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Hi Doug,
Thanks for the reply. There's a good chance that the data will ultimately be used for a pooled analysis of data acquired across multiple sites at some point. In the relatively recent past, we've used the online-corrected scan without applying post hoc correction. When planning a new study, the staff here at BU warned against using that scan. Do you know why there is pushback on using the online corrected scan? 

Best,
Jason



On Mon, Aug 3, 2026 at 11:50 AM Douglas N. Greve <dgreve@mgh.harvard.edu> wrote:
Hi Jason, it depends on what you are going to use it for. If you have a situation where distortion correction is going to be important at some point (eg, multi site study), then I would probably use the distortion corrected version. It is possible to apply it post hoc, but it is a pain. In the end, I don't think it will make much of a difference.


On 7/28/2026 12:44 PM, Jason Tourville wrote:

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Hi Freesurfer supporters,
When collecting T1-weighted MEMPRAGE for input to FS recon, is it better to use the online distortion corrected RMS volume? Or the RMS volume without correction? 

Best,
Jason

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