Hi,

I can't help you with ANOVA (never done that), but you can
- either subtract the two time points and then do a regular group analysis
https://surfer.nmr.mgh.harvard.edu/fswiki/PairedAnalysis

- or run a Linear mixed effects model
https://surfer.nmr.mgh.harvard.edu/fswiki/LinearMixedEffectsModels 


The first option is good if you always have 2 time points (zero or close to zero drop outs) and the time delta is the same between the two time points for all subjects. The second is a powerful analysis that can deal with drop outs, different time deltas etc.

Best, Martin

On 02/29/2016 01:54 PM, Universidad de Deusto wrote:
Dear FS Experts,

I'm interested in performing Repeated Measures ANOVA 2x2. I have 2 groups and two times (pre and post treatment).
I have checked the tutorial for repeated measures anova and previous emails:
http://www.mail-archive.com/freesurfer%40nmr.mgh.harvard.edu/msg45703.HTML
http://www.mail-archive.com/freesurfer%40nmr.mgh.harvard.edu/msg45650.HTML

However, it is not clear to me, which steps I have to follow to create the matrix and obtain the results for groupxtime effect.

I would be very grateful if someone could help me with this analysis,

Thank you in advance,

Best Regards


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-- 
Martin Reuter, PhD
Assistant Professor of Radiology, Harvard Medical School
Assistant Professor of Neurology, Harvard Medical School
A.A.Martinos Center for Biomedical Imaging
Massachusetts General Hospital
Research Affiliate, CSAIL, MIT
Phone: +1-617-724-5652
Web  : http://reuter.mit.edu