Dear Dr Greve,

Kindly, I wanted to know why "mri_coreg" apples smoothing during registration. e.g.

mri_coreg --s subject --mov template.nii.gz --reg template.reg.lta

Are there any effects on the accuracy of smoothing if I turn off this default feature (specifically in pet surfer pipeline).

mri_coreg --s subject --mov template.nii.gz --reg template.reg.lta --no-smooth

Thank you for any clarification

John