Hello doug,

while running the mir_glmfit problem, i encountered this problem “

INFO: DeMeanFlag keyword not found, DeMeaning will NOT be done.

Continuous Variable Means (all subjects)

0 Age 39.9375 17.3312

1 Education 15.5625 1.99902

2 Firstscore 1.03375 0.341785

3 Secondscore 1.03906 0.370678

4 Thirdscore 1.13844 0.4768

5 Averagescore 1.07375 0.364046

Class Means of each Continuous Variable

1 Group1  35.6316  15.0526   1.0342   1.2111   1.4289   1.2305

2 Group2  46.2308  16.3077   1.0331   0.7877   0.7138   0.8446

INFO: gd2mtx_method is dods

Reading source surface /Users/paul/Desktop/improvervsdeclinermri/fsaverage/surf/lh.white

Number of vertices 163842

Number of faces    327680

Total area         65416.648438

AvgVtxArea       0.399267

AvgVtxDist       0.721953

StdVtxDist       0.195470

 

$Id: mri_glmfit.c,v 1.196.2.6 2011/05/05 20:54:25 greve Exp $

cwd /Users/paul/Desktop/improvervsdeclinermri

cmdline mri_glmfit --y lh.new.MOT.thickness.10B.mgh --fsgd new.MOT.fsgd dods --C new.firstmatrix.mtx --C new.secondmatrix.mtx --C new.thirdmatrix.mtx --C new.fourthmatrix.mtx --C new.fifthmatrix.mtx --C new.sixthmatrix.mtx --C new.seventhmatrix.mtx --C new.eightmatrix.mtx --C new.ninethmatrix.mtx --C new.tenthmatrix.mtx --surf fsaverage lh --cortex --glmdir lh.new.MOT.glmdir

sysname  Darwin

hostname TC-CT-LAB4-iMAC.local

machine  x86_64

user     paul

FixVertexAreaFlag = 1

UseMaskWithSmoothing     1

OneSampleGroupMean 0

y    /Users/paul/Desktop/improvervsdeclinermri/lh.new.MOT.thickness.10B.mgh

logyflag 0

usedti  0

FSGD new.MOT.fsgd

labelmask  /Users/paul/Desktop/improvervsdeclinermri/fsaverage/label/lh.cortex.label

maskinv 0

glmdir lh.new.MOT.glmdir

IllCondOK 0

ReScaleX 1

DoFFx 0

Creating output directory lh.new.MOT.glmdir

Loading y from /Users/paul/Desktop/improvervsdeclinermri/lh.new.MOT.thickness.10B.mgh

INFO: gd2mtx_method is dods

Saving design matrix to lh.new.MOT.glmdir/Xg.dat

Normalized matrix condition is 1.27568e+06

Design matrix ------------------

 

1.000   0.000   23.000   0.000   15.000   0.000   1.680   0.000   1.780   0.000   2.110   0.000   1.860   0.000;

 1.000   0.000   43.000   0.000   16.000   0.000   0.840   0.000   0.890   0.000   1.190   0.000   0.970   0.000;

 1.000   0.000   39.000   0.000   17.000   0.000   0.790   0.000   0.840   0.000   1.220   0.000   0.950   0.000;

 1.000   0.000   19.000   0.000   13.000   0.000   0.840   0.000   1.060   0.000   1.260   0.000   1.050   0.000;

 1.000   0.000   28.000   0.000   13.000   0.000   1.060   0.000   1.120   0.000   1.370   0.000   1.180   0.000

 …………………………………………………………………………………………………………………...

ERROR: matrix is ill-conditioned or badly scaled, condno = 1.27568e+06

--------------------------------

Possible problem with experimental design:

Check for duplicate entries and/or lack of range of

continuous variables within a class.

If you seek help with this problem, make sure to send:

  1. Your command line:

    mri_glmfit --y lh.new.MOT.thickness.10B.mgh --fsgd new.MOT.fsgd dods --C new.firstmatrix.mtx —C new.secondmatrix.mtx --C new.thirdmatrix.mtx --C new.fourthmatrix.mtx --C new.fifthmatrix.mtx --C new.sixthmatrix.mtx --C new.seventhmatrix.mtx --C new.eightmatrix.mtx --C new.ninethmatrix.mtx --C new.tenthmatrix.mtx --surf fsaverage lh --cortex --glmdir lh.new.MOT.glmdir

  2. The FSGD file (if using one)

  3. And the design matrix above”

Below are my fsgd file and contrast matrix. I can’t add DeMeanFlag 1 because I am using dods and interested in group difference. Also, none of the responses from people with similar error helped me. I am using version 5.1

Thank you very much. 

