Hi Sabin,

there is no tutorial, but a detailed description here (with examples):
https://surfer.nmr.mgh.harvard.edu/fswiki/LinearMixedEffectsModels

the long.qdec table is just a text file and described, for example, here:
https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/LongitudinalTutorial_freeview#LongitudinalQDECTable

The trickiest part for you will be to setup the model and that depends on the analysis you want to do (what co-variates to include, are some time varying, fixed and mixed effects). As that can get more involved we recommend to include a bio-statistician or read up on the statistics.

This is a good book (but you need some math background):
http://www.hsph.harvard.edu/fitzmaur/ala/

Best, Martin

On 01/03/2014 10:07 AM, sabin khadka wrote:

Hi all,

I was just wondering if there is a tutorial or example on how to use linear mixed effect model toolbox for longitudinal analysis.

I already processed my structural images with longitudinal processing pipeline from freesurfer. I want to do group analysis where I have 4 groups with N~20-30 on each group for time T1 and T2 scans in duration of ~2 years. I am kind of in confusion on how to proceed like making qdec.table.dat and contrast matrix and all.

Thanks for help!!!!

--

Cheers,

Sabin
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Martin Reuter, Ph.D.
Assistant in Neuroscience - Massachusetts General Hospital
Instructor in Neurology   - Harvard Medical School
MGH / HMS / MIT

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