Hi:

  Why I got a big ICV difference between MPRAGE of the same patient (2019: 1775887.317631, 2020: 1566398.53576 mm3), one-year difference acquisition, and the same MRI Skyra 3T equipment? I used freesurfer 5.1.0 on the same computer, and operating system in both cases...

  I reviewed the coregistration to MNI305 and it is reasonably good in both cases...

  The case was reviewed by an expert neuroradiologist, and she does not consider that there is a significant visual difference between both sizes.

  Sincerely

Gonzalo Rojas Costa