Can you say more about your approach? Are you subtracting the two time points explicitly and computing a paired t? Or are you using the repeated measures anova approach. Send the FSGD file

On 11/30/2021 11:04 AM, PDMD SRALab wrote:

        External Email - Use Caution        

We are using a paired analysis approach to study cortical thickness in a dataset with 2 timepoints (called pre-protocol and post-protocol). Regarding the mean cluster summary (contrast: [1 0]), we understand positive values to mean pre > post (thinning) and negative values to mean post > pre (thickening). The covariate results are more difficult to interpret. For instance, we’re interested in looking at the effects of age (contrast: [0 1]) on the cortical thickness results. In the age cluster summary, is it fair to interpret positive results as positive correlation (older subjects show more thickening) and negative results as inverse correlation (older subjects show more thinning) or is the interpretation more complex than this? We’re getting mainly negative cluster results for age so this interpretation may make sense, but we’d like more clarity. Thank you for your help.

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be http://www.massgeneralbrigham.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Please note that this e-mail is not secure (encrypted).  If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately.  Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.