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Hi Experts,

 

I am using bbregister to align functional data to anatomical space. I have been using the bbregister command with a combination of different flags. However, there appears to be varying levels of poor registration. 

 

The first command I used included flags for a whole brain reg image and the --init-header flag. As you can see in the attached image titled tkreg 1, there is a misalignment.

 

bbregister --s PPT_1x --feat  /Data/PMA_retinoScans/PPT_1x/run1_pre_processed_functional.feat/ --int  Data/PMA_retinoScans/PPT_1x/WholeEPI.nii.gz --init-header

 

I then removed the –int (whole brain reg image) flag. Again the registration is massively misaligned (image titles reg1)

 

bbregister --s PPT_1x --feat  /Data/PMA_retinoScans/PPT_1x/run1_pre_processed_functional.feat --init-header

 

I then removed the –init-header flag. Again poor registration (image titled reg 2)

 

Then I removed both flags. This was the best registration (see attached image titled reg 3), but even this still looks a little bit off to me. You can see that around the occipital lobe, there white matter isn't aligned very well.

 

bbregister --s PPT_1x --feat /Data/PPT_1x/run1_pre_processed_functional.feat/

 

Can anyone give me any advice on this? I really am unsure as to which why these flags failed to aid registration. I have 3 other participants from a different dataset for which the bbregister pointing to the feat directory and the –init-header flag worked perfectly.

 

Any advice would be great.

Thanks in advance,

Mason

 

 

Mason T Wells, MSc

PhD student

School of Optometry and Vision Sciences

& Cardiff University Brain Research

Imaging Centre (CUBRIC), School of Psychology

Cardiff University

Cardiff   

CF24 4HQ

UK

 

EmailWellsMT1@cardiff.ac.uk

Tel02920 879628

WebCardiff University webpage

Mason T Wells, MSc

Myfyriwr PhD

Yr Ysgol Optometreg a Gwyddorau’r Golwg

& Canolfan Ymchwil Delweddu’r Ymennydd Prifysgol Caerdydd (CUBRIC), Yr Ysgol Seicoleg

Prifysgol Caerdydd

Heol Maindy

Caerdydd   

CF24 4HQ 

DU

 

E-bostWellsMT1@caerdydd.ac.uk

Ffôn02920 879628