bbregister is more sensitive to the smoothing in the PET images. This can create a confound between atrophy and registration. bbregister should only be used on non-smoothed data.

On 5/1/2024 5:06 AM, Ruben Dörfel wrote:

External Email - Use Caution

Hi FreeSurfer Team,

I am currently using PETSurfer to analyze FDG data. Following the guide MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be https://surfer.nmr.mgh.harvard.edu/fswiki/PetSurfer, it is suggested that you use mri_coreg to register PET and MRI images. However, I was wondering whether bbregister might not be the more appropriate tool to use, especially in a case like FDG, where we have a lot of uptake in the brain.

Best regards,

--

Ruben Dörfel, MSc
PhD Student

Center for Psychiatry Research
Karolinska Institutet

Neurobiology Research Unit
Copenhagen University Hospital, Rigshospitalet
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