Hi Pietro,
I think you should try redoing the control points from scratch, but with fewer control points and sparser placement.  Currently you have 198 control points tightly packed in only a couple regions.  Furthermore, there is one control point at 128, 128, 128 which is right in the thalamus which should not be there, maybe an accidental click?

Take a look at the placement of the control points in the snapshots on this tutorial page:
https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/ControlPoints_freeview

If you compare the norm.mgz volumes before/after editing, you will notice the extreme hyper-intense wm (130+) in the temporal lobes after adding control points and rerunning.  The norm.mgz is passed to mri_pretess to create the wm.mgz.  You can see there is overlap between the hyper-intense voxels on the norm and the voxels not being included in the wm mask, which leads to major errors in the wm surface.
-Louis

On Fri, 15 Nov 2013, pietro de rossi wrote:

Good morning Dr Vinke,
did you have the chance to take a look at the subject I uploaded a few days ago?

thanks again.

Kind regards,

Pietro

--
Pietro De Rossi, MD
-------------------------------------
Sapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento NESMOS (Neuroscienze, Salute Mentale, Organi
di Senso), Ospedale Sant'Andrea, Via di Grottarossa 1035-1039, 00189 Roma

NESMOS Department (Neurosciences, Mental Health and Sensory Functions), School of Medicine and Psychology, Sapienza
University, Sant’Andrea Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy

Laboratorio di Neuropsichiatria, Dipartimento di Neurologia Clinica e Comportamentale, IRCCS Fondazione Santa Lucia, via
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