Hi Malav,

Freesurfer is guided by an atlas that was built from human adult brain images. In the past though, we did have collaborators who have tried some modified versons of the pipeline to work on non-human data. Here are some pointers:

https://surfer.nmr.mgh.harvard.edu/fswiki/MonkeyData
https://hal.archives-ouvertes.fr/hal-01854607/document

As far as I know elephant brain images have not yet been processed. Good luck, Lilla


From: freesurfer-bounces@nmr.mgh.harvard.edu <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Malav Shah <malav.shah@bccn-berlin.de>
Sent: Wednesday, April 6, 2022 1:10 PM
To: freesurfer@nmr.mgh.harvard.edu <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] recontruction of an elephant brain
 

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hi,
I am trying to reconstruct elephant brain MRI. I am wondering if FreeSurfer can manage this, or does the recon-all command has an inherent bias for human data.
Does anyone have an experience using FreeSurfer with a non-human mammal for such purposes?

I have some hopes with this idea, because I am not trying to achieve parcellation or segmentation. Rather, we want to separate White matter from grey Matter, and then probe into various surface measurements across cortical regions. So as per my understanding, all I am expecting from FreeSurfer, is WM-GM segregation, and later (if possible) cortical surface flattening, and DTI.

All words of advice are welcome.
Thanks :)

Malav Shah
PhD candidate, Michael Brecht Lab,
Humboldt University zu Berlin.
(+49) 163-216-9391