Hi Doug,

Thanks for the reply. I'm not sure i understand how to solve it.
Are you suggesting to re-run bbregister using the --init-reg option and the register.dat files  that were previously created for the badly-registered subjects?

Joana


2011/10/17 Douglas N Greve <greve@nmr.mgh.harvard.edu>
Those almost surely failed because of a bad initialization. You can usually tell this by looking at the first value in the mincost file. For these, the mincost is something like .9. The mincost will be a value bet 0 and 1.1, with 0 being perfect. Looks at your good subjects to get an idea of what range to expect for well-registered subjects. You should be able to use the registrations you created as input to bbregister (with the --init-reg option), and bbregister should do fine after that.
doug

Joana Braga Pereira wrote:
Hi Doug,

I made quite a few changes, including translations and rotations (not scaling changes), to 10 out of 24 subjects.

Here are a few of the bbregister log.files from subjects in which the registration didn't go well.

Thanks for the help!

Joana

2011/10/17 Douglas N Greve <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>>


   Hi Joana, how big were the changes that you made? Sometimes the
   initialization routine won't get it close enough, then bbregister
   fails. Can you send the bbregister log file?
   doug

   Lilla Zollei wrote:


       Even though it is not ideal, manual adjustments can be useful.
       I would use manual registration in a small number of cases
       though. If most of your data requires it, I would try to play
       with the automatic registration parameters more.

       --Lilla

       On Sun, 16 Oct 2011, Joana Braga Pereira wrote:

           Dear Lilla and Ed,
           Thanks a lot for your suggestions, they were really really
           helpful!

           I did the analyses as you suggested. After bbregister i
           checked the results with tkregister2 and saw that most
           subjects were well coregistered. However in a few of them
           my lowb images were out of place with respect to the
           target and so i made manual adjustments using bbregister
           interface tools..

           I was just wondering whether this is the normal procedure
           as manual adjustments can be quite subjective and i would
           prefer not to introduce such a bias in the analyses.

           Thanks a lot for your valuable help!

           Joana

                        2011/10/15 Ed Gronenschild <ed.gronenschild@np.unimaas.nl
           <mailto:ed.gronenschild@np.unimaas.nl>>

                Dear Joana,
           Two things:

           1.
           You should be very careful to use fslswapdim since it may
           result
           in an unintended left-right flipping. It's better to use
           fslreorient2std.
           2.
           The tool dt-recon computes the coregistration of the lowb
           volume to
           the anatomical volume, see register.dat.
           You can then use the following to coregister FA:

           mri_vol2vol --reg  register.dat --mov fa.nii --o
           fa-ana.nii -targ subject/mri/T1.mgz

           where "subject" is the output folder generated by the
           recon-all command.
           You should not forget to set the global variable SUBJECTS_DIR

           Cheers,
           Ed

           On 14 Oct, 2011, at 18:00,
           freesurfer-request@nmr.mgh.harvard.edu
           <mailto:freesurfer-request@nmr.mgh.harvard.edu> wrote:


           Dear Bruce and Anastasia,

           Thanks for the quick reply!

           I tried the bbregister as you suggested but when i
           visualize the target and
           dti image they don't look registered at all.

           This is the comand i used:

           bbregister --s CN01 --mov
           /home/joana/FA/CN01/dti_FA.nii.gz --reg
           /home/joana/FA/CN01/register.dat --init-fsl --dti
           --template-out
           /home/joana/FA/CN01/template.nii.gz --fslmat
           /home/joana/FA/CN01/flirt.tmx

           I tried to use the bbregister tools to align them but I
           didn't get very
           far...

           Did i miss something?

           I read in another mail something about using the
           register.dat created in
           bbregister and do mri_label2vol but i'm not sure how to do it.

           Thanks,

           Joana



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   --     Douglas N. Greve, Ph.D.
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MGH-NMR Center
greve@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 Fax: 617-726-7422

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