On 5/2/2024 4:03 AM, yunus soleymani wrote:

        External Email - Use Caution        

Hello freesurfers,

I have some questions about the output variables of Freesurfer:

1. In the case of brain volume normalization, do I need to normalize all the volumetric results to the eTIV or just the subcortical volumes?
All volumes. And area too as you note in #4

2. Are there any formulas other than simple division in order to normalize the volumes?
People will sometimes use eTIV as a regressor in the GLM instead of dividing (make sure to normalize so that the scale does not mess up the GLM)

3. How are the .ThckStd values (like FS_R_Insula_ThckStd) calculated? What does the "std" mean here?
standard deviation across vertices

4. I believe that the surface area outputs are also affected by brain size differences in the population. Are there any reference values in the Freesurfer outputs to which surface areas can be normalized?
I just use eTIV

Thank you in advance for your help.

Best regards,
Yunus


--------------------------------------------------------------------------------
Yunus Soleymani
Ph.D. Candidate of Neuroimaging
Tehran University of Medical Sciences
+98 914 526 9298
--------------------------------------------------------------------------------

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer