Dear FreeSurfers,



we have MR scans from a group of healthy subjects (about 40, equal

number of males and females, age range 25 to 65 years), who were scanned

at two time points (about four months separation). In between they

experienced exposure to a condition that might or might not influence

cortical thickness or other morphometric measures. From other studies we

have a large number of healthy controls in the same age range. The

difference is that they were scanned only once and were not exposed to

any special condition.



We want to find out where cortical thickness changes significantly

stronger in our subjects than expected from the controls for normal

aging. We know how to do that for the averages over cortical

parcellations and sub-cortical segmentations as reported in the

aseg.stats and aparc.stats.



Is it possible to use qdec to do the same thing vertex-wise? The

symmetrized percent changes have been calculated already from

FreeSurfer's longitudinal stream (long_mris_slopes). How can we feed the

information about the locally expected change rate (and maybe even its

variability) into qdec?



Thanks,

Christian Rummel





_____________________________________________________________________



Christian Rummel (PhD)



Support Center for Advanced Neuroimaging (SCAN)

University Institute for Diagnostic and Interventional Neuroradiology

Inselspital, 3010 Bern, Switzerland



Tel. 0041 31 6328038

Fax 0041 31 6324872

crummel@web.de



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