Are you getting a 0.8mm isotropic T2w or FLAIR? You would probably get better mileage out of a different type of scan that can help exclude dura and blood vessels if you aren’t already getting one. Also what coil are you using? I might prefer a TI=1000ms simply because it spreads the CSF, GM, and WM histogram peaks out a little more evenly, whereas 1060 will have GM and WM closer together than GM and CSF.

From: <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Alessandra Macbeth <alessandramacbeth@gmail.com>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Wednesday, March 7, 2018 at 1:29 PM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] Collecting 2 T1s Best?

Hi there,

I know in the past, it was recommended to acquire 2 T1 scans so that they could be averaged for better SNR, etc. in order to improve cortical thickness and surface area measurements. Is this still the recommendation? We have a few extra minutes in our scanning protocol and are debating whether to include a 2nd T1.

Our parameters are: MPRAGE with .8mm^3 voxel size, slice thickness of .8, FA = 8 degrees, TR = 2400ms, TE = 2.72ms, TI = 1060ms.

Best,
Alessandra

Alessandra Macbeth, M.A.

Doctoral Candidate - Department of Psychology

University of California, Riverside