Hi all,

I have seen others post a similar problem on the freesurfer mailing list but I could not find a solution.

When I edit a volume using control points, I am noticing that the use of CP edits adversely effects the wm/gm surfaces in the resulting re-processed image. Like others have reported, the surfaces are adversely affected in locations distant from the CP edits. The temporal lobes are particularly affected.

We are using freesurfer 5.1.
I have noticed the following things:

1. The problem occurs irrespective of the number of control points added, i.e. whether >100 or <10 control points added
2. The problem occurred when only one CP was added in a voxel that was clearly wm
3. The problem did not occur after reprocessing with FS 4.5
4. I have tried the flag to disable mri_ca_normalize when reprocessing with –autorecon2. This did not seem to help. I used the command: recon-all –nocanorm –autorecon2-cp –subjid $SUBJ
   

I have screenshots available that illustrate the changes in the surfaces after reprocessing.

Could anyone help with this problem?

Thank-you,

Vanessa