Hi Jose

usually we don't need multiple averages (or study specific ones), which
simplifies things considerably. Is there a reason you think you need one?
We intentially use the gray/white boundary for this reason, which is
insensitive to any possible cortical atrophy.

cheers
Bruce

On Mon, 18 Feb 2019, Laboratorio de
Neurociencia Funcional wrote:

>
>         External Email - Use Caution        
>
> Dear all,
>
> I am planning to run separate regression analysis with cortical thickness in two very different
> populations (young and elderly subjects). Depending on results, it may happen that I am interested
> in comparing regression slopes between the two groups. My question is: should I build one average
> subject for each within-group regression analysis (one for young and another for elderly), and
> another different average subject merging all subjects of the two samples to compare regression
> slopes? Or I should preferably use only one average subjects with all subjects in all within and
> between regression analysis?
>
> Many thanks in in advance.
>
> Best regards,
> Jose
>
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