We want to study whether or not presence of periventricular heterotopias affect the thickness, volume, or surface area of the nearest cortical ROI. Since the condition we are studying is caused by failure of neurons to migrate to the cortex, we hypothesized that the nearest cortical ROI would be thinner/smaller compared to those without the heterotopia.

Ryan Michael Nillo
Staff Research Associate I
University of California San Francisco
Department of Radiology and Biomedical Imaging

On May 15, 2019, at 3:10 PM, Bruce Fischl <fischl@nmr.mgh.harvard.edu> wrote:

Hi Ryan

I don't think projection of that kind of ROI is well-posed. Different parts of it are probably closest to wildly different parts of cortex. What are you trying to acheive?

cheers
Bruce

On Wed, 15 May 2019, Nillo, Ryan Michael R wrote:

External Email - Use Caution
Hello FreeSurfer users/developers,
I have a subcortical ROI that I want to project to the nearest cortical vertex (see screenshot). So
far, I have used the command mri_vol2surf --mov subject/mri/lh.het.nii --reg
subject/mri/transforms/talairach.lta --hemi lh —o subject/surf/lh.het.mgh to project these voxels to
the nearest vertex on the cortex. I am not sure if this is the correct way to do this because using
mris_anatomical_stats on the result does not produce any thickness file. Any help would be greatly
appreciated.
[IMAGE]
Ryan Michael Nillo
Staff Research Associate I
University of California San Francisco
Department of Radiology and Biomedical Imaging

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