihood=4922611.6702 Total time spent: 0.3496 sec maximalDeformation=0.0529 minLogLikelihood=4922581.2659 Total time spent: 0.3545 sec maximalDeformation=0.1109 minLogLikelihood=4922559.3053 Total time spent: 0.3869 sec maximalDeformation=0.0790 minLogLikelihood=4922533.8277 Total time spent: 0.3542 sec maximalDeformation=0.1770 minLogLikelihood=4922487.5374 Total time spent: 0.3427 sec maximalDeformation=0.3054 minLogLikelihood=4922471.4545 Total time spent: 0.3479 sec maximalDeformation=0.1547 minLogLikelihood=4922424.5650 Total time spent: 0.3626 sec maximalDeformation=0.0748 minLogLikelihood=4922419.4502 Total time spent: 1.3898 sec maximalDeformation=0.0000 minLogLikelihood=4922419.4502 Total time spent: 0.0000 sec maximalDeformationApplied: 1.0496 ======================================================= iterationNumber: 13 EM converged! maximalDeformation=0.1288 minLogLikelihood=4922323.5721 Total time spent: 1.6480 sec maximalDeformation=0.0771 minLogLikelihood=4922294.5665 Total time spent: 0.3617 sec maximalDeformation=0.0725 minLogLikelihood=4922267.1638 Total time spent: 0.3653 sec maximalDeformation=0.1277 minLogLikelihood=4922237.3177 Total time spent: 0.3426 sec maximalDeformation=0.0624 minLogLikelihood=4922211.6702 Total time spent: 0.3632 sec maximalDeformation=0.1453 minLogLikelihood=4922183.3160 Total time spent: 0.3606 sec maximalDeformation=0.0817 minLogLikelihood=4922160.9267 Total time spent: 0.3518 sec maximalDeformation=0.0598 minLogLikelihood=4922140.5226 Total time spent: 0.3569 sec maximalDeformation=0.0516 minLogLikelihood=4922121.8176 Total time spent: 0.3602 sec maximalDeformation=0.0838 minLogLikelihood=4922103.8636 Total time spent: 0.3621 sec maximalDeformation=0.0854 minLogLikelihood=4922085.6062 Total time spent: 0.3731 sec maximalDeformation=0.0774 minLogLikelihood=4922064.0742 Total time spent: 0.3755 sec maximalDeformation=0.0806 minLogLikelihood=4922043.1903 Total time spent: 0.3799 sec maximalDeformation=0.0531 minLogLikelihood=4922025.3641 Total time spent: 0.3871 sec maximalDeformation=0.0462 minLogLikelihood=4922005.1888 Total time spent: 0.3690 sec maximalDeformation=0.0590 minLogLikelihood=4921985.8032 Total time spent: 0.3891 sec maximalDeformation=0.0605 minLogLikelihood=4921964.8965 Total time spent: 0.3709 sec maximalDeformation=0.0794 minLogLikelihood=4921943.3000 Total time spent: 0.3677 sec maximalDeformation=0.0601 minLogLikelihood=4921921.3911 Total time spent: 0.3740 sec maximalDeformation=0.0645 minLogLikelihood=4921897.8161 Total time spent: 0.3879 sec maximalDeformation=0.0000 minLogLikelihood=4921897.8161 Total time spent: 0.0000 sec maximalDeformationApplied: 0.9075 ======================================================= iterationNumber: 14 EM converged! maximalDeformation=0.0478 minLogLikelihood=4921849.2452 Total time spent: 2.0396 sec maximalDeformation=0.0163 minLogLikelihood=4921838.3587 Total time spent: 0.3559 sec maximalDeformation=0.0472 minLogLikelihood=4921824.1692 Total time spent: 0.3403 sec maximalDeformation=0.0424 minLogLikelihood=4921812.7749 Total time spent: 0.3634 sec maximalDeformation=0.0676 minLogLikelihood=4921798.5327 Total time spent: 0.3649 sec maximalDeformation=0.0950 