Hi,

We are experimenting with statistical methods for analyzing cortical thickness differences in a case/control study. After doing the cortical reconstructions and running mris_glm, we will have the significance (p-value) of the t-ratio of the contrast between case and control. What we want to do is first apply some spatial smoothing to the p-values, and use a false discovery rate controlling method on the resulting smoothed p-values to find an appropriate significance level.

We can run mris_glm, save the output in bfloat format, and load into Matlab using 'fread'; no problems.

What we are lacking is a description of the topology of the vertices, and the mapping from the vector of floats to this topology. I assume a triangulation implies a 6-connect structure. Correct? Assume the vertices are numbered 1:163842 (as in the output of mris_glm --sigt), which vertices are neighbors (what are the six neighbors of vertex 100) ?? Are distances between neighbors (nearly) constant, or do they vary???

Very much appreciative of your reply,

+glenn

-- 

I want to go farther, farther!

          A. E. L.

>  Glenn Lawyer                   <
>  Instituttgruppe for psykiatri  <
>  Postboks 1130 Blindern         < 
>  0318 Oslo                      <
<  http://folk.uio.no/davidgl     >
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