Hi Freesurfer Experts,

I am trying to run mri_glmfit and while 90% of my files work, some of them display the error below.  I have tried demeaning, and then tried multiplying this value by 100, and I still get the same error.  Any feedback would be greatly appreciated.

mris_preproc done
srcsubject = fsaverage
srcval     = rh.mono_EnglishParityRT_age_gender_TIV.volume.00.mgh
srctype    = 
trgsubject = fsaverage
trgval     = rh.mono_EnglishParityRT_age_gender_TIV.volume.00B.mgh
trgtype    = 
srcsurfreg = sphere.reg
trgsurfreg = sphere.reg
srchemi    = rh
trghemi    = rh
frame      = 0
fwhm-in    = 0
fwhm-out   = 0
label-src  = (null)
label-trg  = (null)
OKToRevFaceOrder  = 1
Reading source surface reg /gpfs/scratch/jtl190/Math_reconstruction/fsaverage/surf/rh.sphere.reg
Loading source data
INFO: trgsubject = srcsubject
Saving target data
Saving to rh.mono_EnglishParityRT_age_gender_TIV.volume.00B.mgh
gdfReadHeader: reading /gpfs/scratch/jtl190/FSGD_files/fsgd_math_mono_EnglishParityRT_age_gender_TIV_demean100.fsgd
INFO: DeMeanFlag keyword not found, DeMeaning will NOT be done.
Continuous Variable Means (all subjects)
0 Age 19.5833 1.32025
1 eTIV 1.61645e+06 145343
2 EnglishParityRT 0.00012207 25139.1
Class Means of each Continuous Variable
1 Monolingual_male  19.7143 1678946.5893 -4197.2796 
2 Monolingual_female  19.4000 1528966.6750 5876.1917 
INFO: gd2mtx_method is dods
Reading source surface /gpfs/scratch/jtl190/Math_reconstruction/fsaverage/surf/rh.white
Number of vertices 163842
Number of faces    327680
Total area         65020.765625
AvgVtxArea       0.396850
AvgVtxDist       0.717994
StdVtxDist       0.193566

$Id: mri_glmfit.c,v 1.196.2.8 2012/11/01 18:51:41 greve Exp $
cwd /gpfs/scratch/jtl190/Math_reconstruction
cmdline mri_glmfit --y rh.mono_EnglishParityRT_age_gender_TIV.volume.00B.mgh --fsgd /gpfs/scratch/jtl190/FSGD_files/fsgd_math_mono_EnglishParityRT_age_gender_TIV_demean100.fsgd --C /gpfs/scratch/jtl190/Contrast_files/Contrast_math_monly_EnglishParityRT_a_g_TIV.txt --surf fsaverage rh --cortex --glmdir rh.mono_EnglishParityRT_age_gender_TIV_100.glmdir 
sysname  Linux
hostname cyberstar129.hpc.rcc.psu.edu
machine  x86_64
user     jtl190
FixVertexAreaFlag = 1
UseMaskWithSmoothing     1
OneSampleGroupMean 0
y    /gpfs/scratch/jtl190/Math_reconstruction/rh.mono_EnglishParityRT_age_gender_TIV.volume.00B.mgh
logyflag 0
usedti  0
FSGD /gpfs/scratch/jtl190/FSGD_files/fsgd_math_mono_EnglishParityRT_age_gender_TIV_demean100.fsgd
labelmask  /gpfs/scratch/jtl190/Math_reconstruction/fsaverage/label/rh.cortex.label
maskinv 0
glmdir rh.mono_EnglishParityRT_age_gender_TIV_100.glmdir
IllCondOK 0
ReScaleX 1
DoFFx 0
Creating output directory rh.mono_EnglishParityRT_age_gender_TIV_100.glmdir
Loading y from /gpfs/scratch/jtl190/Math_reconstruction/rh.mono_EnglishParityRT_age_gender_TIV.volume.00B.mgh
INFO: gd2mtx_method is dods
Saving design matrix to rh.mono_EnglishParityRT_age_gender_TIV_100.glmdir/Xg.dat
Normalized matrix condition is 22568.9
Design matrix ------------------
 1.000   0.000   18.000   0.000   1865790.250   0.000  -8952.208   0.000;
 0.000   1.000   0.000   19.000   0.000   1520429.625   0.000  -4605.208;
 1.000   0.000   19.000   0.000   1749716.750   0.000  -39407.207   0.000;
 0.000   1.000   0.000   18.000   0.000   1589109.250   0.000  -17967.209;
 1.000   0.000   21.000   0.000   1472295.125   0.000   19531.791   0.000;
 1.000   0.000   18.000   0.000   1580381.375   0.000  -17027.209   0.000;
 1.000   0.000   20.000   0.000   1813373.500   0.000   16152.792   0.000;
 1.000   0.000   21.000   0.000   1638616.500   0.000  -9074.208   0.000;
 0.000   1.000   0.000   21.000   0.000   1297920.500   0.000   61860.793;
 0.000   1.000   0.000   18.000   0.000   1634762.625   0.000  -22671.209;
 0.000   1.000   0.000   21.000   0.000   1602611.375   0.000   12763.792;
 1.000   0.000   21.000   0.000   1632452.625   0.000   9395.292   0.000;
--------------------------------
ERROR: matrix is ill-conditioned or badly scaled, condno = 22568.9
--------------------------------
Possible problem with experimental design:
Check for duplicate entries and/or lack of range of
continuous variables within a class.
If you seek help with this problem, make sure to send:
  1. Your command line:
    mri_glmfit --y rh.mono_EnglishParityRT_age_gender_TIV.volume.00B.mgh --fsgd /gpfs/scratch/jtl190/FSGD_files/fsgd_math_mono_EnglishParityRT_age_gender_TIV_demean100.fsgd --C /gpfs/scratch/jtl190/Contrast_files/Contrast_math_monly_EnglishParityRT_a_g_TIV.txt --surf fsaverage rh --cortex --glmdir rh.mono_EnglishParityRT_age_gender_TIV_100.glmdir 
  2. The FSGD file (if using one)
  3. And the design matrix above


I am also attaching the FSGD file.

Best,

Jennifer Legault