Dear Douglas,

Does it also affect the individual data analysis or the volumetric group analysis, e.g. the files in the stats/ folder? So could I use the results of these surface group analyses after running the "-qcache" on V5.3 then?

Thanks,
Kaiming


On 15 March 2016 at 18:00, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:

this only has to do with the qcache part of recon-all, so you could use version 5.3 recon-all -qcache and it should be fine. However, it is not a good idea to try to publish using the analysis from the version of FS that you used. That was a beta version of version 6 and things will change.


On 03/15/2016 01:56 PM, Kaiming Yin wrote:
Dear Douglas,

Is there anything I can do now to fix this now? I don't want to re-run all the data again.

Thanks,
Kaiming


On 15 March 2016 at 16:53, Douglas N Greve <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>> wrote:


    OK, this is a bug that I found and fixed in early Nov. Sorry,
    that's part of the danger of using a beta version.

    On 03/14/2016 12:22 PM, Kaiming Yin wrote:

        Dear Douglas,

        I re-run the "-qcache" on one data and it took 8 mins to
        finish. Still the files are the same, all in 668.6kB size.


        Kaiming

        On 14 March 2016 at 15:56, Douglas Greve
        <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
        <mailto:greve@nmr.mgh.harvard.edu
        <mailto:greve@nmr.mgh.harvard.edu>>> wrote:

            I don't know what happened. I cannot replicate it here.
        Can you
            re-run the recon-all -s -qcache command and verify that
        the files
            are still the same?


            On 3/14/16 11:11 AM, Kaiming Yin wrote:

                Dear Douglas,

                Yes, both of the two pairs of files are the same. i.e.

                mri_diff rh.ad_hv.thick.10.mgh rh.ad_hv.area.10.mgh

                diffcount 0


                mri_diff rh.thickness.fwhm10.fsaverage.mgh
                rh.area.fwhm10.fsaverage.mgh

                diffcount 0


                Does this mean I run the "-qcache" wrongly? I just run
            "recon-all
                -s XX -qcache" on each subject.

                Thanks,
                Kaiming


                On 14 March 2016 at 14:58, Douglas Greve
                <greve@nmr.mgh.harvard.edu
            <mailto:greve@nmr.mgh.harvard.edu>
            <mailto:greve@nmr.mgh.harvard.edu

            <mailto:greve@nmr.mgh.harvard.edu>>> wrote:

                    Check whether rh.ad_hv.thick.10.mgh and
            rh.ad_hv.area.10.mgh
                    are the same, ie,
                    mri_diff  rh.ad_hv.thick.10.mgh rh.ad_hv.area.10.mgh

                    If those are the same, then check whether
                    thickness.fwhm10.fsaverage and
            area.fwhm10.fsaverage  are the
                    same in each subject


                    On 3/14/16 10:53 AM, Kaiming Yin wrote:

                        Dear Douglas,

                        My command lines were, e.g. right thickness
                and right white
                        surface (using the same ad_hv.fsgd and
                group_diff.mtx files
                        in the command lines):


                        ad_hv.fsgd

                        GroupDescriptorFile 1
                        Title AD_HV_GroupAnalysis
                        Class AD
                        Class HV
                        InputAD_003AD
                        InputAD_005AD
                        ...
                        InputHV_ABHV
                        InputHV_AEHV


                        group_diff.mtx

                        1 -1


                        right thickness

                        mris_preproc --fsgd ad_hv.fsgd --cache-in
                        thickness.fwhm10.fsaverage --target fsaverage
                --hemi rh
                        --out rh.ad_hv.thick.10.mgh

                        mri_glmfit --y rh.ad_hv.thick.10.mgh --fsgd
                ad_hv.fsgd dods
                        --C group_diff.mtx --surf fsaverage rh
                --cortex --glmdir
                        rh.ad_hv.thick.glmdir

                        mri_glmfit-sim --glmdir rh.ad_hv.thick.glmdir
                --cache 4 neg
                        --cwp 0.05 --2spaces


                        right white surface

                        mris_preproc --fsgd ad_hv.fsgd --cache-in
                        area.fwhm10.fsaverage --target fsaverage
                --hemi rh --out
                        rh.ad_hv.area.10.mgh

                        mri_glmfit --y rh.ad_hv.area.10.mgh --fsgd
                ad_hv.fsgd dods
                        --C group_diff.mtx --surf fsaverage rh
                --cortex --glmdir
                        rh.ad_hv.area.glmdir

                        mri_glmfit-sim --glmdir rh.ad_hv.area.glmdir
                --cache 4 neg
                        --cwp 0.05 --2spaces


                        Their results were all the same.

                        Thanks,
                        Kaiming


                        ---------- Forwarded message ----------
                        From: Douglas N Greve
                <greve@nmr.mgh.harvard.edu
                <mailto:greve@nmr.mgh.harvard.edu>
                        <mailto:greve@nmr.mgh.harvard.edu
                <mailto:greve@nmr.mgh.harvard.edu>>>
                        To: freesurfer@nmr.mgh.harvard.edu
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                        <mailto:freesurfer@nmr.mgh.harvard.edu
                <mailto:freesurfer@nmr.mgh.harvard.edu>>
                        Cc:
                        Date: Mon, 7 Mar 2016 18:47:11 -0500
                        Subject: Re: [Freesurfer] group analysis all
                measures same
                        results
                        what are your command lines?


                        On 5 March 2016 at 02:01, Kaiming Yin
                        <yinkaiming6987@gmail.com
                <mailto:yinkaiming6987@gmail.com>
                <mailto:yinkaiming6987@gmail.com

                <mailto:yinkaiming6987@gmail.com>>>

                        wrote:

                            Dear guys,

                            I was doing group analysis (command-line)
                on two groups
                            (patients and control, no age or other
                information). The
                            data has been "qcached", and after
                following the three
                            steps as "mris_preproc, mri_glmfit and
                mri_glmfit-sim"
                            shown in the tutorial on the Freesurfer
                website, I
                            obtained the difference on thickness in
                both left and
                            right hemispheres, which seems great.
                However, when I
                            repeated the above steps on other
                measures, e.g. area,
                            area.pial, volume (also replaced the parts of
                            "thickness" in the command lines), the
                results seemed to
                            be exactly the same again as those in the
                thickness
                            comparison, even the p-value numbers in
                the file
                            "cache.th40.neg.sig.cluster.summary" were
                the same. I
                            was using Freesurfer v6.0-beta, and I
                performed the
                            individual data analysis on a linux
                cluster and I
                            copied/downloaded the whole "qcached"
                subject directory
                            to my linux laptop to perform the group
                comparison, both
                            using the same version of Freesurfer, does
                it matter? Or
                            do you know why it happened like this?

                            Thanks,
                            Kaiming



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    --     Douglas N. Greve, Ph.D.
    MGH-NMR Center
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