7.3.2 --mov: Using 5771302/5771302_y0_t1_n3_lesion_mask_leap-filled.nii.gz as movable/source volume. --mov: Using 5771302/5771302_y1_t1_n3_lesion_mask_leap-filled.nii.gz as movable/source volume. --mov: Using 5771302/5771302_y2_t1_n3_lesion_mask_leap-filled.nii.gz as movable/source volume. Total: 3 input volumes --template: Using 5771302/mean.mgz as template output volume. --satit: Will estimate SAT iteratively! --mapmov: Will save mapped movables/sources! reading source '5771302/5771302_y0_t1_n3_lesion_mask_leap-filled.nii.gz'... converting source '5771302/5771302_y0_t1_n3_lesion_mask_leap-filled.nii.gz' to bspline ... MRItoBSpline degree 3 reading source '5771302/5771302_y1_t1_n3_lesion_mask_leap-filled.nii.gz'... converting source '5771302/5771302_y1_t1_n3_lesion_mask_leap-filled.nii.gz' to bspline ... MRItoBSpline degree 3 reading source '5771302/5771302_y2_t1_n3_lesion_mask_leap-filled.nii.gz'... converting source '5771302/5771302_y2_t1_n3_lesion_mask_leap-filled.nii.gz' to bspline ... MRItoBSpline degree 3 Will use TP 1 as random initial target (seed 401689 ). MultiRegistration::initializing Xforms (init 1 , maxres 0 , iterate 5 , epsit 0.01 ) : [init] ========================= TP 2 to TP 1 ============================== Register TP 2 ( 5771302/5771302_y1_t1_n3_lesion_mask_leap-filled.nii.gz ) to TP 1 ( 5771302/5771302_y0_t1_n3_lesion_mask_leap-filled.nii.gz ) [init] ========================= TP 3 to TP 1 ============================== Register TP 3 ( 5771302/5771302_y2_t1_n3_lesion_mask_leap-filled.nii.gz ) to TP 1 ( 5771302/5771302_y0_t1_n3_lesion_mask_leap-filled.nii.gz ) -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using cubic bspline cubic bspline MRItoBSpline degree 3 MRItoBSpline degree 3 -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using cubic bspline MRItoBSpline degree 3 -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using cubic bspline MRItoBSpline degree 3 - Max Resolution used: 2 -- gpS ( 47 , 64 , 64 ) -- gpT ( 47 , 64 , 64 ) - running loop to estimate saturation parameter: - Max Resolution used: 2 -- gpS ( 47 , 64 , 64 ) -- gpT ( 47 , 64 , 64 ) - running loop to estimate saturation parameter: Adjusting final transform due to initial resampling (voxel or size changes) ... Adjusting final transform due to initial resampling (voxel or size changes) ... Adjusting final transform due to initial resampling (voxel or size changes) ... Adjusting final transform due to initial resampling (voxel or size changes) ... Input rotation's max deviation from rotation is: 1.47514e-07 computing mean coord of TP 1 ( 5771302/5771302_y0_t1_n3_lesion_mask_leap-filled.nii.gz ) mapping back to rot, err = 2.71948e-16 computing mean coord of TP 2 ( 5771302/5771302_y1_t1_n3_lesion_mask_leap-filled.nii.gz ) mapping back to rot, err = 7.3757e-08 computing mean coord of TP 3 ( 5771302/5771302_y2_t1_n3_lesion_mask_leap-filled.nii.gz ) mapping back to rot, err = 7.3757e-08 Computing first template mapping movs and creating initial template... using median -- Template : (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. ======================================================= Working on global iteration : 1 ======================================================= noxformits = 3 Working on TP 2 Working on TP 1 Working on TP 3 -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using cubic bspline -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using cubic bspline -- Original : (1, 0.9375, 0.9375)mm and (176, 256, 256) voxels. -- Resampled: (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. -- Reslicing using cubic bspline MRItoBSpline degree 3 MRItoBSpline degree 3 MRItoBSpline degree 3 - Max Resolution used: 2 -- gpS ( 47 , 64 , 64 ) -- gpT ( 47 , 64 , 64 ) - running loop to estimate saturation parameter: - Max Resolution used: 2 -- gpS ( 47 , 64 , 64 ) -- gpT ( 47 , 64 , 64 ) - running loop to estimate saturation parameter: - Max Resolution used: 2 -- gpS ( 47 , 64 , 64 ) -- gpT ( 47 , 64 , 64 ) - running loop to estimate saturation parameter: - running multi-resolutional registration on TP 3... Adjusting final transform due to initial resampling (voxel or size changes) ... - running multi-resolutional registration on TP 1... Adjusting final transform due to initial resampling (voxel or size changes) ... - running multi-resolutional registration on TP 2... Adjusting final transform due to initial resampling (voxel or size changes) ... tp 3 distance: 0.0216354 tp 1 distance: 0.0147146 - mapping tp 1 to template (cubic bspline) ... - mapping tp 3 to template (cubic bspline) ... tp 2 distance: 0.0296246 - mapping tp 2 to template (cubic bspline) ... Finished TP : 2 ===================================================== Finished TP : 1 ===================================================== Finished TP : 3 ===================================================== Global Iteration 1 Distances: 0.0147146 0.0296246 0.0216354 Maxchange: 0.0296246 Computing new template 1 using median -- Template : (0.9375, 0.9375, 0.9375)mm and (188, 256, 256) voxels. DONE : computeTemplate Writing final template: 5771302/mean.mgz Writing final transforms (warps etc.)... registration took 3 minutes and 18 seconds. Thank you for using RobustTemplate! If you find it useful and use it for a publication, please cite: Within-Subject Template Estimation for Unbiased Longitudinal Image Analysis M. Reuter, N.J. Schmansky, H.D. Rosas, B. Fischl. NeuroImage 2012. http://dx.doi.org/10.1016/j.neuroimage.2012.02.084 http://reuter.mit.edu/papers/reuter-long12.pdf Constructing image-to-world transform from header information (5771302/5771302_tp0_t1_reg.mgz) Read image: 5771302/5771302_tp0_t1_reg.mgz Constructing image-to-world transform from header information (5771302/5771302_tp1_t1_reg.mgz) Read image: 5771302/5771302_tp1_t1_reg.mgz Constructing image-to-world transform from header information (5771302/5771302_tp2_t1_reg.mgz) Read image: 5771302/5771302_tp2_t1_reg.mgz Wrote image and transform to file ../results_samseg_long/5771302/base/mode01_average.mgz Constructing image-to-world transform from header information (../results_samseg_long/5771302/base/mode01_average.mgz) Read image: ../results_samseg_long/5771302/base/mode01_average.mgz Constructing image-to-world transform from header information (/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/template.nii) Read image: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/template.nii Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE min: 0 max: 8664.97 robustMin: 0 robustMax: 6301.01 histogram[ 0 ]: 58952 histogram[ 1 ]: 41843 histogram[ 2 ]: 21043 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.126521 cumulativeHistogram[ 1 ]: 0.216322 cumulativeHistogram[ 2 ]: 0.261484 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 AFFINE min: 0 max: 8664.97 robustMin: 0 robustMax: 6301.01 histogram[ 0 ]: 58952 histogram[ 1 ]: 41843 histogram[ 2 ]: 21043 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.126521 cumulativeHistogram[ 1 ]: 0.216322 cumulativeHistogram[ 2 ]: 0.261484 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 0 min: 0 max: 8664.97 robustMin: 0 robustMax: 6301.01 histogram[ 0 ]: 58952 histogram[ 1 ]: 41843 histogram[ 2 ]: 21043 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.126521 cumulativeHistogram[ 1 ]: 0.216322 cumulativeHistogram[ 2 ]: 0.261484 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 0 min: 0 max: 8664.97 robustMin: 0 robustMax: 6301.01 histogram[ 0 ]: 58952 histogram[ 1 ]: 41843 histogram[ 2 ]: 21043 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.126521 cumulativeHistogram[ 1 ]: 0.216322 cumulativeHistogram[ 2 ]: 0.261484 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlasForAffineRegistration.txt.gz Transforming points Transforming points AFFINE L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 0 min: 0 max: 8664.97 robustMin: 0 robustMax: 6301.01 histogram[ 0 ]: 58952 histogram[ 1 ]: 41843 histogram[ 2 ]: 21043 histogram[ 3997 ]: 0 histogram[ 3998 ]: 0 histogram[ 3999 ]: 1 cumulativeHistogram[ 0 ]: 0.126521 cumulativeHistogram[ 1 ]: 0.216322 cumulativeHistogram[ 2 ]: 0.261484 cumulativeHistogram[ 3997 ]: 0.999998 cumulativeHistogram[ 3998 ]: 0.999998 cumulativeHistogram[ 3999 ]: 1 Constructing image-to-world transform from header information (../results_samseg_long/5771302/base/mode01_average.mgz) Read image: ../results_samseg_long/5771302/base/mode01_average.mgz Constructing image-to-world transform from header information (5771302/5771302_tp0_t1_reg.mgz) Read image: 5771302/5771302_tp0_t1_reg.mgz Constructing image-to-world transform from header information (5771302/5771302_tp1_t1_reg.mgz) Read image: 5771302/5771302_tp1_t1_reg.mgz Constructing image-to-world transform from header information (5771302/5771302_tp2_t1_reg.mgz) Read image: 5771302/5771302_tp2_t1_reg.mgz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points performing affine atlas registration image: ../results_samseg_long/5771302/base/mode01_average.mgz template: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/template.nii maximalDeformation=1.0000 minLogLikelihood=-0.8220 maximalDeformation=5.1688 minLogLikelihood=-0.8539 maximalDeformation=2.4464 minLogLikelihood=-0.8893 maximalDeformation=0.9654 minLogLikelihood=-0.8955 maximalDeformation=2.4389 minLogLikelihood=-0.9037 maximalDeformation=2.2246 minLogLikelihood=-0.9075 maximalDeformation=1.3765 minLogLikelihood=-0.9106 maximalDeformation=0.4294 minLogLikelihood=-0.9107 maximalDeformation=0.2028 minLogLikelihood=-0.9109 maximalDeformation=0.1479 minLogLikelihood=-0.9109 maximalDeformation=0.2362 minLogLikelihood=-0.9111 maximalDeformation=0.1577 minLogLikelihood=-0.9111 maximalDeformation=0.0265 minLogLikelihood=-0.9112 maximalDeformation=0.3540 minLogLikelihood=-0.9112 maximalDeformation=0.0000 minLogLikelihood=-0.9112 appliedScaling: 1.0111 maximalDeformation=1.0000 minLogLikelihood=-0.9253 maximalDeformation=0.1794 minLogLikelihood=-0.9254 maximalDeformation=0.1618 minLogLikelihood=-0.9255 maximalDeformation=0.1159 minLogLikelihood=-0.9255 maximalDeformation=0.1099 minLogLikelihood=-0.9255 maximalDeformation=0.1604 minLogLikelihood=-0.9255 maximalDeformation=0.0000 minLogLikelihood=-0.9255 appliedScaling: 1.0041 maximalDeformation=1.0000 minLogLikelihood=-0.9283 maximalDeformation=0.3205 minLogLikelihood=-0.9287 maximalDeformation=0.1259 minLogLikelihood=-0.9287 maximalDeformation=0.3077 minLogLikelihood=-0.9289 maximalDeformation=0.2601 minLogLikelihood=-0.9290 maximalDeformation=0.0692 minLogLikelihood=-0.9291 maximalDeformation=0.0000 minLogLikelihood=-0.9291 