External Email - Use Caution        

Thank you Bruce for your reply and the helpful information. Our data never went through Analyze format (we converted the data from dcm > NIFTI using mricron). FreeView reads the data appropriately (confirmed by attaching a Vitamin D pill to one of our subject's right side).  

Thanks again;
--Meena

On Fri, Dec 14, 2018 at 5:59 PM Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
when you bring it up in freeview does it properly show left and right? If
it ever went through analyze as a format you will have lost the
information that lets us distinguish left from right

cheers
Bruce
On Fri, 14 Dec 2018,
Geha, Paul wrote:

> It is NIFTI format.  
> ——————————————————
> Paul Geha, MD
> Assistant Professor of Psychiatry
> Yale School of Medicine
> Assistant Fellow, The John B. Pierce Laboratory
> Email: paul.geha@yale.edu
> Tel:(203)903-4334
>
>
>
>       On Dec 14, 2018, at 10:53 AM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:
>
> what is your input data format?
> On Fri, 14 Dec 2018, Geha, Paul wrote:
>
>       Dear Bruce,
>
>       Thank you for your reply.
>
>       However, we are obtaining an odd result with FreeSurfer when we examine the volume
>       of the left and right accumbens.  In the UK  BioBank data >20K subjects freesurfer
>       segmentations the left accumbens is clearly significantly larger than the right
>       accumbens (https://na01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fbiobank.ctsu.ox.ac.uk%2Fcrystal%2Fla
> bel.cgi%3Fid%3D110&amp;data=02%7C01%7Cpaul.geha%40yale.edu%7C6fe7514e6a064d661e6608d661dc40ef%7Cdd8c
> bebb21394df8b4114e3e87abeb5c%7C0%7C0%7C636803995945018317&amp;sdata=Iq5%2FMtaNTPUbuvdXnDnRVGPV6NOnMN
>       MMSLiAGyXq734%3D&amp;reserved=0<https://na01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fbiobank.ctsu.ox.ac.uk%2Fcrystal%2Fl
> abel.cgi%3Fid%3D110&amp;data=02%7C01%7Cpaul.geha%40yale.edu%7C6fe7514e6a064d661e6608d661dc40ef%7Cdd8
> cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C636803995945018317&amp;sdata=Iq5%2FMtaNTPUbuvdXnDnRVGPV6NOnM
>       NMMSLiAGyXq734%3D&amp;reserved=0>). Also, the attached paper used freesurfer and
>       found left accumbens > right.  In our hands, and in  2 different data sets
>       collected in two different sites,  we obtain the opposite with FreeSurfer (right
>       accumbens > left accumbens).
>
>       Furthermore, when we segment these same data sets with FIRST from FSL we do obtain
>       Left accumbens > right Accumbens in both data sets in agreement with the
>       literature.
>
>       Any help in solving this discrepancy is much appreciated.
>
>       Regards,
>       Paul
>       ——————————————————
>       Paul Geha, MD
>       Assistant Professor of Psychiatry
>       Yale School of Medicine
>       Assistant Fellow, The John B. Pierce Laboratory
>       Email: paul.geha@yale.edu
>       Tel:(203)903-4334
>
>
>
>             On Dec 13, 2018, at 3:49 PM, Bruce Fischl <fischl@nmr.mgh.harvard.edu>
>             wrote:
>
>             Hi Meena
>
>             it shouldn't. We reorient everything to radiological
>
>             cheers
>             Bruce
>             On Thu, 13 Dec 2018, Meena M. Makary wrote:
>
>                          External Email - Use Caution
>                   Hi;
>                   I am wondering if the orientation of the input data to
>                   recon-all (i.e. Neurological Vs. Radiological)
>                   produces different results in terms of laterality (right
>                   vs. left)?
>                   Thanks;
>                   --Meena
>                   —
>                   Meena M. Makary, Ph.D.
>                   Assistant Professor | Cairo University
>                   Postdoctoral Fellow | Yale University School of Medicine
>                   Postdoctoral Associate |  The John B. Pierce Laboratory
>                   Postdoc Committee Chair | The John B. Pierce Laboratory
>                   Career Development and Mentoring Manager Elect | OHBM
>                   Student and Postdoc SIG
>                   290 Congress Avenue, New Haven, CT 06519
>                   +1 (475) 731-5592
>
>
>
>
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--

Meena M. Makary, Ph.D.
Assistant Professor | Cairo University 
Postdoctoral Fellow | Yale University School of Medicine
Postdoctoral Associate |  The John B. Pierce Laboratory
Postdoc Committee Chair The John B. Pierce Laboratory
Career Development and Mentoring Manager Elect OHBM Student and Postdoc SIG

290 Congress Avenue, New Haven, CT 06519