I created a registration template and atlas from scratch could I input that in the interhemispheric registration analysis?

On Oct 24, 2016 5:03 PM, "Douglas N Greve" <greve@nmr.mgh.harvard.edu> wrote:

It would depend on how big the ROI is to begin with. Do you know that we
have our own interhemispheric analysis that might be better for this?
Check out

http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi

On 10/24/2016 12:33 PM, Daya P wrote:
> Hi Bruce,
>
> I drew ROIs on an initial subject and then after registering all other
> subjects to the initial one, used mri_label2label to map the ROIs from
> the initial subject to subsequent ones.
> I am interested in looking at asymmetry between left and right regions.
>
> I had two concerns, one that the ROIs have different # vertices on
> different subjects, but as you mentioned the nonlinear process makes
> sense, since each subject does not have the exact same brain size and
> curvature.
>
> Another concern was that the ROIs on the left and right hemisphere in
> a subject do not have the exact same number of vertices. Would a
> difference of 10 vertices max bias results?
>
> Thank you for your help,
>
> Daiana R. Pur
> Research Assistant
> Canadian Surgical Technologies & Advanced Robotics
> Brain and Mind Institute
> Western University
> London, ON, N6A 5B7
> Canada
>
> On Mon, Oct 24, 2016 at 12:09 PM, Bruce Fischl
> <fischl@nmr.mgh.harvard.edu <mailto:fischl@nmr.mgh.harvard.edu>> wrote:
>
> Hi Daiana
>
> yes, that is to be expected given the nonlinear nature of the
> cross-subject registration. It shouldn't bias things, although
> you'll need to give us more details if you want a more definitive
> answer.
>
> cheers
> Bruce
>
>
>
> On Mon, 24 Oct 2016, Daya P wrote:
>
> Hi All,
>
> My question is about using mri_label2label. When mapping the
> labels from one
> subject to another the number of vertices of each ROI is
> different. Is that
> something to be expected?
>
> How much of a difference does a number of vertices of 50
> compare to 40 have
> on measures like thickness, grey matter and surface area?
>
> I would really appreciate some help
>
> Thank you,
>
> Daiana R. Pur
> Research Assistant
> Canadian Surgical Technologies & Advanced Robotics
> Brain and Mind Institute
> Western University
> London, ON, N6A 5B7
> Canada
>
>
>
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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
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