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Maybe you could let us know the details about what version of MacOS you are running,  how much memory your machine has and what the M1 processor has for efficiency and performance cores.

- R.

On Jun 8, 2025, at 21:25, Treeby, Bradley <b.treeby@ucl.ac.uk> wrote:

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Dear FreeSurfer Developers and Community,

I am trying to run Bayesian Segmentation with the Histological Atlas "NextBrain" in FreeSurfer on an M1 Mac on the CPU. I downloaded the 8.0.0 installer and followed the instructions, downloaded the atlas, etc.

If I run mri_histo_atlas_segment_fast. It runs until “Reading in atlas” and then fails with a long error trace including "An attempt has been made to start a new process before the current process has finished its bootstrapping phase."

If I run mri_histo_atlas_segment_fireants it quits almost immediately, complaining about missing modules (‘fireants.registration.deformation.geodesic’).

My call in both cases follows:

mri_histo_atlas_segment_xxx $SUBJECT_IM $SUBJECTS_DIR/$SUBJECT_ID/mri_histo_atlas_seg/ 0 $FS_THREADS

Are there any pointers, or some setup steps that I’ve missed? If it’s helpful, other tools like recon-all are working correctly. I’m excited to try this out!

Best,

Bradley Treeby.
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