Hello Doug,<br><br>Thanks for your kind response. I have tried to use mri_glmfit-sim to correct the results. However, no significant differences were observed. To compare with other studies, I would like to report the results (p &lt; 0.001, uncorrected) and mention that they will disappear if corrected by cluster-based threshold method. Is it a acceptable way?<br>
<br>Liang<br><br><div class="gmail_quote">2010/7/11 Douglas N Greve <span dir="ltr">&lt;<a href="mailto:greve@nmr.mgh.harvard.edu">greve@nmr.mgh.harvard.edu</a>&gt;</span><br><blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;">
You should correct for multiple comparisons using cluster-wise correction. See the tutorials on group analysis on our wiki.<br>
<br>
doug<br>
<br>
liang wang wrote:<br>
<blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;"><div><div></div><div class="h5">
Hi,<br>
<br>
Using mri_glmfit, I found significant between-group difference in cortical thickness in some regions. However, there are a lot regions with very small vertices surviving the given threshold. What I need to do is displaying large clusters (e.g. having 20 vertices at least) assumed as &quot;true&quot; difference. I don&#39;t know how to make it by a selected threshold of cluster size . Any suggestions would be appreciated.<br>

<br>
Liang<br>
<br>
-- <br>
Liang Wang, PhD<br>
Postdoctoral Fellow<br>
Woodward Lab<br>
Department of Psychiatry<br>
University of British Columbia<br>
BC Mental Health &amp; Addiction Services<br>
938 West 28th Avenue<br>
Vancouver BC V5Z 4H4<br>
Telephone: 1-604-875-2000 (ext. 4735)<br>
Fax: 1-604-875-3871<br></div></div>
Email: <a href="mailto:wanglbit@gmail.com" target="_blank">wanglbit@gmail.com</a> &lt;mailto:<a href="mailto:wanglbit@gmail.com" target="_blank">wanglbit@gmail.com</a>&gt;<br>
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-- <br>
Douglas N. Greve, Ph.D.<br>
MGH-NMR Center<br>
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</blockquote></div><br><br clear="all"><br>-- <br>Liang Wang, PhD<br>Postdoctoral Fellow<br>Woodward Lab<br>Department of Psychiatry<br>University of British Columbia<br>BC Mental Health &amp; Addiction Services<br>938 West 28th Avenue<br>
Vancouver BC V5Z 4H4<br>Telephone: 1-604-875-2000 (ext. 4735)<br>Fax: 1-604-875-3871<br>Email: <a href="mailto:wanglbit@gmail.com">wanglbit@gmail.com</a><br>