what software did you use? Are you sure you are using the same model as
qdec uses?
On 06/25/2014 11:03 AM, Emma Thompson wrote:
> Thanks Doug, yes I did control for age in both instances.
>
>
> On Wed, Jun 25, 2014 at 10:14 AM, Douglas N Greve
> <mailto:Freesurfer@nmr.mgh.harvard.edu>> <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>> wrote:
>
>
> Your interpretation is right (ie, controls > patients for
> red/yellow/orange). When you compared the two groups in your separate
> analysis, did you control for age?
> doug
>
>
> On 06/24/2014 02:19 PM, Emma Thompson wrote:
> > Hi Freesurfers,
> > I am reposting this as my last email bounced.
> >
> > I have conducted a DODS analysis in qdec with group (controls vs
> > patients) set as my fixed factor and age as a nuisance variable to
> > determine if my groups differ in cortical thickness. Controls were
> > added first in the .levels file followed by patients. When I
> view the
> > results in the display window for "do controls differ from
> patients in
> > cortical thickness" I see a significant cluster for the caudal
> > anterior cingulate, denoted by a red-orange blob and a positive
> > t-value. I'm wondering if this simply means that controls had
> greater
> > cortical thickness compared to patients after controlling for
> age? The
> > reason I ask is that I'm a little confused since when I created
> an ROI
> > for this cluster using tksurfer and then extracted the means and
> sd, I
> > see that the patients actually have larger means than the controls,
> > the opposite of my interpretation of the results presented by
> the qdec
> > display. Furthermore, if I extract the means and sds for the entire
> > caudal anterior cingulate using the aparc file, I get means that are
> > larger in controls, compared to patients, which seems consistent
> with
> > qdec. Any ideas? Thanks for all the help.
> >
> >
> > _______________________________________________
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> > Freesurfer@nmr.mgh.harvard.edu
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer> greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
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Fax: 617-726-7422
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