appliedScaling: 1.0012 writing template transform to ../results_samseg_long/5771302/base/template.lta writing talairach transform to ../results_samseg_long/5771302/base/samseg.talairach.lta ##---------------------------------------------- Samsegment Options ##---------------------------------------------- output directory: ../results_samseg_long/5771302/base input images: ../results_samseg_long/5771302/base/mode01_average.mgz modelSpecifications: {'FreeSurferLabels': [0, 165, 258, 16, 24, 8, 47, 15, 259, 3, 42, 7, 46, 41, 2, 63, 54, 18, 53, 44, 17, 31, 5, 85, 60, 28, 14, 26, 12, 51, 62, 58, 77, 4, 30, 43, 52, 11, 49, 13, 50, 10, 80, 72], 'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'names': ['Unknown', 'Skull', 'Soft_Nonbrain_Tissue', 'Brain-Stem', 'CSF', 'Left-Cerebellum-Cortex', 'Right-Cerebellum-Cortex', '4th-Ventricle', 'Fluid_Inside_Eyes', 'Left-Cerebral-Cortex', 'Right-Cerebral-Cortex', 'Left-Cerebellum-White-Matter', 'Right-Cerebellum-White-Matter', 'Right-Cerebral-White-Matter', 'Left-Cerebral-White-Matter', 'Right-choroid-plexus', 'Right-Amygdala', 'Left-Amygdala', 'Right-Hippocampus', 'Right-Inf-Lat-Vent', 'Left-Hippocampus', 'Left-choroid-plexus', 'Left-Inf-Lat-Vent', 'Optic-Chiasm', 'Right-VentralDC', 'Left-VentralDC', '3rd-Ventricle', 'Left-Accumbens-area', 'Left-Putamen', 'Right-Putamen', 'Right-vessel', 'Right-Accumbens-area', 'WM-hypointensities', 'Left-Lateral-Ventricle', 'Left-vessel', 'Right-Lateral-Ventricle', 'Right-Pallidum', 'Left-Caudate', 'Right-Thalamus', 'Left-Pallidum', 'Right-Caudate', 'Left-Thalamus', 'non-WM-hypointensities', '5th-Ventricle'], 'colors': [[0, 0, 0, 0], [255, 165, 0, 255], [128, 128, 128, 255], [119, 159, 176, 255], [60, 60, 60, 255], [230, 148, 34, 255], [230, 148, 34, 255], [42, 204, 164, 255], [128, 0, 128, 255], [205, 62, 78, 255], [205, 62, 78, 255], [220, 248, 164, 255], [220, 248, 164, 255], [0, 225, 0, 255], [245, 245, 245, 255], [0, 200, 221, 255], [103, 255, 255, 255], [103, 255, 255, 255], [220, 216, 20, 255], [196, 58, 250, 255], [220, 216, 20, 255], [0, 200, 200, 255], [196, 58, 250, 255], [234, 169, 30, 255], [165, 42, 42, 255], [165, 42, 42, 255], [204, 182, 142, 255], [255, 165, 0, 255], [236, 13, 176, 255], [236, 13, 176, 255], [160, 32, 240, 255], [255, 165, 0, 255], [200, 70, 255, 255], [120, 18, 134, 255], [160, 32, 240, 255], [120, 18, 134, 255], [13, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [12, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [164, 108, 226, 255], [120, 190, 150, 255]], 'sharedGMMParameters': [GMMparameter(mergedName='Unknown', numberOfComponents=1, searchStrings=['Unknown', 'Skull']), GMMparameter(mergedName='GlobalWM', numberOfComponents=1, searchStrings=['White', 'Brain-Stem', 'VentralDC', 'Optic-Chiasm', 'Thalamus', 'Pallidum']), GMMparameter(mergedName='GlobalGM', numberOfComponents=1, searchStrings=['Cortex', 'Caudate', 'Hippocampus', 'Amygdala', 'Accumbens', 'hypointensities', 'Thalamus']), GMMparameter(mergedName='GlobalCSF_messy', numberOfComponents=1, searchStrings=['CSF', 'vessel', 'choroid-plexus', 'Fluid']), GMMparameter(mergedName='GlobalCSF_clean', numberOfComponents=1, searchStrings=['Ventricle', 'Inf-Lat-Vent', 'Fluid']), GMMparameter(mergedName='Putamen', numberOfComponents=1, searchStrings=['Putamen']), GMMparameter(mergedName='Soft', numberOfComponents=3, searchStrings=['Soft'])], 'useDiagonalCovarianceMatrices': True, 'maskingProbabilityThreshold': 0.5, 'maskingDistance': 10.0, 'K': 0.1, 'biasFieldSmoothingKernelSize': 50, 'whiteMatterAndCortexSmoothingSigma': 0} optimizationOptions: {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz', 'targetDownsampledVoxelSpacing': 2.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}, {'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} [0.9375 0.9375 0.9375] ##---------------------------------------------- Samsegment Options ##---------------------------------------------- output directory: ../results_samseg_long/5771302 input images: 5771302/5771302_tp0_t1_reg.mgz modelSpecifications: {'FreeSurferLabels': [0, 165, 258, 16, 24, 8, 47, 15, 259, 3, 42, 7, 46, 41, 2, 63, 54, 18, 53, 44, 17, 31, 5, 85, 60, 28, 14, 26, 12, 51, 62, 58, 77, 4, 30, 43, 52, 11, 49, 13, 50, 10, 80, 72], 'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'names': ['Unknown', 'Skull', 'Soft_Nonbrain_Tissue', 'Brain-Stem', 'CSF', 'Left-Cerebellum-Cortex', 'Right-Cerebellum-Cortex', '4th-Ventricle', 'Fluid_Inside_Eyes', 'Left-Cerebral-Cortex', 'Right-Cerebral-Cortex', 'Left-Cerebellum-White-Matter', 'Right-Cerebellum-White-Matter', 'Right-Cerebral-White-Matter', 'Left-Cerebral-White-Matter', 'Right-choroid-plexus', 'Right-Amygdala', 'Left-Amygdala', 'Right-Hippocampus', 'Right-Inf-Lat-Vent', 'Left-Hippocampus', 'Left-choroid-plexus', 'Left-Inf-Lat-Vent', 'Optic-Chiasm', 'Right-VentralDC', 'Left-VentralDC', '3rd-Ventricle', 'Left-Accumbens-area', 'Left-Putamen', 'Right-Putamen', 'Right-vessel', 'Right-Accumbens-area', 'WM-hypointensities', 'Left-Lateral-Ventricle', 'Left-vessel', 'Right-Lateral-Ventricle', 'Right-Pallidum', 'Left-Caudate', 'Right-Thalamus', 'Left-Pallidum', 'Right-Caudate', 'Left-Thalamus', 'non-WM-hypointensities', '5th-Ventricle'], 'colors': [[0, 0, 0, 0], [255, 165, 0, 255], [128, 128, 128, 255], [119, 159, 176, 255], [60, 60, 60, 255], [230, 148, 34, 255], [230, 148, 34, 255], [42, 204, 164, 255], [128, 0, 128, 255], [205, 62, 78, 255], [205, 62, 78, 255], [220, 248, 164, 255], [220, 248, 164, 255], [0, 225, 0, 255], [245, 245, 245, 255], [0, 200, 221, 255], [103, 255, 255, 255], [103, 255, 255, 255], [220, 216, 20, 255], [196, 58, 250, 255], [220, 216, 20, 255], [0, 200, 200, 255], [196, 58, 250, 255], [234, 169, 30, 255], [165, 42, 42, 255], [165, 42, 42, 255], [204, 182, 142, 255], [255, 165, 0, 255], [236, 13, 176, 255], [236, 13, 176, 255], [160, 32, 240, 255], [255, 165, 0, 255], [200, 70, 255, 255], [120, 18, 134, 255], [160, 32, 240, 255], [120, 18, 134, 255], [13, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [12, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [164, 108, 226, 255], [120, 190, 150, 255]], 'sharedGMMParameters': [GMMparameter(mergedName='Unknown', numberOfComponents=1, searchStrings=['Unknown', 'Skull']), GMMparameter(mergedName='GlobalWM', numberOfComponents=1, searchStrings=['White', 'Brain-Stem', 'VentralDC', 'Optic-Chiasm', 'Thalamus', 'Pallidum']), GMMparameter(mergedName='GlobalGM', numberOfComponents=1, searchStrings=['Cortex', 'Caudate', 'Hippocampus', 'Amygdala', 'Accumbens', 'hypointensities', 'Thalamus']), GMMparameter(mergedName='GlobalCSF_messy', numberOfComponents=1, searchStrings=['CSF', 'vessel', 'choroid-plexus', 'Fluid']), GMMparameter(mergedName='GlobalCSF_clean', numberOfComponents=1, searchStrings=['Ventricle', 'Inf-Lat-Vent', 'Fluid']), GMMparameter(mergedName='Putamen', numberOfComponents=1, searchStrings=['Putamen']), GMMparameter(mergedName='Soft', numberOfComponents=3, searchStrings=['Soft'])], 'useDiagonalCovarianceMatrices': True, 'maskingProbabilityThreshold': 0.5, 'maskingDistance': 10.0, 'K': 0.1, 'biasFieldSmoothingKernelSize': 50, 'whiteMatterAndCortexSmoothingSigma': 0} optimizationOptions: {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz', 'targetDownsampledVoxelSpacing': 2.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}, {'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ##---------------------------------------------- Samsegment Options ##---------------------------------------------- output directory: ../results_samseg_long/5771302 input images: 5771302/5771302_tp1_t1_reg.mgz modelSpecifications: {'FreeSurferLabels': [0, 165, 258, 16, 24, 8, 47, 15, 259, 3, 42, 7, 46, 41, 2, 63, 54, 18, 53, 44, 17, 31, 5, 85, 60, 28, 14, 26, 12, 51, 62, 58, 77, 4, 30, 43, 52, 11, 49, 13, 50, 10, 80, 72], 'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'names': ['Unknown', 'Skull', 'Soft_Nonbrain_Tissue', 'Brain-Stem', 'CSF', 'Left-Cerebellum-Cortex', 'Right-Cerebellum-Cortex', '4th-Ventricle', 'Fluid_Inside_Eyes', 'Left-Cerebral-Cortex', 'Right-Cerebral-Cortex', 'Left-Cerebellum-White-Matter', 'Right-Cerebellum-White-Matter', 'Right-Cerebral-White-Matter', 'Left-Cerebral-White-Matter', 'Right-choroid-plexus', 'Right-Amygdala', 'Left-Amygdala', 'Right-Hippocampus', 'Right-Inf-Lat-Vent', 'Left-Hippocampus', 'Left-choroid-plexus', 'Left-Inf-Lat-Vent', 'Optic-Chiasm', 'Right-VentralDC', 'Left-VentralDC', '3rd-Ventricle', 'Left-Accumbens-area', 'Left-Putamen', 'Right-Putamen', 'Right-vessel', 'Right-Accumbens-area', 'WM-hypointensities', 'Left-Lateral-Ventricle', 'Left-vessel', 'Right-Lateral-Ventricle', 'Right-Pallidum', 'Left-Caudate', 'Right-Thalamus', 'Left-Pallidum', 'Right-Caudate', 'Left-Thalamus', 'non-WM-hypointensities', '5th-Ventricle'], 'colors': [[0, 0, 0, 0], [255, 165, 0, 255], [128, 128, 128, 255], [119, 159, 176, 255], [60, 60, 60, 255], [230, 148, 34, 255], [230, 148, 34, 255], [42, 204, 164, 255], [128, 0, 128, 255], [205, 62, 78, 255], [205, 62, 78, 255], [220, 248, 164, 255], [220, 248, 164, 255], [0, 225, 0, 255], [245, 245, 245, 255], [0, 200, 221, 255], [103, 255, 255, 255], [103, 255, 255, 255], [220, 216, 20, 255], [196, 58, 250, 255], [220, 216, 20, 255], [0, 200, 200, 255], [196, 58, 250, 255], [234, 169, 30, 255], [165, 42, 42, 255], [165, 42, 42, 255], [204, 182, 142, 255], [255, 165, 0, 255], [236, 13, 176, 255], [236, 13, 176, 255], [160, 32, 240, 255], [255, 165, 0, 255], [200, 70, 255, 255], [120, 18, 134, 255], [160, 32, 240, 255], [120, 18, 134, 255], [13, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [12, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [164, 108, 226, 255], [120, 190, 150, 255]], 'sharedGMMParameters': [GMMparameter(mergedName='Unknown', numberOfComponents=1, searchStrings=['Unknown', 'Skull']), GMMparameter(mergedName='GlobalWM', numberOfComponents=1, searchStrings=['White', 'Brain-Stem', 'VentralDC', 'Optic-Chiasm', 'Thalamus', 'Pallidum']), GMMparameter(mergedName='GlobalGM', numberOfComponents=1, searchStrings=['Cortex', 'Caudate', 'Hippocampus', 'Amygdala', 'Accumbens', 'hypointensities', 'Thalamus']), GMMparameter(mergedName='GlobalCSF_messy', numberOfComponents=1, searchStrings=['CSF', 'vessel', 'choroid-plexus', 'Fluid']), GMMparameter(mergedName='GlobalCSF_clean', numberOfComponents=1, searchStrings=['Ventricle', 'Inf-Lat-Vent', 'Fluid']), GMMparameter(mergedName='Putamen', numberOfComponents=1, searchStrings=['Putamen']), GMMparameter(mergedName='Soft', numberOfComponents=3, searchStrings=['Soft'])], 'useDiagonalCovarianceMatrices': True, 'maskingProbabilityThreshold': 0.5, 'maskingDistance': 10.0, 'K': 0.1, 'biasFieldSmoothingKernelSize': 50, 'whiteMatterAndCortexSmoothingSigma': 0} optimizationOptions: {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz', 'targetDownsampledVoxelSpacing': 2.