Paul



GroupDescriptorFile 1

Title MOT

Class Group1

Class Group2

Variables                       Age     Education       Firstscore      Secondscore     Thirdscore      Averagescore

Input 01053p/fsdir Group1       23      15              1.68            1.78            2.11            1.86

Input 01054p/fsdir Group1       43      16              0.84            0.89            1.19            0.97

Input 01061p/fsdir Group1       39      17              0.79            0.84            1.22            0.95

Input 01062p/fsdir Group1       19      13              0.84            1.06            1.26            1.05

Input 01074p/fsdir Group1       28      13              1.06            1.12            1.37            1.18

Input 01080p/fsdir Group1       28      18              0.97            1.26            1.33            1.19

Input 01099p/fsdir Group1       37      16              0.87            1.15            1.37            1.13

Input 01101p/fsdir Group1       20      14              1.00            1.37            1.45            1.27

Input 01102p/fsdir Group1       58      16              0.97            1.12            1.41            1.27

Input 01121p/fsdir Group1       28      18              0.87            1.00            1.00            0.96

Input 01127p/fsdir Group1       46      16              0.77            1.06            1.58            1.14

Input 01128p/fsdir Group1       21      16              1.58            1.78            1.78            1.71

Input 01130p/fsdir Group1       22      16              1.50            1.22            1.63            1.45

Input 01131p/fsdir Group1       19      13              1.54            1.68            2.11            1.78

Input 01141p/fsdir Group1       17      12              1.00            1.09            1.30            1.13

Input 1044pp/fsdir Group1       51      16              0.94            1.54            1.68            1.39

Input 1053pp/fsdir Group1       44      16              1.22            1.30            1.50            1.34

Input 1058pp/fsdir Group1       78      12              0.61            1.12            1.15            0.96

Input 1060pp/fsdir Group1       56      13              0.60            0.63            0.71            0.65

Input 01047p/fsdir Group2       50      18              1.12            0.94            0.94            1.00

Input 01075p/fsdir Group2       20      15              1.12            0.84            0.60            0.85

Input 01077p/fsdir Group2       48      16              0.43            0.35            0.35            0.38

Input 01091p/fsdir Group2       23      16              1.58            1.22            1.22            1.34

Input 01096p/fsdir Group2       17      17              1.50            1.26            1.19            1.32

Input 01113p/fsdir Group2       51      18              0.75            0.69            0.60            0.68

Input 01124p/fsdir Group2       43      18              1.33            0.89            0.87            1.03

Input 01134p/fsdir Group2       59      16              0.82            0.60            0.60            0.67

Input 1004pp/fsdir Group2       46      19              0.82            0.79            0.71            0.77

Input 1040pp/fsdir Group2       64      13              0.92            0.55            0.46            0.64

Input 1043pp/fsdir Group2       49      16              1.58            1.03            0.89            1.17

Input 1064pp/fsdir Group2       78      12              0.40            0.11            0.10            0.20

Input 1067pp/fsdir Group2       53      18              1.06            0.97            0.75            0.93


first contrast matrix

1 -1 0 0 0 0 0 0 0 0 0 0 0 0

group1 greater than group 2 regressing out age, education, first, second, third and average

second constrast matrix

-1 1 0 0 0 0 0 0 0 0 0 0 0 0

group 2 greater than group 1 regressing out age, education, first, second, third and average

third contrast matrix

0 0 0 0 0 0 0.5 -0.5 0 0 0 0 0 0

group 1 showing increasing correlation with first score compared to group 2 

fourth contrast matrix

0 0 0 0 0 0 -0.5 0.5 0 0 0 0 0 0

group2 showing showing increasing correlation with first score compared to group 1

fifth contrast matrix

0 0 0 0 0 0 0 0 0.5 -0.5 0 0 0 0

group1 showing showing increasing correlation with second score compared to group 2

sixth contrast matrix

0 0 0 0 0 0 0 0 -0.5 0.5 0 0 0 0

group2 showing showing increasing correlation with second score compared to group 1

seventh contrast matrix 

0 0 0 0 0 0 0 0 0 0 0.5 -0.5 0 0

group1 showing showing increasing correlation with third score compared to group 2

eighth contrast matrix

0 0 0 0 0 0 0 0 0 0 -0.5 0.5 0 0

group2 showing showing increasing correlation with third score compared to group 1

ninety contrast matrix 

0 0 0 0 0 0 0 0 0 0 0 0 0.5 -0.5

group1 showing showing increasing correlation with average score compared to group 2

tenth contrast matrix

0 0 0 0 0 0 0 0 0 0 0 0 -0.5 0.5

group2 showing showing increasing correlation with average score compared to group 1