Hello,

I have been successfully running FreeSurfer 4.5 on my MacOSX 10.5.8 with no issues. I recently installed FreeSurfer 5.1 to a separate directory on the same laptop to analyze a new dataset but I am now having various issues using FreeSurfer version 4.5.

For Version 4.5, I path the freesurfer directories as follows (identical to before installing version 5.1):

setenv FREESURFER_HOME /Applications/freesurfer

setenv SUBJECTS_DIR /MRIData/Root/freesurfer/TRDsubjects_dir

source $FREESURFER_HOME/SetUpFreeSurfer.csh

--------- freesurfer-Darwin-leopard-i686-stable-pub-v4.5.0 --------

Setting up environment for FreeSurfer/FS-FAST (and FSL)

FREESURFER_HOME /Applications/freesurfer

FSFAST_HOME /Applications/freesurfer/fsfast

FSF_OUTPUT_FORMAT nii

SUBJECTS_DIR /MRIData/Root/freesurfer/TRDsubjects_dir

MNI_DIR /Applications/freesurfer/mni

The issue is that now various commands no longer function in version 4.5.

For example when typing tkmedit, tksurfer or qdec, I get the following type of error:

tkmedit.bin: Command not found.

Is it possible that although I installed version 5.1 in a separate directory, that some files were deleted or moved in version 4.5? Is my 4.5 license no longer valid now that I have installed version 5.1 with a new license? It is confusing since some commands appear to function, such as mri_convert and recon-all, but anything involving a GUI seems not to function.

Any help would be appreciated.

thanks,

Jennifer