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}, {'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ##---------------------------------------------- Samsegment Options ##---------------------------------------------- output directory: ../results_samseg_long/5771302 input images: 5771302/5771302_tp2_t1_reg.mgz modelSpecifications: {'FreeSurferLabels': [0, 165, 258, 16, 24, 8, 47, 15, 259, 3, 42, 7, 46, 41, 2, 63, 54, 18, 53, 44, 17, 31, 5, 85, 60, 28, 14, 26, 12, 51, 62, 58, 77, 4, 30, 43, 52, 11, 49, 13, 50, 10, 80, 72], 'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'names': ['Unknown', 'Skull', 'Soft_Nonbrain_Tissue', 'Brain-Stem', 'CSF', 'Left-Cerebellum-Cortex', 'Right-Cerebellum-Cortex', '4th-Ventricle', 'Fluid_Inside_Eyes', 'Left-Cerebral-Cortex', 'Right-Cerebral-Cortex', 'Left-Cerebellum-White-Matter', 'Right-Cerebellum-White-Matter', 'Right-Cerebral-White-Matter', 'Left-Cerebral-White-Matter', 'Right-choroid-plexus', 'Right-Amygdala', 'Left-Amygdala', 'Right-Hippocampus', 'Right-Inf-Lat-Vent', 'Left-Hippocampus', 'Left-choroid-plexus', 'Left-Inf-Lat-Vent', 'Optic-Chiasm', 'Right-VentralDC', 'Left-VentralDC', '3rd-Ventricle', 'Left-Accumbens-area', 'Left-Putamen', 'Right-Putamen', 'Right-vessel', 'Right-Accumbens-area', 'WM-hypointensities', 'Left-Lateral-Ventricle', 'Left-vessel', 'Right-Lateral-Ventricle', 'Right-Pallidum', 'Left-Caudate', 'Right-Thalamus', 'Left-Pallidum', 'Right-Caudate', 'Left-Thalamus', 'non-WM-hypointensities', '5th-Ventricle'], 'colors': [[0, 0, 0, 0], [255, 165, 0, 255], [128, 128, 128, 255], [119, 159, 176, 255], [60, 60, 60, 255], [230, 148, 34, 255], [230, 148, 34, 255], [42, 204, 164, 255], [128, 0, 128, 255], [205, 62, 78, 255], [205, 62, 78, 255], [220, 248, 164, 255], [220, 248, 164, 255], [0, 225, 0, 255], [245, 245, 245, 255], [0, 200, 221, 255], [103, 255, 255, 255], [103, 255, 255, 255], [220, 216, 20, 255], [196, 58, 250, 255], [220, 216, 20, 255], [0, 200, 200, 255], [196, 58, 250, 255], [234, 169, 30, 255], [165, 42, 42, 255], [165, 42, 42, 255], [204, 182, 142, 255], [255, 165, 0, 255], [236, 13, 176, 255], [236, 13, 176, 255], [160, 32, 240, 255], [255, 165, 0, 255], [200, 70, 255, 255], [120, 18, 134, 255], [160, 32, 240, 255], [120, 18, 134, 255], [13, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [12, 48, 255, 255], [122, 186, 220, 255], [0, 118, 14, 255], [164, 108, 226, 255], [120, 190, 150, 255]], 'sharedGMMParameters': [GMMparameter(mergedName='Unknown', numberOfComponents=1, searchStrings=['Unknown', 'Skull']), GMMparameter(mergedName='GlobalWM', numberOfComponents=1, searchStrings=['White', 'Brain-Stem', 'VentralDC', 'Optic-Chiasm', 'Thalamus', 'Pallidum']), GMMparameter(mergedName='GlobalGM', numberOfComponents=1, searchStrings=['Cortex', 'Caudate', 'Hippocampus', 'Amygdala', 'Accumbens', 'hypointensities', 'Thalamus']), GMMparameter(mergedName='GlobalCSF_messy', numberOfComponents=1, searchStrings=['CSF', 'vessel', 'choroid-plexus', 'Fluid']), GMMparameter(mergedName='GlobalCSF_clean', numberOfComponents=1, searchStrings=['Ventricle', 'Inf-Lat-Vent', 'Fluid']), GMMparameter(mergedName='Putamen', numberOfComponents=1, searchStrings=['Putamen']), GMMparameter(mergedName='Soft', numberOfComponents=3, searchStrings=['Soft'])], 'useDiagonalCovarianceMatrices': True, 'maskingProbabilityThreshold': 0.5, 'maskingDistance': 10.0, 'K': 0.1, 'biasFieldSmoothingKernelSize': 50, 'whiteMatterAndCortexSmoothingSigma': 0} optimizationOptions: {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz', 'targetDownsampledVoxelSpacing': 2.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}, {'atlasFileName': '/opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} Unknown Unknown (100%) Skull (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Pallidum (100%) Right-Thalamus (50%) Left-Pallidum (100%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) WM-hypointensities (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) non-WM-hypointensities (100%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Soft Soft_Nonbrain_Tissue (100%) ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz targetDownsampledVoxelSpacing: 2.0 maximumNumberOfIterations: 100 estimateBiasField: True }, { depth: 2 atlasFileName: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz Transforming points Transforming points 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 ==================== iterationNumber: 0 EM converged! maximalDeformation=0.9071 minLogLikelihood=443297.9121 Total time spent: 0.8912 sec maximalDeformation=0.3027 minLogLikelihood=441931.7573 Total time spent: 0.2979 sec maximalDeformation=0.4653 minLogLikelihood=439276.0594 Total time spent: 0.2151 sec maximalDeformation=0.1333 minLogLikelihood=438752.6180 Total time spent: 0.2977 sec maximalDeformation=0.1337 minLogLikelihood=438385.6866 Total time spent: 0.4019 sec maximalDeformation=0.1811 minLogLikelihood=437987.1056 Total time spent: 0.2108 sec maximalDeformation=0.1353 minLogLikelihood=437850.0843 Total time spent: 0.5990 sec maximalDeformation=0.1020 minLogLikelihood=437157.5958 Total time spent: 0.2157 sec maximalDeformation=0.1519 minLogLikelihood=436002.7464 Total time spent: 0.2199 sec maximalDeformation=0.1581 minLogLikelihood=434710.3061 Total time spent: 0.5644 sec maximalDeformation=0.3320 minLogLikelihood=432680.0219 Total time spent: 0.2762 sec maximalDeformation=0.5437 minLogLikelihood=430198.2138 Total time spent: 0.2672 sec maximalDeformation=0.1939 minLogLikelihood=429288.7618 Total time spent: 0.3711 sec maximalDeformation=0.1210 minLogLikelihood=428507.9551 Total time spent: 0.3574 sec maximalDeformation=0.2386 minLogLikelihood=427739.2687 Total time spent: 0.2706 sec maximalDeformation=0.1383 minLogLikelihood=427576.2476 Total time spent: 0.2278 sec maximalDeformation=0.0966 minLogLikelihood=427388.8530 Total time spent: 0.3820 sec maximalDeformation=0.1696 minLogLikelihood=427188.7636 Total time spent: 0.2373 sec maximalDeformation=0.2510 minLogLikelihood=426747.3353 Total time spent: 0.2367 sec maximalDeformation=0.1852 minLogLikelihood=426389.4603 Total time spent: 0.3307 sec maximalDeformation=0.0000 minLogLikelihood=426389.4603 Total time spent: 0.0000 sec maximalDeformationApplied: 1.9174 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.5000 minLogLikelihood=388313.0975 Total time spent: 0.6103 sec maximalDeformation=0.0376 minLogLikelihood=388201.8323 Total time spent: 0.4342 sec maximalDeformation=0.2498 minLogLikelihood=387217.7159 Total time spent: 0.2309 sec maximalDeformation=0.6763 minLogLikelihood=384267.7567 Total time spent: 0.2294 sec maximalDeformation=0.3573 minLogLikelihood=383079.8033 Total time spent: 0.6525 sec maximalDeformation=0.0777 minLogLikelihood=382799.2819 Total time spent: 0.4551 sec maximalDeformation=0.1098 minLogLikelihood=382344.8425 Total time spent: 0.5449 sec maximalDeformation=0.0888 minLogLikelihood=382074.2695 Total time spent: 0.4641 sec maximalDeformation=0.1062 minLogLikelihood=381696.2493 Total time spent: 0.7174 sec maximalDeformation=0.0355 minLogLikelihood=381526.5691 Total time spent: 0.4484 sec maximalDeformation=0.0353 minLogLikelihood=381419.9268 Total time spent: 0.4512 sec maximalDeformation=0.0599 minLogLikelihood=381204.3017 Total time spent: 0.2304 sec maximalDeformation=0.0538 minLogLikelihood=381092.4388 Total time spent: 0.4601 sec maximalDeformation=0.0877 minLogLikelihood=380899.0057 Total time spent: 0.4267 sec maximalDeformation=0.0662 minLogLikelihood=380775.1772 Total time spent: 0.2503 sec maximalDeformation=0.0264 minLogLikelihood=380692.9348 Total time spent: 0.3788 sec maximalDeformation=0.0610 minLogLikelihood=380591.3554 Total time spent: 0.2323 sec maximalDeformation=0.0545 minLogLikelihood=380542.1929 Total time spent: 0.2944 sec maximalDeformation=0.0511 minLogLikelihood=380418.3448 Total time spent: 0.2471 sec maximalDeformation=0.0451 minLogLikelihood=380370.1186 Total time spent: 0.2303 sec maximalDeformation=0.0000 minLogLikelihood=380370.1186 Total time spent: 0.0000 sec maximalDeformationApplied: 1.6544 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=0.6613 minLogLikelihood=379780.4295 Total time spent: 0.7036 sec maximalDeformation=0.0865 minLogLikelihood=379572.9126 Total time spent: 0.1998 sec maximalDeformation=0.2359 minLogLikelihood=378851.3538 Total time spent: 0.2804 sec maximalDeformation=0.1839 minLogLikelihood=378243.5900 Total time spent: 0.3501 sec maximalDeformation=0.1536 minLogLikelihood=377653.7470 Total time spent: 0.3086 sec maximalDeformation=0.3245 minLogLikelihood=376560.4635 Total time spent: 0.2397 sec maximalDeformation=0.1736 minLogLikelihood=376011.3407 Total time spent: 0.3389 sec maximalDeformation=0.0629 minLogLikelihood=375753.2420 Total time spent: 0.4296 sec maximalDeformation=0.0897 minLogLikelihood=375336.9900 Total time spent: 0.3404 sec maximalDeformation=0.1642 minLogLikelihood=374637.6952 Total time spent: 0.3119 sec maximalDeformation=0.0832 minLogLikelihood=374288.0476 Total time spent: 0.4455 sec maximalDeformation=0.1105 minLogLikelihood=373902.1494 Total time spent: 0.3114 sec maximalDeformation=0.2536 minLogLikelihood=373105.6723 Total time spent: 0.2903 sec maximalDeformation=0.2571 minLogLikelihood=372445.6612 Total time spent: 0.3796 sec maximalDeformation=0.3194 minLogLikelihood=371611.1814 Total time spent: 0.2585 sec maximalDeformation=0.2520 minLogLikelihood=371199.8114 Total time spent: 0.5212 sec maximalDeformation=0.2837 minLogLikelihood=370779.9950 Total time spent: 0.2282 sec maximalDeformation=0.2757 minLogLikelihood=370366.7407 Total time spent: 0.2289 sec maximalDeformation=0.1504 minLogLikelihood=370119.2795 Total time spent: 0.4269 sec maximalDeformation=0.2790 minLogLikelihood=369826.0478 Total time spent: 0.3236 sec maximalDeformation=0.0000 minLogLikelihood=369826.0478 Total time spent: 0.0000 sec maximalDeformationApplied: 1.9137 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=0.5000 minLogLikelihood=368589.1612 Total time spent: 0.5313 sec maximalDeformation=0.1102 minLogLikelihood=368434.8485 Total time spent: 0.4338 sec maximalDeformation=0.2346 minLogLikelihood=368114.1436 Total time spent: 0.2412 sec maximalDeformation=0.2370 minLogLikelihood=367802.7717 Total time spent: 0.4125 sec maximalDeformation=0.2040 minLogLikelihood=367577.5340 Total time spent: 0.2383 sec maximalDeformation=0.1634 