Hi there,

Would it be problematic if N4BiasFieldCorrection were to be applied to the T1w before processing it in the standard recon-all pipeline?

The reason is because we want and use the same T1w in other pipelines which require brain extraction and linear and nonlinear registrations, such as what would be for rsFMRI network analysis. Applying N4BiasFieldCorrection to the raw T1w would be quite useful in that regard. 

Something that would be similar to what is done for the HCP or UK Biobank pipelines. 

Thanks for your help!

Nárlon Cássio

Nárlon Cássio Boa Sorte Silva PhD (He, Him, His)
CIHR and MSHR BC/PARF Postdoctoral Research Fellow
Aging, Mobility, and Cognitive Health Lab
Djavad Mowafaghian Centre for Brain Health
Department of Physical Therapy, Faculty of Medicine
University of British Columbia
Vancouver, Canada
Twitter: @BoaNarlon