minLogLikelihood=4921782.8183 Total time spent: 0.3662 sec maximalDeformation=0.0828 minLogLikelihood=4921770.2829 Total time spent: 0.3738 sec maximalDeformation=0.0595 minLogLikelihood=4921757.8859 Total time spent: 0.3675 sec maximalDeformation=0.0575 minLogLikelihood=4921739.2774 Total time spent: 0.3736 sec maximalDeformation=0.0921 minLogLikelihood=4921736.6387 Total time spent: 0.3728 sec maximalDeformation=0.0709 minLogLikelihood=4921729.9536 Total time spent: 0.3689 sec maximalDeformation=0.0109 minLogLikelihood=4921727.0815 Total time spent: 1.0228 sec maximalDeformation=0.0173 minLogLikelihood=4921723.4872 Total time spent: 0.3640 sec maximalDeformation=0.0385 minLogLikelihood=4921717.4429 Total time spent: 0.3803 sec maximalDeformation=0.0714 minLogLikelihood=4921709.8759 Total time spent: 0.3915 sec maximalDeformation=0.1451 minLogLikelihood=4921701.1334 Total time spent: 0.7176 sec maximalDeformation=0.2003 minLogLikelihood=4921691.4576 Total time spent: 0.6869 sec maximalDeformation=0.1416 minLogLikelihood=4921668.6915 Total time spent: 0.3691 sec maximalDeformation=0.1267 minLogLikelihood=4921651.1149 Total time spent: 0.3675 sec maximalDeformation=0.0872 minLogLikelihood=4921633.4700 Total time spent: 0.3755 sec maximalDeformation=0.0000 minLogLikelihood=4921633.4700 Total time spent: 0.0000 sec maximalDeformationApplied: 0.9215 ======================================================= VAE lesion model loaded Burn-in 1 times Burn-in 2 times Burn-in 3 times Burn-in 4 times Burn-in 5 times Burn-in 6 times Burn-in 7 times Burn-in 8 times Burn-in 9 times Burn-in 10 times Burn-in 11 times Burn-in 12 times Burn-in 13 times Burn-in 14 times Burn-in 15 times Burn-in 16 times Burn-in 17 times Burn-in 18 times Burn-in 19 times Burn-in 20 times Burn-in 21 times Burn-in 22 times Burn-in 23 times Burn-in 24 times Burn-in 25 times Burn-in 26 times Burn-in 27 times Burn-in 28 times Burn-in 29 times Burn-in 30 times Burn-in 31 times Burn-in 32 times Burn-in 33 times Burn-in 34 times Burn-in 35 times Burn-in 36 times Burn-in 37 times Burn-in 38 times Burn-in 39 times Burn-in 40 times Burn-in 41 times Burn-in 42 times Burn-in 43 times Burn-in 44 times Burn-in 45 times Burn-in 46 times Burn-in 47 times Burn-in 48 times Burn-in 49 times Burn-in 50 times Sample 1 times Sample 2 times Sample 3 times Sample 4 times Sample 5 times Sample 6 times Sample 7 times Sample 8 times Sample 9 times Sample 10 times Sample 11 times Sample 12 times Sample 13 times Sample 14 times Sample 15 times Sample 16 times Sample 17 times Sample 18 times Sample 19 times Sample 20 times Sample 21 times Sample 22 times Sample 23 times Sample 24 times Sample 25 times Sample 26 times Sample 27 times Sample 28 times Sample 29 times Sample 30 times Sample 31 times Sample 32 times Sample 33 times Sample 34 times Sample 35 times Sample 36 times Sample 37 times Sample 38 times Sample 39 times Sample 40 times Sample 41 times Sample 42 times Sample 43 times Sample 44 times Sample 45 times Sample 46 times Sample 47 times Sample 48 times Sample 49 times Sample 50 times thresholding posterior of Lesions with threshold: 0.3 using default intracranial structures to compute sbtiv measure run_samseg complete: 0:59:28.974163