minLogLikelihood=367404.6956 Total time spent: 0.3877 sec maximalDeformation=0.2348 minLogLikelihood=367288.8394 Total time spent: 0.2148 sec maximalDeformation=0.0948 minLogLikelihood=367255.7661 Total time spent: 0.3196 sec maximalDeformation=0.1764 minLogLikelihood=367173.6457 Total time spent: 0.2252 sec maximalDeformation=0.0479 minLogLikelihood=367110.6362 Total time spent: 0.2338 sec maximalDeformation=0.2270 minLogLikelihood=366871.4355 Total time spent: 0.7769 sec maximalDeformation=0.1189 minLogLikelihood=366773.1421 Total time spent: 0.5318 sec maximalDeformation=0.2185 minLogLikelihood=366667.1054 Total time spent: 0.2549 sec maximalDeformation=0.1493 minLogLikelihood=366619.0237 Total time spent: 0.3116 sec maximalDeformation=0.1290 minLogLikelihood=366555.7976 Total time spent: 0.2410 sec maximalDeformation=0.0807 minLogLikelihood=366543.1624 Total time spent: 0.4541 sec maximalDeformation=0.0176 minLogLikelihood=366535.6137 Total time spent: 0.2455 sec maximalDeformation=0.1184 minLogLikelihood=366499.5877 Total time spent: 0.4671 sec maximalDeformation=0.1324 minLogLikelihood=366403.5504 Total time spent: 0.2475 sec maximalDeformation=0.0112 minLogLikelihood=366394.9854 Total time spent: 0.7061 sec maximalDeformation=0.0000 minLogLikelihood=366394.9854 Total time spent: 0.0000 sec maximalDeformationApplied: 1.7126 ======================================================= iterationNumber: 4 EM converged! maximalDeformation=0.3791 minLogLikelihood=366309.8674 Total time spent: 0.8090 sec maximalDeformation=0.2824 minLogLikelihood=366014.2360 Total time spent: 0.4978 sec maximalDeformation=0.3652 minLogLikelihood=365757.4094 Total time spent: 0.2470 sec maximalDeformation=0.0839 minLogLikelihood=365725.1368 Total time spent: 0.3902 sec maximalDeformation=0.0960 minLogLikelihood=365692.2324 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Total time spent: 0.2892 sec maximalDeformation=0.1326 minLogLikelihood=365634.5251 Total time spent: 0.2659 sec maximalDeformation=0.0704 minLogLikelihood=365587.3820 Total time spent: 0.7980 sec maximalDeformation=0.1035 minLogLikelihood=365512.3704 Total time spent: 0.4819 sec maximalDeformation=0.2092 minLogLikelihood=365375.2244 Total time spent: 0.2797 sec maximalDeformation=0.0504 minLogLikelihood=365345.4923 Total time spent: 0.8937 sec maximalDeformation=0.0814 minLogLikelihood=365304.6689 Total time spent: 0.2613 sec maximalDeformation=0.0610 minLogLikelihood=365271.0897 Total time spent: 0.2504 sec maximalDeformation=0.1789 minLogLikelihood=365137.2490 Total time spent: 0.2590 sec maximalDeformation=0.0857 minLogLikelihood=365074.1466 Total time spent: 0.3392 sec maximalDeformation=0.1347 minLogLikelihood=364903.6323 Total time spent: 0.2794 sec maximalDeformation=0.1029 minLogLikelihood=364782.3007 Total time spent: 0.5338 sec maximalDeformation=0.1516 minLogLikelihood=364612.6769 Total time spent: 0.4702 sec maximalDeformation=0.1988 minLogLikelihood=364397.5094 Total time spent: 0.4310 sec maximalDeformation=0.0935 minLogLikelihood=364255.2868 Total time spent: 0.4271 sec maximalDeformation=0.2328 minLogLikelihood=364009.9514 Total time spent: 0.3116 sec maximalDeformation=0.0000 minLogLikelihood=364009.9514 Total time spent: 0.0000 sec maximalDeformationApplied: 1.2721 ======================================================= iterationNumber: 5 EM converged! maximalDeformation=0.2500 minLogLikelihood=363908.7935 Total time spent: 0.8822 sec maximalDeformation=0.0496 minLogLikelihood=363861.4980 Total time spent: 0.4646 sec maximalDeformation=0.3157 minLogLikelihood=363611.1947 Total time spent: 0.3986 sec maximalDeformation=0.2609 minLogLikelihood=363462.2117 Total time spent: 0.3297 sec maximalDeformation=0.1639 minLogLikelihood=363366.8517 Total time spent: 0.4254 sec maximalDeformation=0.1687 minLogLikelihood=363309.8545 Total time spent: 0.6028 sec maximalDeformation=0.0973 minLogLikelihood=363266.6650 Total time spent: 0.3176 sec maximalDeformation=0.0752 minLogLikelihood=363234.4816 Total time spent: 0.2518 sec maximalDeformation=0.1314 minLogLikelihood=363132.6009 Total time spent: 0.2509 sec maximalDeformation=0.2528 minLogLikelihood=363120.7781 Total time spent: 0.2528 sec maximalDeformation=0.1428 minLogLikelihood=363022.3859 Total time spent: 0.2776 sec maximalDeformation=0.1230 minLogLikelihood=362960.0301 Total time spent: 0.2544 sec maximalDeformation=0.1249 minLogLikelihood=362865.0485 Total time spent: 0.4220 sec maximalDeformation=0.1453 minLogLikelihood=362758.7612 Total time spent: 0.3779 sec maximalDeformation=0.1113 minLogLikelihood=362693.7408 Total time spent: 0.4253 sec maximalDeformation=0.2328 minLogLikelihood=362603.5017 Total time spent: 0.2663 sec maximalDeformation=0.1556 minLogLikelihood=362541.3005 Total time spent: 0.4229 sec maximalDeformation=0.0941 minLogLikelihood=362475.6850 Total time spent: 0.2760 sec maximalDeformation=0.1958 minLogLikelihood=362390.6708 Total time spent: 0.2741 sec maximalDeformation=0.1150 minLogLikelihood=362312.4290 Total time spent: 0.3194 sec maximalDeformation=0.0000 minLogLikelihood=362312.4290 Total time spent: 0.0000 sec maximalDeformationApplied: 1.2316 ======================================================= iterationNumber: 6 EM converged! maximalDeformation=0.2500 minLogLikelihood=362222.9206 Total time spent: 0.6475 sec maximalDeformation=0.0779 minLogLikelihood=362168.7077 Total time spent: 0.2559 sec maximalDeformation=0.1764 minLogLikelihood=362070.6903 Total time spent: 0.3284 sec maximalDeformation=0.0996 minLogLikelihood=362007.4421 Total time spent: 0.3583 sec maximalDeformation=0.1467 minLogLikelihood=361939.6767 Total time spent: 0.3775 sec maximalDeformation=0.1696 minLogLikelihood=361899.3047 Total time spent: 0.4462 sec maximalDeformation=0.0753 minLogLikelihood=361880.8956 Total time spent: 0.2907 sec maximalDeformation=0.0718 minLogLikelihood=361857.2721 Total time spent: 0.2835 sec maximalDeformation=0.0868 minLogLikelihood=361823.3173 Total time spent: 0.3839 sec maximalDeformation=0.0415 minLogLikelihood=361804.1046 Total time spent: 0.3528 sec maximalDeformation=0.0351 minLogLikelihood=361782.2507 Total time spent: 0.3583 sec maximalDeformation=0.1368 minLogLikelihood=361709.7766 Total time spent: 0.4491 sec maximalDeformation=0.0762 minLogLikelihood=361693.5492 Total time spent: 0.5556 sec maximalDeformation=0.1279 minLogLikelihood=361665.2171 Total time spent: 0.2748 sec maximalDeformation=0.0996 minLogLikelihood=361602.5673 Total time spent: 0.2880 sec maximalDeformation=0.2049 minLogLikelihood=361483.1855 Total time spent: 0.2922 sec maximalDeformation=0.0864 minLogLikelihood=361410.9223 Total time spent: 0.4374 sec maximalDeformation=0.1160 minLogLikelihood=361336.4176 Total time spent: 0.3839 sec maximalDeformation=0.0435 minLogLikelihood=361309.1504 Total time spent: 0.2866 sec maximalDeformation=0.1222 minLogLikelihood=361252.1297 Total time spent: 0.2297 sec maximalDeformation=0.0000 minLogLikelihood=361252.1297 Total time spent: 0.0000 sec maximalDeformationApplied: 1.0830 ======================================================= iterationNumber: 7 EM converged! maximalDeformation=0.5000 minLogLikelihood=361136.1418 Total time spent: 0.5328 sec maximalDeformation=0.1551 minLogLikelihood=361110.6277 Total time spent: 0.3186 sec maximalDeformation=0.1228 minLogLikelihood=361086.8121 Total time spent: 0.2044 sec maximalDeformation=0.1821 minLogLikelihood=361034.9358 Total time spent: 0.2074 sec maximalDeformation=0.1487 minLogLikelihood=360994.9206 Total time spent: 0.2901 sec maximalDeformation=0.0829 minLogLikelihood=360944.9499 Total time spent: 0.2125 sec maximalDeformation=0.2595 minLogLikelihood=360933.3207 Total time spent: 0.2144 sec maximalDeformation=0.0929 minLogLikelihood=360887.2532 Total time spent: 0.2168 sec maximalDeformation=0.1034 minLogLikelihood=360836.3328 Total time spent: 0.2201 sec maximalDeformation=0.1271 minLogLikelihood=360787.0123 Total time spent: 0.2230 sec maximalDeformation=0.1311 minLogLikelihood=360745.0268 Total time spent: 0.2254 sec maximalDeformation=0.1058 minLogLikelihood=360736.1240 Total time spent: 0.5211 sec maximalDeformation=0.1324 minLogLikelihood=360726.6281 Total time spent: 0.2294 sec maximalDeformation=0.0407 minLogLikelihood=360714.9695 Total time spent: 0.2302 sec maximalDeformation=0.0767 minLogLikelihood=360686.9702 Total time spent: 0.2297 sec maximalDeformation=0.0970 minLogLikelihood=360631.6966 Total time spent: 0.2319 sec maximalDeformation=0.1333 minLogLikelihood=360606.2004 Total time spent: 0.4266 sec maximalDeformation=0.0416 minLogLikelihood=360581.7531 Total time spent: 0.2320 sec maximalDeformation=0.0992 minLogLikelihood=360519.7917 Total time spent: 0.2303 sec maximalDeformation=0.1301 minLogLikelihood=360451.2786 Total time spent: 0.2304 sec maximalDeformation=0.0000 minLogLikelihood=360451.2786 Total time spent: 0.0000 sec maximalDeformationApplied: 0.7936 ======================================================= iterationNumber: 8 EM converged! maximalDeformation=0.1610 minLogLikelihood=360397.0856 Total time spent: 0.7673 sec maximalDeformation=0.0928 minLogLikelihood=360371.6700 Total time spent: 0.2005 sec maximalDeformation=0.0982 minLogLikelihood=360338.6414 Total time spent: 0.2033 sec maximalDeformation=0.1374 minLogLikelihood=360308.9628 Total time spent: 0.2041 sec maximalDeformation=0.1148 minLogLikelihood=360303.4982 Total time spent: 0.3988 sec maximalDeformation=0.0551 minLogLikelihood=360295.3068 Total time spent: 0.2096 sec maximalDeformation=0.0226 minLogLikelihood=360289.1624 Total time spent: 0.2122 sec maximalDeformation=0.1176 minLogLikelihood=360268.0923 Total time spent: 0.3136 sec maximalDeformation=0.0882 minLogLikelihood=360249.1290 Total time spent: 0.2167 sec maximalDeformation=0.0960 minLogLikelihood=360238.3772 Total time spent: 0.2205 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0629 minLogLikelihood=360236.6356 Total time spent: 0.3417 sec maximalDeformation=0.1688 minLogLikelihood=360234.5746 Total time spent: 0.2256 sec maximalDeformation=0.0359 minLogLikelihood=360224.7985 Total time spent: 0.2287 sec maximalDeformation=0.1194 minLogLikelihood=360203.7157 Total time spent: 0.2273 sec maximalDeformation=0.1146 minLogLikelihood=360181.2129 Total time spent: 0.2278 sec maximalDeformation=0.1293 minLogLikelihood=360160.2679 Total time spent: 0.2282 sec maximalDeformation=0.1517 minLogLikelihood=360141.5114 Total time spent: 0.2302 sec maximalDeformation=0.0627 minLogLikelihood=360116.6412 Total time spent: 0.2272 sec maximalDeformation=0.0482 