Hello, Freesurfer experts:

We are extracting the average cortical thickness of each hemisphere for every subject using mris_anatomical_stats. We found that for one subject (attached below), the thickness measures are quite similar but the ¡°intrinsic curvature index¡± differs drastically between left/right hemispheres. Will this curvature index affect the validity of our thickness measure?

Thanks in advance

Karl

***the left hemisphere
mris_anatomical_stats -l lh.cortex.label -f subject1l.txt subject1 lh
limiting computations to label lh.cortex.label.
reading volume /usr/local/freesurfer/subjects/subject1/mri/wm.mgz...
reading input surface /usr/local/freesurfer/subjects/subject1/surf/lh.white...
reading input pial surface /usr/local/freesurfer/subjects/subject1/surf/lh.pial...
reading input white surface /usr/local/freesurfer/subjects/subject1/surf/lh.white...
structure is "lh.cortex.label"
number of vertices                      = 157421
total surface area                      = 102165 mm^2
total gray matter volume                = 290073 mm^3
average cortical thickness              = 2.488 mm +- 0.694 mm
average integrated rectified mean curvature     = 0.170
average integrated rectified Gaussian curvature = 0.105
folding index                           = 4980
intrinsic curvature index               = 592.3