I would like to know which are the best ways to normalize the VOI's to intracranial volume.

Also, what is the variable BrainSegVol-to-eTIV in aseg? Is it a scaling factor?

Does freesurfer segmentation provide a scaling factor?

Best regards, Carolina

Carolina M Rimkus, MD, PhD

Neuroradiologist

Department of Radiology, Faculty of Medicine, University of São Paulo-SP, Brazil