minLogLikelihood=360095.7011 Total time spent: 0.4919 sec maximalDeformation=0.1581 minLogLikelihood=360063.7397 Total time spent: 0.2270 sec maximalDeformation=0.0000 minLogLikelihood=360063.7397 Total time spent: 0.0000 sec maximalDeformationApplied: 0.7849 ======================================================= iterationNumber: 9 EM converged! maximalDeformation=0.5000 minLogLikelihood=360048.4122 Total time spent: 0.6026 sec maximalDeformation=0.1251 minLogLikelihood=360030.9467 Total time spent: 0.2009 sec maximalDeformation=0.2458 minLogLikelihood=360005.5014 Total time spent: 0.2031 sec maximalDeformation=0.1107 minLogLikelihood=359997.8881 Total time spent: 0.2825 sec maximalDeformation=0.0792 minLogLikelihood=359988.5568 Total time spent: 0.2083 sec maximalDeformation=0.0393 minLogLikelihood=359980.0149 Total time spent: 0.2110 sec maximalDeformation=0.1543 minLogLikelihood=359964.4226 Total time spent: 0.2139 sec maximalDeformation=0.0771 minLogLikelihood=359945.1856 Total time spent: 0.2167 sec maximalDeformation=0.0586 minLogLikelihood=359926.0255 Total time spent: 0.2129 sec maximalDeformation=0.0872 minLogLikelihood=359906.1247 Total time spent: 0.2108 sec maximalDeformation=0.1218 minLogLikelihood=359885.3925 Total time spent: 0.2129 sec maximalDeformation=0.0920 minLogLikelihood=359860.6427 Total time spent: 0.2156 sec maximalDeformation=0.0990 minLogLikelihood=359829.9435 Total time spent: 0.2263 sec maximalDeformation=0.0922 minLogLikelihood=359798.7403 Total time spent: 0.2244 sec maximalDeformation=0.1458 minLogLikelihood=359760.5253 Total time spent: 0.2314 sec maximalDeformation=0.1828 minLogLikelihood=359714.7212 Total time spent: 0.2258 sec maximalDeformation=0.1332 minLogLikelihood=359668.6982 Total time spent: 0.2309 sec maximalDeformation=0.0939 minLogLikelihood=359624.1484 Total time spent: 0.2246 sec maximalDeformation=0.0880 minLogLikelihood=359579.1872 Total time spent: 0.2323 sec maximalDeformation=0.1657 minLogLikelihood=359540.8104 Total time spent: 0.2340 sec maximalDeformation=0.0000 minLogLikelihood=359540.8104 Total time spent: 0.0000 sec maximalDeformationApplied: 1.0542 ======================================================= iterationNumber: 10 EM converged! maximalDeformation=0.2500 minLogLikelihood=359495.4308 Total time spent: 0.7596 sec maximalDeformation=0.1934 minLogLikelihood=359471.9675 Total time spent: 0.2157 sec maximalDeformation=0.0970 minLogLikelihood=359458.9490 Total time spent: 0.2062 sec maximalDeformation=0.1022 minLogLikelihood=359449.5631 Total time spent: 0.2043 sec maximalDeformation=0.1375 minLogLikelihood=359437.4606 Total time spent: 0.2063 sec maximalDeformation=0.1173 minLogLikelihood=359427.1345 Total time spent: 0.2036 sec maximalDeformation=0.1671 minLogLikelihood=359415.0712 Total time spent: 0.2034 sec maximalDeformation=0.1031 minLogLikelihood=359404.6295 Total time spent: 0.2053 sec maximalDeformation=0.0603 minLogLikelihood=359394.2138 Total time spent: 0.2023 sec maximalDeformation=0.0650 minLogLikelihood=359385.9402 Total time spent: 0.2011 sec maximalDeformation=0.0714 minLogLikelihood=359377.8887 Total time spent: 0.2040 sec maximalDeformation=0.0737 minLogLikelihood=359370.5009 Total time spent: 0.2063 sec maximalDeformation=0.0616 minLogLikelihood=359362.8654 Total time spent: 0.2111 sec maximalDeformation=0.0591 minLogLikelihood=359355.6240 Total time spent: 0.2106 sec maximalDeformation=0.0470 minLogLikelihood=359348.8721 Total time spent: 0.2104 sec maximalDeformation=0.0497 minLogLikelihood=359342.0747 Total time spent: 0.2089 sec maximalDeformation=0.0429 minLogLikelihood=359335.1587 Total time spent: 0.2110 sec maximalDeformation=0.0500 minLogLikelihood=359328.0881 Total time spent: 0.2155 sec maximalDeformation=0.0397 minLogLikelihood=359320.8084 Total time spent: 0.2176 sec maximalDeformation=0.0442 minLogLikelihood=359312.7966 Total time spent: 0.2091 sec maximalDeformation=0.0000 minLogLikelihood=359312.7966 Total time spent: 0.0000 sec maximalDeformationApplied: 1.1710 ======================================================= iterationNumber: 11 EM converged! maximalDeformation=0.1777 minLogLikelihood=359297.2460 Total time spent: 0.7502 sec maximalDeformation=0.0487 minLogLikelihood=359292.5290 Total time spent: 0.2017 sec maximalDeformation=0.0292 minLogLikelihood=359289.2332 Total time spent: 0.2140 sec maximalDeformation=0.0311 minLogLikelihood=359286.2952 Total time spent: 0.2056 sec maximalDeformation=0.0266 minLogLikelihood=359282.2979 Total time spent: 0.2096 sec maximalDeformation=0.0367 minLogLikelihood=359278.8005 Total time spent: 0.2107 sec maximalDeformation=0.0386 minLogLikelihood=359275.2625 Total time spent: 0.2129 sec maximalDeformation=0.0310 minLogLikelihood=359272.1995 Total time spent: 0.2167 sec maximalDeformation=0.0181 minLogLikelihood=359269.5548 Total time spent: 0.2179 sec maximalDeformation=0.0144 minLogLikelihood=359267.0748 Total time spent: 0.2206 sec maximalDeformation=0.0210 minLogLikelihood=359263.9075 Total time spent: 0.2241 sec maximalDeformation=0.0246 minLogLikelihood=359261.0059 Total time spent: 0.2260 sec maximalDeformation=0.0252 minLogLikelihood=359258.0634 Total time spent: 0.2290 sec maximalDeformation=0.0279 minLogLikelihood=359254.4148 Total time spent: 0.2281 sec maximalDeformation=0.0365 minLogLikelihood=359250.9711 Total time spent: 0.2283 sec maximalDeformation=0.0338 minLogLikelihood=359247.4145 Total time spent: 0.2281 sec maximalDeformation=0.0481 minLogLikelihood=359242.9309 Total time spent: 0.2283 sec maximalDeformation=0.0646 minLogLikelihood=359237.9163 Total time spent: 0.2288 sec maximalDeformation=0.0772 minLogLikelihood=359232.9020 Total time spent: 0.2310 sec maximalDeformation=0.0750 minLogLikelihood=359227.7708 Total time spent: 0.2277 sec maximalDeformation=0.0000 minLogLikelihood=359227.7708 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2805 ======================================================= iterationNumber: 12 EM converged! maximalDeformation=0.0593 minLogLikelihood=359218.4856 Total time spent: 0.7533 sec maximalDeformation=0.0160 minLogLikelihood=359215.0582 Total time spent: 0.2007 sec maximalDeformation=0.0194 minLogLikelihood=359212.3355 Total time spent: 0.2043 sec maximalDeformation=0.0146 minLogLikelihood=359210.3337 Total time spent: 0.2061 sec maximalDeformation=0.0182 minLogLikelihood=359207.8073 Total time spent: 0.2086 sec maximalDeformation=0.0218 minLogLikelihood=359205.9624 Total time spent: 0.2106 sec maximalDeformation=0.0118 minLogLikelihood=359203.9464 Total time spent: 0.2240 sec maximalDeformation=0.0151 minLogLikelihood=359201.9672 Total time spent: 0.2208 sec maximalDeformation=0.0173 minLogLikelihood=359200.3292 Total time spent: 0.2187 sec maximalDeformation=0.0143 minLogLikelihood=359198.4715 Total time spent: 0.2266 sec maximalDeformation=0.0196 minLogLikelihood=359196.4359 Total time spent: 0.2174 sec maximalDeformation=0.0230 minLogLikelihood=359194.4732 Total time spent: 0.2166 sec maximalDeformation=0.0297 minLogLikelihood=359192.4265 Total time spent: 0.2204 sec maximalDeformation=0.0322 minLogLikelihood=359190.2985 Total time spent: 0.2198 sec maximalDeformation=0.0448 minLogLikelihood=359188.2898 Total time spent: 0.2199 sec Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level1.txt.gz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.005 MaximalDeformationStopCriterion: 0.005 Verbose: 1 [BRACKETING] Found a really good solution -- no need for zooming: 1 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 7.08161 ----------------------- [BRACKETING] Hit a really bad solution -- ready for zooming: 2.52557 [ZOOMING] Zooming with low=0 and high=2.52557 bisected: 1.26278 bisected: 0.631392 [ZOOMING] Found a good solution: 0.631392 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.372225 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.195121 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.170435 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0377132 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0897319 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0266412 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.0125887 ----------------------- [BRACKETING] Found a really good solution -- no need for zooming: 0.00457452 ----------------------- Optimizer: maximalDeformation is too small; stopping 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0325 minLogLikelihood=359186.3600 Total time spent: 0.2209 sec maximalDeformation=0.0376 minLogLikelihood=359184.0492 Total time spent: 0.2192 sec maximalDeformation=0.0388 minLogLikelihood=359181.8734 Total time spent: 0.2199 sec maximalDeformation=0.0284 minLogLikelihood=359179.4701 Total time spent: 0.2208 sec maximalDeformation=0.0315 minLogLikelihood=359176.6789 Total time spent: 0.2199 sec maximalDeformation=0.0000 minLogLikelihood=359176.6789 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3062 ======================================================= iterationNumber: 0 EM converged! maximalDeformation=0.5000 minLogLikelihood=2785024.6318 Total time spent: 2.5640 sec maximalDeformation=0.2282 minLogLikelihood=2779680.2079 Total time spent: 0.9394 sec maximalDeformation=0.5608 minLogLikelihood=2765222.6214 Total time spent: 0.9052 sec maximalDeformation=0.1870 minLogLikelihood=2760733.9888 Total time spent: 1.1244 sec maximalDeformation=0.1163 minLogLikelihood=2758677.3799 Total time spent: 1.3757 sec maximalDeformation=0.2064 minLogLikelihood=2755537.0825 Total time spent: 1.7191 sec maximalDeformation=0.2860 minLogLikelihood=2752939.3084 Total time spent: 1.0232 sec maximalDeformation=0.0313 minLogLikelihood=2752517.2142 Total time spent: 2.5395 sec maximalDeformation=0.1318 minLogLikelihood=2752327.9561 Total time spent: 0.6518 sec maximalDeformation=0.1331 minLogLikelihood=2751022.9129 Total time spent: 0.6537 sec maximalDeformation=0.2076 minLogLikelihood=2749549.7028 Total time spent: 1.4049 sec maximalDeformation=0.1527 minLogLikelihood=2748803.9357 Total time spent: 0.6632 sec maximalDeformation=0.3759 minLogLikelihood=2747586.8517 Total time spent: 0.6696 sec maximalDeformation=0.0829 minLogLikelihood=2746992.7747 Total time spent: 0.6669 sec maximalDeformation=0.3822 minLogLikelihood=2744995.6246 Total time spent: 0.7193 sec maximalDeformation=0.2234 minLogLikelihood=2743490.2082 Total time spent: 0.9214 sec maximalDeformation=1.1564 minLogLikelihood=2738945.5357 Total time spent: 0.7032 sec maximalDeformation=0.1039 minLogLikelihood=2738666.0486 Total time spent: 1.7861 sec maximalDeformation=0.2737 minLogLikelihood=2738343.1230 