Hi,

I’m doing volumetric analyses on MR structural data. The problem is that the scanning has been done on different MR machines, as well as with different sequences in some cases. This leads to different absolute values between subjects for volumes and thicknesses when being run through the FreeSurfer segmentation.

My questions regarding this are:

- Is there any way to standardize the results so that the segmentations with different acquisition specs (different MR sequences, MR machine developers) can be comparable?

- I have used v5.3.0 for my segmentations; Is any part of v6.0.0 improved in this regard so that using that version would give more comparable results?

Regards,

Darko Sarovic

Gothenburg University, Sahlgrenska Academy