Dear experts,

I would like to run mri_glmfit in a group analysis. However, I met the following error when I added the medicationload as variable in my fsgd file.

Since I have 305 subjects and only 75 of these have medication load, it seems to this variable includes too many zero. Just I guess.

The error:

ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08\

\

\

--------------------------------\

-------- ERROR: READ THIS -----------------\

--vvvvvvvvvvvvvvvvvvvvvvvvvvvvvv-----\

Possible problem with experimental design:\

Check for duplicate entries and/or lack of range of\

continuous variables within a class.\

If you seek help with this problem, make sure to send:\

  1. Your command line:\

    mri_glmfit --y lh.volume.BDHC3Study.10.mgh --fsgd FSGD/BDHC3Study.fsgd --C Contrasts/HC3-BD3.mtx --C Contrasts/BD3-HC3.mtx --surf fsaverage lh --cortex --glmdir lh.volume.BDHC3Study.10.glmdir \

  2. The terminal output of this program (ie, everything it prints to the screen)\

  3. The FSGD file (FSGD/BDHC3Study.fsgd)\

  4. The design matrix lh.volume.BDHC3Study.10.glmdir/Xg.dat\

Attempting to diagnose further \

SumSq: Min=6.368664 (col 8), Max=16.261612 (col 7)\

... could not determine the cause of the problem\

--^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^----\

}

 

I attached my terminal output, fsgd file, and design matrix

 

Thanks

 

Yuan