Hi,

I am still struggling to examine differences in thickness using the command line stream for my two groups after controlling for age and sex. I get the following error when running the command line:

ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08
--------------------------------
Possible problem with experimental design:
Check for duplicate entries and/or lack of range of
continuous variables within a class.
If you seek help with this problem, make sure to send:
  1. Your command line:
    mri_glmfit.bin --y CAA_CTRL_RH.thickness.10.mgh --fsgd 
CAA_CTRL_RH_Age_Sex.fsgd --C Contrasts/CAA-CTRL_Age_Sex.mtx --surf fsaverage rh 
--cortex --glmdir CAA_CTRL_RH_Age_Sex_Unix.glmdir
  2. The FSGD file (if using one)
  3. And the design matrix above
Attempting to diagnose further
SumSq: Min=0.000000 (col 5), Max=611.699463 (col 4)
 The scale is much different between columns 5 and 4, you may want to
 normalize by subtracting the mean and dividing by the standard deviation.
Column 5,  all values are 0
Column 6,  all values are 0
Columns 5 and 6 are the same

My design matrix is:
1 -1 0 0 0 0 (Examining difference in thickness after controlling for effects 
of age and sex)

Iâ€™ve also attached the FSGD file that Iâ€™ve been using. Please let me know if there is something wrong with the file (although I have used a similar file without the covariates and did not have any issues).