Hi Gabor,

A good place to start is ADNI’s high-res hippocampal T2 protocol. You can find the details on their website. It’s a coronal, anisotropic acquisition of a slab covering the hippocampus (0.4mm in plane, 2mm thickness, 25-30 slices). I’ve been playing a bit with more isotropic acquisition myself, but haven’t drawn any conclusions yet.

Cheers,

/Eugenio

PS: 1mm MPRAGE is good.

-- 

Juan Eugenio Iglesias

ERC Senior Research Fellow

Translational Imaging Group

University College London

http://www.jeiglesias.com

http://cmictig.cs.ucl.ac.uk/

From: <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Gabor Perlaki <petzinger.gabor@gmail.com>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, 4 December 2017 at 10:20
To: freesurfer <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] MRI protocol for hippocampal subfield segmentation

I've two questions regarding hippocampal subfield segmentation:

1, Is there any article or other document which containes an optimal T2 protocol with detailed sequence parameters for hippocampal subfield segmentation? (eg. BW, echo time, repetition time, FOV, echo train, paralell imaging on/off, ...) We have a Siemens Prisma 3T scanner.

2, For T1, we use the suggested MPRAGE protocol by Andre (1mm*1mm*1mm). Is it OK or do we need a special protocol?

Thank you,

Gabor