Total time spent: 0.6635 sec maximalDeformation=0.1053 minLogLikelihood=2738001.5096 Total time spent: 0.6697 sec maximalDeformation=0.0000 minLogLikelihood=2738001.5096 Total time spent: 0.0000 sec maximalDeformationApplied: 2.4214 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=1.0000 minLogLikelihood=2735777.6251 Total time spent: 2.4024 sec maximalDeformation=0.3608 minLogLikelihood=2735068.2461 Total time spent: 0.7710 sec maximalDeformation=0.1022 minLogLikelihood=2734152.2389 Total time spent: 1.5763 sec maximalDeformation=0.3640 minLogLikelihood=2731388.2210 Total time spent: 0.9330 sec maximalDeformation=0.1405 minLogLikelihood=2730269.9307 Total time spent: 1.0193 sec maximalDeformation=0.0316 minLogLikelihood=2730122.7663 Total time spent: 2.1885 sec maximalDeformation=0.3099 minLogLikelihood=2727727.2055 Total time spent: 0.6476 sec maximalDeformation=0.1492 minLogLikelihood=2726668.4526 Total time spent: 1.2503 sec maximalDeformation=0.0324 minLogLikelihood=2726610.3477 Total time spent: 1.7456 sec maximalDeformation=0.0870 minLogLikelihood=2726298.1113 Total time spent: 0.7094 sec maximalDeformation=0.2562 minLogLikelihood=2725768.8932 Total time spent: 0.7070 sec maximalDeformation=0.4741 minLogLikelihood=2724576.2273 Total time spent: 1.3237 sec maximalDeformation=0.2352 minLogLikelihood=2724288.4090 Total time spent: 0.6750 sec maximalDeformation=0.3871 minLogLikelihood=2723380.0039 Total time spent: 0.6729 sec maximalDeformation=0.4164 minLogLikelihood=2723099.5954 Total time spent: 0.6681 sec maximalDeformation=0.3086 minLogLikelihood=2722740.3595 Total time spent: 1.1746 sec maximalDeformation=0.1156 minLogLikelihood=2722309.3105 Total time spent: 0.6642 sec maximalDeformation=0.2507 minLogLikelihood=2721712.6803 Total time spent: 1.8053 sec maximalDeformation=0.3850 minLogLikelihood=2720549.8891 Total time spent: 0.7095 sec maximalDeformation=0.0604 minLogLikelihood=2720303.3921 Total time spent: 2.3359 sec maximalDeformation=0.0000 minLogLikelihood=2720303.3921 Total time spent: 0.0000 sec maximalDeformationApplied: 3.5469 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=0.2500 minLogLikelihood=2719567.6554 Total time spent: 2.5195 sec maximalDeformation=0.3866 minLogLikelihood=2717981.3026 Total time spent: 1.6202 sec maximalDeformation=0.6097 minLogLikelihood=2715866.3163 Total time spent: 1.9354 sec maximalDeformation=0.3171 minLogLikelihood=2714932.8037 Total time spent: 0.8818 sec maximalDeformation=0.0793 minLogLikelihood=2714845.5203 Total time spent: 1.0971 sec maximalDeformation=0.3330 minLogLikelihood=2714073.2881 Total time spent: 0.6289 sec maximalDeformation=0.2565 minLogLikelihood=2713797.5740 Total time spent: 1.8121 sec maximalDeformation=0.0623 minLogLikelihood=2713520.4453 Total time spent: 0.6410 sec maximalDeformation=0.3671 minLogLikelihood=2713017.7944 Total time spent: 0.6470 sec maximalDeformation=0.4643 minLogLikelihood=2712844.3730 Total time spent: 1.3159 sec maximalDeformation=0.0627 minLogLikelihood=2712574.8528 Total time spent: 0.8053 sec maximalDeformation=0.0335 minLogLikelihood=2712494.1060 Total time spent: 0.8382 sec maximalDeformation=0.1748 minLogLikelihood=2712049.6695 Total time spent: 1.4547 sec maximalDeformation=0.6342 minLogLikelihood=2711055.1562 Total time spent: 0.8047 sec maximalDeformation=0.9773 minLogLikelihood=2708886.1160 Total time spent: 0.9565 sec maximalDeformation=0.1336 minLogLikelihood=2708448.3388 Total time spent: 1.8248 sec maximalDeformation=0.0763 minLogLikelihood=2708323.7313 Total time spent: 1.6466 sec maximalDeformation=0.1369 minLogLikelihood=2708160.6472 Total time spent: 0.8444 sec maximalDeformation=0.3690 minLogLikelihood=2707823.3724 Total time spent: 1.6555 sec maximalDeformation=0.1840 minLogLikelihood=2707585.4072 Total time spent: 1.4008 sec maximalDeformation=0.0000 minLogLikelihood=2707585.4072 Total time spent: 0.0000 sec maximalDeformationApplied: 4.2800 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=1.0000 minLogLikelihood=2705927.8433 Total time spent: 1.9090 sec maximalDeformation=0.0942 minLogLikelihood=2705262.1769 Total time spent: 0.6548 sec maximalDeformation=0.2581 minLogLikelihood=2703828.6509 Total time spent: 0.8469 sec maximalDeformation=0.2679 minLogLikelihood=2702407.0016 Total time spent: 1.3761 sec maximalDeformation=0.3560 minLogLikelihood=2700966.2626 Total time spent: 1.0713 sec maximalDeformation=0.2685 minLogLikelihood=2699999.2719 Total time spent: 0.8271 sec maximalDeformation=0.0796 minLogLikelihood=2699883.0696 Total time spent: 1.4437 sec maximalDeformation=0.1906 minLogLikelihood=2699285.4630 Total time spent: 1.2317 sec maximalDeformation=0.1068 minLogLikelihood=2699108.2627 Total time spent: 1.7982 sec maximalDeformation=0.2395 minLogLikelihood=2698721.6526 Total time spent: 0.6494 sec maximalDeformation=0.1634 minLogLikelihood=2698570.9511 Total time spent: 1.2493 sec maximalDeformation=0.1443 minLogLikelihood=2698053.8895 Total time spent: 0.6750 sec maximalDeformation=0.2337 minLogLikelihood=2697477.3262 Total time spent: 0.6615 sec maximalDeformation=0.1753 minLogLikelihood=2697016.9654 Total time spent: 1.0245 sec maximalDeformation=0.0686 minLogLikelihood=2696700.1143 Total time spent: 1.1591 sec maximalDeformation=0.4378 minLogLikelihood=2695828.2023 Total time spent: 0.7537 sec maximalDeformation=0.0954 minLogLikelihood=2695461.6972 Total time spent: 0.8491 sec maximalDeformation=0.0864 minLogLikelihood=2695206.9772 Total time spent: 0.8478 sec maximalDeformation=0.3615 minLogLikelihood=2694433.8878 Total time spent: 1.2640 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0652 minLogLikelihood=2694117.9784 Total time spent: 0.6628 sec maximalDeformation=0.0000 minLogLikelihood=2694117.9784 Total time spent: 0.0000 sec maximalDeformationApplied: 2.3790 ======================================================= iterationNumber: 4 EM converged! maximalDeformation=0.2500 minLogLikelihood=2692966.4041 Total time spent: 2.6302 sec maximalDeformation=0.3172 minLogLikelihood=2691891.3611 Total time spent: 0.6005 sec maximalDeformation=0.1782 minLogLikelihood=2691369.7807 Total time spent: 1.5647 sec maximalDeformation=0.2562 minLogLikelihood=2690640.5097 Total time spent: 1.2634 sec maximalDeformation=0.1759 minLogLikelihood=2690244.0310 Total time spent: 1.3267 sec maximalDeformation=0.1076 minLogLikelihood=2690024.8733 Total time spent: 0.6308 sec maximalDeformation=0.0987 minLogLikelihood=2689797.8910 Total time spent: 1.2344 sec maximalDeformation=0.0929 minLogLikelihood=2689547.9195 Total time spent: 0.6485 sec maximalDeformation=0.1925 minLogLikelihood=2689307.1141 Total time spent: 1.5412 sec maximalDeformation=0.0726 minLogLikelihood=2689166.4025 Total time spent: 0.6555 sec maximalDeformation=0.2629 minLogLikelihood=2688864.2965 Total time spent: 1.2542 sec maximalDeformation=0.2490 minLogLikelihood=2688369.1006 Total time spent: 0.7524 sec maximalDeformation=0.4646 minLogLikelihood=2687613.7474 Total time spent: 0.7731 sec maximalDeformation=0.0761 minLogLikelihood=2687483.8106 Total time spent: 2.3355 sec maximalDeformation=0.1213 minLogLikelihood=2687291.4186 Total time spent: 0.6714 sec maximalDeformation=0.2118 minLogLikelihood=2687081.0485 Total time spent: 1.2788 sec maximalDeformation=0.2752 minLogLikelihood=2686781.4935 Total time spent: 0.6689 sec maximalDeformation=0.3338 minLogLikelihood=2686596.9506 Total time spent: 1.2857 sec maximalDeformation=0.1431 minLogLikelihood=2686404.0372 Total time spent: 0.6681 sec maximalDeformation=0.2310 minLogLikelihood=2686271.9509 Total time spent: 0.6641 sec maximalDeformation=0.0000 minLogLikelihood=2686271.9509 Total time spent: 0.0000 sec maximalDeformationApplied: 1.9525 ======================================================= iterationNumber: 5 EM converged! maximalDeformation=0.5000 minLogLikelihood=2686047.2366 Total time spent: 2.1248 sec maximalDeformation=0.1580 minLogLikelihood=2685846.6551 Total time spent: 0.6637 sec maximalDeformation=0.0744 minLogLikelihood=2685678.2787 Total time spent: 0.6728 sec maximalDeformation=0.4632 minLogLikelihood=2685032.0013 Total time spent: 0.7936 sec maximalDeformation=0.1191 minLogLikelihood=2684885.6223 Total time spent: 1.4474 sec maximalDeformation=0.4829 minLogLikelihood=2684443.1477 Total time spent: 0.6796 sec maximalDeformation=0.1848 minLogLikelihood=2684300.8057 Total time spent: 0.6832 sec maximalDeformation=0.2224 minLogLikelihood=2684211.6355 Total time spent: 1.3300 sec maximalDeformation=0.2199 minLogLikelihood=2683879.3437 Total time spent: 0.7116 sec maximalDeformation=0.2463 minLogLikelihood=2683723.6851 Total time spent: 1.3531 sec maximalDeformation=0.3751 minLogLikelihood=2683508.2309 Total time spent: 0.7192 sec maximalDeformation=0.0830 minLogLikelihood=2683360.4901 Total time spent: 0.7305 sec maximalDeformation=0.2406 minLogLikelihood=2682944.5237 Total time spent: 0.7172 sec maximalDeformation=0.1645 minLogLikelihood=2682790.7685 Total time spent: 0.7096 sec maximalDeformation=0.0784 minLogLikelihood=2682652.1028 Total time spent: 2.1439 sec maximalDeformation=0.0397 minLogLikelihood=2682643.8823 Total time spent: 2.6204 sec maximalDeformation=0.1620 minLogLikelihood=2682540.6258 Total time spent: 0.6663 sec maximalDeformation=0.0977 minLogLikelihood=2682417.4362 Total time spent: 0.6661 sec maximalDeformation=0.1015 minLogLikelihood=2682306.6881 Total time spent: 1.3587 sec maximalDeformation=0.0373 minLogLikelihood=2682286.9599 Total time spent: 1.7284 sec maximalDeformation=0.0000 minLogLikelihood=2682286.9599 Total time spent: 0.0000 sec maximalDeformationApplied: 1.4651 ======================================================= iterationNumber: 6 EM converged! maximalDeformation=0.2500 minLogLikelihood=2682158.5841 Total time spent: 2.6701 sec maximalDeformation=0.0426 minLogLikelihood=2682061.1829 Total time spent: 1.2132 sec maximalDeformation=0.2044 minLogLikelihood=2681784.4957 Total time spent: 0.9985 sec maximalDeformation=0.1302 minLogLikelihood=2681639.5268 Total time spent: 0.6265 sec maximalDeformation=0.1242 minLogLikelihood=2681563.2909 Total time spent: 0.6297 sec maximalDeformation=0.3737 minLogLikelihood=2681377.3428 Total time spent: 0.6382 sec maximalDeformation=0.3763 minLogLikelihood=2681074.6476 Total time spent: 0.6460 sec maximalDeformation=0.3437 minLogLikelihood=2680810.1843 Total time spent: 0.6442 sec maximalDeformation=0.3828 minLogLikelihood=2680693.4403 Total time spent: 0.6507 sec maximalDeformation=0.1171 minLogLikelihood=2680520.7575 Total time spent: 0.6675 sec maximalDeformation=0.1430 