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Angel Hammond
Research Specialist
Center for Healthy Minds
University of Wisconsin-Madison
Dear Angel,
It’s hard to tell without seeing the segmentation in 3D. Would you mind sharing, please?
Cheers,
/Eugenio
Juan Eugenio Iglesias
Senior research fellow
CMIC (UCL), MGH (HMS) and CSAIL (MIT)
From:
<freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Angel Hammond <ahammond3@wisc.edu>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, August 10, 2020 at 10:11
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] Reposting a Question RE: Hippocampal/Amygdala subfield segmentation - Medial Nucleus Errors
External Email - Use Caution
Hello Freesurfer Experts,
I wanted to re-post a portion of a question that a previous team member posted on June 20th, 2019 (See: Reposting a Question RE: Hippocampal/Amygdala subfield segmentation - Anterior Amygdala Area / Medial Nucleus Errors)
We have visually checked 116 subjects that have been processed using
Freesurfer's latest hippocampal/amygdala subfield segmentation
algorithm (Development version 20180518 <https://surfer.nmr.mgh.harvard.edu/fswiki/HippocampalSubfieldsAndNucleiOfAmygdala>)
and came across a few cases that had questionable segmentation. The T1s had were processed using
FS 5.3, and we used the command "segmentHA_T1.sh" from the latest Dev
version.
-We have come across about 5 subjects' medical nuclei masks that are located in the Putamen region (more superior/detached from the rest of the amygdala) on one side of the brain (in some cases just the right side, in other cases just the left side). In all of the other subjects, we don't see that same detached looking segmentation into the putamen on one side as these few show. I will attach screenshots to show this.
-I have checked the aseg for these subjects as suggested in the previous question, and the hippocampus, amygdala, and putamen all look fine there. I have also checked the output volumes for the medial nucleus of these subjects and the numbers all look fine.
-So, my main question is: If the placement of the medial nucleus is wrong in the segmentation (detached/in the putamen as shown) but the aseg looks correct, can we still use those values reliably?
Thank you!
Angel Hammond
Research Specialist
Center for Healthy Minds
University of Wisconsin-Madison