Hi Cris,

in your case, fsaverage may not be optimal, but often it does it's job even if ages are far away.

Still I would recommend c) or you can also select a specific subject from your data as the template and exclude it from the analysis.

For c) you'd have to build the template, but I have never done that. Probably the wiki is right.

Best, Martin

Hi Doug, Martin, et al.,

I am going to use the LME tools for a study in kids 8-15 y.o. (some with brain injury). RE the target space (mris_preproc and mri_surf2surf), the LME wiki page says "study_average". I am unclear if this should be

a) average of all subjects at TP 1 (or final, or mid)

b) average of all subjects and all TP's

c) average of all within-subject templates (created from recon-all -base)

d) fsaverage

I suspect (d) is wrong for this study and (c) is right, but want to double-check. In that case, would I then follow the steps on the wiki page for creating a template?

Thanks,

Chris

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