minLogLikelihood=2680270.9225 Total time spent: 0.6612 sec maximalDeformation=0.2741 minLogLikelihood=2679927.5655 Total time spent: 1.2629 sec maximalDeformation=0.2601 minLogLikelihood=2679613.3577 Total time spent: 0.6920 sec maximalDeformation=0.3041 minLogLikelihood=2679484.1130 Total time spent: 0.6773 sec maximalDeformation=0.1461 minLogLikelihood=2679448.9226 Total time spent: 1.2711 sec maximalDeformation=0.2922 minLogLikelihood=2679275.9790 Total time spent: 0.7007 sec maximalDeformation=0.0906 minLogLikelihood=2679146.7980 Total time spent: 0.6846 sec maximalDeformation=0.2505 minLogLikelihood=2678997.1161 Total time spent: 0.6704 sec maximalDeformation=0.1683 minLogLikelihood=2678645.7972 Total time spent: 0.7646 sec maximalDeformation=0.1367 minLogLikelihood=2678367.2971 Total time spent: 0.7661 sec maximalDeformation=0.0000 minLogLikelihood=2678367.2971 Total time spent: 0.0000 sec maximalDeformationApplied: 1.6836 ======================================================= iterationNumber: 7 EM converged! maximalDeformation=0.0566 minLogLikelihood=2678293.8937 Total time spent: 3.2670 sec maximalDeformation=0.1711 minLogLikelihood=2678103.2212 Total time spent: 1.2151 sec maximalDeformation=0.2173 minLogLikelihood=2677855.1126 Total time spent: 0.6200 sec maximalDeformation=0.3042 minLogLikelihood=2677595.4364 Total time spent: 1.2473 sec maximalDeformation=0.2349 minLogLikelihood=2677428.3438 Total time spent: 0.6431 sec maximalDeformation=0.1382 minLogLikelihood=2677337.0326 Total time spent: 0.6483 sec maximalDeformation=0.0975 minLogLikelihood=2677249.0278 Total time spent: 0.6582 sec maximalDeformation=0.3656 minLogLikelihood=2677145.3763 Total time spent: 0.6467 sec maximalDeformation=0.1526 minLogLikelihood=2677020.7197 Total time spent: 0.6531 sec maximalDeformation=0.0794 minLogLikelihood=2676921.4968 Total time spent: 0.6651 sec maximalDeformation=0.1773 minLogLikelihood=2676807.1744 Total time spent: 0.9074 sec maximalDeformation=0.1770 minLogLikelihood=2676646.3689 Total time spent: 0.6779 sec maximalDeformation=0.0891 minLogLikelihood=2676547.6801 Total time spent: 0.7476 sec maximalDeformation=0.0962 minLogLikelihood=2676392.8882 Total time spent: 0.7278 sec maximalDeformation=0.2617 minLogLikelihood=2676261.8116 Total time spent: 0.6823 sec maximalDeformation=0.2618 minLogLikelihood=2676159.0190 Total time spent: 0.6761 sec maximalDeformation=0.1595 minLogLikelihood=2676024.7765 Total time spent: 0.6767 sec maximalDeformation=0.0675 minLogLikelihood=2675905.2221 Total time spent: 0.6958 sec maximalDeformation=0.3955 minLogLikelihood=2675621.1906 Total time spent: 0.6727 sec maximalDeformation=0.2040 minLogLikelihood=2675410.1895 Total time spent: 1.3014 sec maximalDeformation=0.0000 minLogLikelihood=2675410.1895 Total time spent: 0.0000 sec maximalDeformationApplied: 1.3560 ======================================================= iterationNumber: 8 EM converged! maximalDeformation=0.1666 minLogLikelihood=2675265.4353 Total time spent: 3.2573 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0917 minLogLikelihood=2675190.6463 Total time spent: 0.6246 sec maximalDeformation=0.0760 minLogLikelihood=2675142.3205 Total time spent: 0.6383 sec maximalDeformation=0.1932 minLogLikelihood=2675068.2585 Total time spent: 0.6501 sec maximalDeformation=0.2060 minLogLikelihood=2674918.1092 Total time spent: 0.6699 sec maximalDeformation=0.1393 minLogLikelihood=2674819.0539 Total time spent: 1.2187 sec maximalDeformation=0.0260 minLogLikelihood=2674813.4678 Total time spent: 3.0118 sec maximalDeformation=0.1498 minLogLikelihood=2674794.5639 Total time spent: 0.6694 sec maximalDeformation=0.0261 minLogLikelihood=2674769.3010 Total time spent: 0.6736 sec maximalDeformation=0.1251 minLogLikelihood=2674659.1287 Total time spent: 0.6712 sec maximalDeformation=0.2567 minLogLikelihood=2674563.1387 Total time spent: 0.6896 sec maximalDeformation=0.2133 minLogLikelihood=2674519.9130 Total time spent: 0.7037 sec maximalDeformation=0.0972 minLogLikelihood=2674469.8194 Total time spent: 0.6869 sec maximalDeformation=0.1607 minLogLikelihood=2674388.1084 Total time spent: 0.7077 sec maximalDeformation=0.1869 minLogLikelihood=2674287.8105 Total time spent: 0.6964 sec maximalDeformation=0.2522 minLogLikelihood=2674184.2487 Total time spent: 0.6717 sec maximalDeformation=0.2554 minLogLikelihood=2674069.3011 Total time spent: 0.6750 sec maximalDeformation=0.1724 minLogLikelihood=2673981.7503 Total time spent: 0.6828 sec maximalDeformation=0.1681 minLogLikelihood=2673895.9459 Total time spent: 1.2848 sec maximalDeformation=0.2219 minLogLikelihood=2673763.9808 Total time spent: 0.6688 sec maximalDeformation=0.0000 minLogLikelihood=2673763.9808 Total time spent: 0.0000 sec maximalDeformationApplied: 1.5966 ======================================================= iterationNumber: 9 EM converged! maximalDeformation=0.2500 minLogLikelihood=2673723.6470 Total time spent: 2.8348 sec maximalDeformation=0.1498 minLogLikelihood=2673631.2283 Total time spent: 0.7782 sec maximalDeformation=0.1473 minLogLikelihood=2673571.8253 Total time spent: 0.7981 sec maximalDeformation=0.0769 minLogLikelihood=2673563.2101 Total time spent: 1.4430 sec maximalDeformation=0.0320 minLogLikelihood=2673547.8879 Total time spent: 0.6669 sec maximalDeformation=0.1082 minLogLikelihood=2673502.8859 Total time spent: 0.6512 sec maximalDeformation=0.1261 minLogLikelihood=2673434.4595 Total time spent: 0.6598 sec maximalDeformation=0.1982 minLogLikelihood=2673345.0243 Total time spent: 0.6492 sec maximalDeformation=0.1598 minLogLikelihood=2673259.4971 Total time spent: 0.6521 sec maximalDeformation=0.1889 minLogLikelihood=2673220.2056 Total time spent: 0.6610 sec maximalDeformation=0.0709 minLogLikelihood=2673181.1006 Total time spent: 0.6645 sec maximalDeformation=0.2191 minLogLikelihood=2673081.8519 Total time spent: 0.6942 sec maximalDeformation=0.1679 minLogLikelihood=2673007.6014 Total time spent: 0.6783 sec maximalDeformation=0.1913 minLogLikelihood=2672897.5519 Total time spent: 0.6782 sec maximalDeformation=0.2388 minLogLikelihood=2672802.9737 Total time spent: 0.8168 sec maximalDeformation=0.2685 minLogLikelihood=2672677.7873 Total time spent: 0.8220 sec maximalDeformation=0.2337 minLogLikelihood=2672541.7041 Total time spent: 0.8896 sec maximalDeformation=0.3419 minLogLikelihood=2672420.0124 Total time spent: 0.8867 sec maximalDeformation=0.1835 minLogLikelihood=2672261.1103 Total time spent: 0.9571 sec maximalDeformation=0.2099 minLogLikelihood=2672083.7126 Total time spent: 0.9448 sec maximalDeformation=0.0000 minLogLikelihood=2672083.7126 Total time spent: 0.0000 sec maximalDeformationApplied: 1.4051 ======================================================= iterationNumber: 10 EM converged! maximalDeformation=0.2500 minLogLikelihood=2671959.3092 Total time spent: 2.3152 sec maximalDeformation=0.1776 minLogLikelihood=2671896.6726 Total time spent: 0.6083 sec maximalDeformation=0.0920 minLogLikelihood=2671856.3997 Total time spent: 0.6139 sec maximalDeformation=0.0603 minLogLikelihood=2671818.5050 Total time spent: 0.6186 sec maximalDeformation=0.2524 minLogLikelihood=2671728.0937 Total time spent: 0.6225 sec maximalDeformation=0.2568 minLogLikelihood=2671666.6767 Total time spent: 0.6349 sec maximalDeformation=0.1259 minLogLikelihood=2671651.6098 Total time spent: 1.2363 sec maximalDeformation=0.1039 minLogLikelihood=2671594.7627 Total time spent: 0.6464 sec maximalDeformation=0.0909 minLogLikelihood=2671543.7460 Total time spent: 0.6544 sec maximalDeformation=0.2068 minLogLikelihood=2671481.4652 Total time spent: 0.6463 sec maximalDeformation=0.1679 minLogLikelihood=2671423.8630 Total time spent: 0.6559 sec maximalDeformation=0.1231 minLogLikelihood=2671377.1436 Total time spent: 0.6728 sec maximalDeformation=0.1191 minLogLikelihood=2671321.0737 Total time spent: 0.6829 sec maximalDeformation=0.1682 minLogLikelihood=2671271.4056 Total time spent: 0.6632 sec maximalDeformation=0.1202 minLogLikelihood=2671200.8759 Total time spent: 0.6634 sec maximalDeformation=0.1270 minLogLikelihood=2671129.6500 Total time spent: 0.6730 sec maximalDeformation=0.2993 minLogLikelihood=2671093.6286 Total time spent: 0.6695 sec maximalDeformation=0.1559 minLogLikelihood=2671050.5380 Total time spent: 0.6684 sec maximalDeformation=0.0915 minLogLikelihood=2670997.1119 Total time spent: 0.6854 sec maximalDeformation=0.0990 minLogLikelihood=2670935.6669 Total time spent: 0.6682 sec maximalDeformation=0.0000 minLogLikelihood=2670935.6669 Total time spent: 0.0000 sec maximalDeformationApplied: 1.2027 ======================================================= iterationNumber: 11 EM converged! maximalDeformation=0.1665 minLogLikelihood=2670890.9093 Total time spent: 2.9459 sec maximalDeformation=0.0663 minLogLikelihood=2670875.0591 Total time spent: 0.6227 sec maximalDeformation=0.0175 minLogLikelihood=2670864.6992 Total time spent: 0.6162 sec maximalDeformation=0.1202 minLogLikelihood=2670823.7765 Total time spent: 0.6222 sec maximalDeformation=0.1326 minLogLikelihood=2670799.8529 Total time spent: 0.6282 sec maximalDeformation=0.0541 minLogLikelihood=2670765.8983 Total time spent: 0.6357 sec maximalDeformation=0.0888 minLogLikelihood=2670729.2498 Total time spent: 0.6369 sec maximalDeformation=0.1174 minLogLikelihood=2670695.7838 Total time spent: 0.6405 sec maximalDeformation=0.2061 minLogLikelihood=2670652.5234 Total time spent: 0.6463 sec maximalDeformation=0.1775 minLogLikelihood=2670606.9287 Total time spent: 0.6517 sec maximalDeformation=0.1595 minLogLikelihood=2670566.2364 Total time spent: 0.6589 sec maximalDeformation=0.0872 minLogLikelihood=2670524.9267 Total time spent: 0.6624 sec maximalDeformation=0.1558 minLogLikelihood=2670517.5950 Total time spent: 1.7766 sec maximalDeformation=0.0691 minLogLikelihood=2670484.1910 Total time spent: 0.7061 sec maximalDeformation=0.1235 minLogLikelihood=2670449.5725 Total time spent: 0.7143 sec maximalDeformation=0.1132 minLogLikelihood=2670412.7554 Total time spent: 0.7186 sec maximalDeformation=0.1699 minLogLikelihood=2670357.2277 Total time spent: 0.7190 sec maximalDeformation=0.1553 minLogLikelihood=2670326.6761 Total time spent: 1.3737 sec maximalDeformation=0.0577 minLogLikelihood=2670302.1754 Total time spent: 0.7594 sec maximalDeformation=0.0462 minLogLikelihood=2670275.1554 Total time spent: 0.7193 sec maximalDeformation=0.0000 minLogLikelihood=2670275.1554 Total time spent: 0.0000 sec maximalDeformationApplied: 1.2035 ======================================================= iterationNumber: 12 EM