After processing dozens of subjects through tracula I have found some subjects with tracts that are one voxel along the entire tract, for example the forceps major. After reviewing the data I believe the bvecs files are pointing the correct direction, I believe the registration between the T1/freesurfer segmentation and DTI is reasonably good (registration was performed with bbr), at least the anat_brain_mask-vent.bbr and dtifit_FA are reasonable and cortex.bbr and lowb_brain seem reasonably well registered. The brain extraction does look poor in that a large chunk of posterior skull remains in the anat_brain_mask-vent.bbr image but the as the registrations, segmentations and parcellations look OK I believe this isn&#39;t the cause of my problems.<br>
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<br>I do see one issue: the registration between the dtifit_FA.bbr and fmajor_PP_avg33_mni_bbr_logprior_0 images. Sections of the logprior volume are entirely in the lateral ventricles of the DTI data. Please see attached jpg. This subject  large lateral ventricles and I am wondering if such subjects can be run successfully in tracula. Much thanks for any suggestions.<br>



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