Freesurfer experts,


I have a few fractional anisotropy images linearly registered to an FA atlas. I'd like to run FNIRT on them with reference the FA Atlas, but when I do, the output is entirely NaNs. 


I ran the program in verbose mode--and everything is NaN's. e.g.:


 

SSD = -nan    n = 0    Disp reg = nan    Int reg = -nan    Total Cost = nan
Jacobian range is nan -- nan
***Going to next resolution level***
Setting subsampling
Setting reg mode
Setting lambda
New Lambda: 30
SSD = -nan    n = 0    Disp reg = nan    Int reg = -nan    Total Cost = nan
SSD = -nan    n = 0    Disp reg = nan    Int reg = -nan    Total Cost = nan
SSD = -nan    n = 0    Disp reg = nan    Int reg = -nan    Total Cost = nan
SSD = -nan    n = 0    Disp reg = nan    Int reg = -nan    Total Cost = nan


Is this simply because there are NaN's in the input image? Will replacing them with 0 fix the issue, or will it lead to strange behaviour in FNIRT?


Any help is appreciated.


Quentin Funk, PhD
Houston Methodist Research Institute
713-363-9003

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