converged! maximalDeformation=0.0753 minLogLikelihood=2670241.0727 Total time spent: 5.1060 sec maximalDeformation=0.0456 minLogLikelihood=2670220.5315 Total time spent: 0.9115 sec maximalDeformation=0.1042 minLogLikelihood=2670195.8776 Total time spent: 0.8127 sec maximalDeformation=0.1350 minLogLikelihood=2670167.3342 Total time spent: 0.9576 sec maximalDeformation=0.1115 minLogLikelihood=2670142.9256 Total time spent: 0.8413 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Constructing image-to-world transform from header information (../results_samseg_long/5771302/base/mode01_average.mgz) Read image: ../results_samseg_long/5771302/base/mode01_average.mgz maximalDeformation=0.0818 minLogLikelihood=2670119.2190 Total time spent: 0.9020 sec maximalDeformation=0.0622 minLogLikelihood=2670097.7065 Total time spent: 0.9363 sec maximalDeformation=0.0848 minLogLikelihood=2670077.1325 Total time spent: 0.9648 sec maximalDeformation=0.0449 minLogLikelihood=2670055.0557 Total time spent: 1.0171 sec maximalDeformation=0.0674 minLogLikelihood=2670026.6340 Total time spent: 1.0276 sec maximalDeformation=0.0708 minLogLikelihood=2669998.6824 Total time spent: 0.9296 sec maximalDeformation=0.1575 minLogLikelihood=2669975.8250 Total time spent: 0.8996 sec maximalDeformation=0.1298 minLogLikelihood=2669948.7290 Total time spent: 0.8931 sec maximalDeformation=0.1224 minLogLikelihood=2669928.1891 Total time spent: 0.7548 sec maximalDeformation=0.0931 minLogLikelihood=2669905.5269 Total time spent: 0.7400 sec maximalDeformation=0.0815 minLogLikelihood=2669881.6790 Total time spent: 0.7217 sec maximalDeformation=0.1645 minLogLikelihood=2669847.4317 Total time spent: 0.7253 sec maximalDeformation=0.2128 minLogLikelihood=2669835.7268 Total time spent: 0.7216 sec maximalDeformation=0.0661 minLogLikelihood=2669794.9531 Total time spent: 0.7305 sec maximalDeformation=0.1824 minLogLikelihood=2669741.6449 Total time spent: 0.7276 sec maximalDeformation=0.0000 minLogLikelihood=2669741.6449 Total time spent: 0.0000 sec maximalDeformationApplied: 0.6809 ======================================================= iterationNumber: 13 EM converged! maximalDeformation=0.1793 minLogLikelihood=2669706.4567 Total time spent: 3.0586 sec maximalDeformation=0.1326 minLogLikelihood=2669687.2609 Total time spent: 0.6690 sec maximalDeformation=0.0916 minLogLikelihood=2669666.8095 Total time spent: 0.6744 sec maximalDeformation=0.1809 minLogLikelihood=2669636.2018 Total time spent: 0.6788 sec maximalDeformation=0.2052 minLogLikelihood=2669616.8997 Total time spent: 0.7029 sec maximalDeformation=0.1796 minLogLikelihood=2669590.8743 Total time spent: 0.7172 sec maximalDeformation=0.2876 minLogLikelihood=2669589.7018 Total time spent: 0.7079 sec maximalDeformation=0.1415 minLogLikelihood=2669572.9774 Total time spent: 0.7236 sec maximalDeformation=0.1111 minLogLikelihood=2669558.0371 Total time spent: 0.7436 sec maximalDeformation=0.0482 minLogLikelihood=2669543.2210 Total time spent: 0.7309 sec maximalDeformation=0.1535 minLogLikelihood=2669518.1086 Total time spent: 0.7291 sec maximalDeformation=0.1977 minLogLikelihood=2669500.8313 Total time spent: 0.7298 sec maximalDeformation=0.1147 minLogLikelihood=2669478.6624 Total time spent: 0.7376 sec maximalDeformation=0.1431 minLogLikelihood=2669455.8078 Total time spent: 0.7419 sec maximalDeformation=0.0569 minLogLikelihood=2669434.2556 Total time spent: 0.7564 sec maximalDeformation=0.0481 minLogLikelihood=2669413.1386 Total time spent: 0.7511 sec maximalDeformation=0.0746 minLogLikelihood=2669390.8546 Total time spent: 0.7328 sec maximalDeformation=0.1094 minLogLikelihood=2669365.6136 Total time spent: 0.7445 sec maximalDeformation=0.1416 minLogLikelihood=2669341.9470 Total time spent: 0.7447 sec maximalDeformation=0.0552 minLogLikelihood=2669314.3493 Total time spent: 0.7385 sec maximalDeformation=0.0000 minLogLikelihood=2669314.3493 Total time spent: 0.0000 sec maximalDeformationApplied: 1.0856 ======================================================= using default intracranial structures to compute sbtiv measure Unknown Unknown (100%) Skull (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Pallidum (100%) Right-Thalamus (50%) Left-Pallidum (100%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) WM-hypointensities (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) non-WM-hypointensities (100%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Soft Soft_Nonbrain_Tissue (100%) Unknown Unknown (100%) Skull (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Pallidum (100%) Right-Thalamus (50%) Left-Pallidum (100%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) WM-hypointensities (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) non-WM-hypointensities (100%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Soft Soft_Nonbrain_Tissue (100%) Unknown Unknown (100%) Skull (100%) GlobalWM Brain-Stem (100%) Left-Cerebellum-White-Matter (100%) Right-Cerebellum-White-Matter (100%) Right-Cerebral-White-Matter (100%) Left-Cerebral-White-Matter (100%) Optic-Chiasm (100%) Right-VentralDC (100%) Left-VentralDC (100%) Right-Pallidum (100%) Right-Thalamus (50%) Left-Pallidum (100%) Left-Thalamus (50%) GlobalGM Left-Cerebellum-Cortex (100%) Right-Cerebellum-Cortex (100%) Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Wrote mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Transforming points Transforming points 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Left-Cerebral-Cortex (100%) Right-Cerebral-Cortex (100%) Right-Amygdala (100%) Left-Amygdala (100%) Right-Hippocampus (100%) Left-Hippocampus (100%) Left-Accumbens-area (100%) Right-Accumbens-area (100%) WM-hypointensities (100%) Left-Caudate (100%) Right-Thalamus (50%) Right-Caudate (100%) Left-Thalamus (50%) non-WM-hypointensities (100%) GlobalCSF_messy CSF (100%) Fluid_Inside_Eyes (50%) Right-choroid-plexus (100%) Left-choroid-plexus (100%) Right-vessel (100%) Left-vessel (100%) GlobalCSF_clean 4th-Ventricle (100%) Fluid_Inside_Eyes (50%) Right-Inf-Lat-Vent (100%) Left-Inf-Lat-Vent (100%) 3rd-Ventricle (100%) Left-Lateral-Ventricle (100%) Right-Lateral-Ventricle (100%) 5th-Ventricle (100%) Putamen Left-Putamen (100%) Right-Putamen (100%) Soft Soft_Nonbrain_Tissue (100%) {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=1.0000 minLogLikelihood=3286381.2065 Total time spent: 2.1132 sec maximalDeformation=0.2019 minLogLikelihood=3283253.4532 Total time spent: 0.7019 sec maximalDeformation=0.3733 minLogLikelihood=3279857.0123 Total time spent: 0.6904 sec maximalDeformation=0.5581 minLogLikelihood=3278636.9440 Total time spent: 0.7425 sec maximalDeformation=0.3286 minLogLikelihood=3276557.6931 Total time spent: 0.7334 sec maximalDeformation=0.1863 minLogLikelihood=3275058.8683 Total time spent: 0.7098 sec maximalDeformation=0.1659 minLogLikelihood=3273798.4194 Total time spent: 0.7338 sec maximalDeformation=0.2617 minLogLikelihood=3272943.7691 Total time spent: 0.7229 sec maximalDeformation=0.2159 minLogLikelihood=3272207.5295 Total time spent: 0.7616 sec maximalDeformation=0.1485 minLogLikelihood=3271409.2548 Total time spent: 0.7613 sec maximalDeformation=0.2103 minLogLikelihood=3271085.4666 Total time spent: 0.7589 sec maximalDeformation=0.1746 minLogLikelihood=3270751.6503 Total time spent: 0.7550 sec maximalDeformation=0.0907 minLogLikelihood=3270439.1286 Total time spent: 0.7628 sec maximalDeformation=0.0663 minLogLikelihood=3270194.2360 Total time spent: 0.7546 sec maximalDeformation=0.0993 minLogLikelihood=3269706.4547 Total time spent: 0.7615 sec maximalDeformation=0.2289 minLogLikelihood=3269533.8178 Total time spent: 0.7668 sec maximalDeformation=0.0705 minLogLikelihood=3269088.3588 Total time spent: 0.7567 sec maximalDeformation=0.0768 minLogLikelihood=3268719.2439 Total time spent: 0.7484 sec maximalDeformation=0.0888 minLogLikelihood=3268421.7874 Total time spent: 0.7457 sec maximalDeformation=0.0999 minLogLikelihood=3268124.1107 Total time spent: 0.7524 sec maximalDeformation=0.0000 minLogLikelihood=3268124.1107 Total time spent: 0.0000 sec maximalDeformationApplied: 0.8789 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0910 minLogLikelihood=3062751.8853 Total time spent: 3.1138 sec maximalDeformation=0.0257 minLogLikelihood=3062622.7163 Total time spent: 0.6696 sec maximalDeformation=0.0764 minLogLikelihood=3062532.5937 Total time spent: 1.3299 sec maximalDeformation=0.0360 minLogLikelihood=3062454.1789 Total time spent: 0.7396 sec maximalDeformation=0.0556 minLogLikelihood=3062274.4309 Total time spent: 0.7285 sec maximalDeformation=0.1592 minLogLikelihood=3062191.2753 Total time spent: 0.6946 sec maximalDeformation=0.0603 minLogLikelihood=3062013.3114 Total time spent: 0.7070 sec maximalDeformation=0.0750 minLogLikelihood=3061869.8281 Total time spent: 0.7292 sec maximalDeformation=0.0378 minLogLikelihood=3061774.5506 Total time spent: 0.7130 sec maximalDeformation=0.0401 minLogLikelihood=3061656.3095 Total time spent: 0.7410 sec maximalDeformation=0.0756 minLogLikelihood=3061502.2384 Total time spent: 0.7198 sec maximalDeformation=0.0575 minLogLikelihood=3061397.8478 Total time spent: 0.7369 sec maximalDeformation=0.0266 minLogLikelihood=3061305.0314 Total time spent: 0.7404 sec maximalDeformation=0.0505 minLogLikelihood=3061185.9659 Total time spent: 0.7384 sec maximalDeformation=0.0457 minLogLikelihood=3061089.4538 Total time spent: 0.7426 sec maximalDeformation=0.0835 minLogLikelihood=3060994.6704 Total time spent: 0.7415 sec maximalDeformation=0.0446 minLogLikelihood=3060878.9409 Total time spent: 0.7383 sec maximalDeformation=0.0531 minLogLikelihood=3060765.1753 Total time spent: 0.7390 sec maximalDeformation=0.0922 minLogLikelihood=3060751.2409 Total time spent: 0.7430 sec maximalDeformation=0.0385 minLogLikelihood=3060657.9978 Total time spent: 0.7598 sec maximalDeformation=0.0000 minLogLikelihood=3060657.9978 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3454 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=0.0473 minLogLikelihood=3059999.4925 Total time spent: 3.7250 sec maximalDeformation=0.0476 minLogLikelihood=3059971.2429 Total time spent: 0.6680 sec maximalDeformation=0.0199 minLogLikelihood=3059945.5704 Total time spent: 0.6842 sec maximalDeformation=0.0199 minLogLikelihood=3059908.8773 Total time spent: 0.7073 sec maximalDeformation=0.0165 minLogLikelihood=3059878.9764 Total time spent: 0.6962 sec maximalDeformation=0.1094 minLogLikelihood=3059875.9197 Total time spent: 0.6757 sec maximalDeformation=0.0524 minLogLikelihood=3059804.5622 Total time spent: 0.6856 sec maximalDeformation=0.0748 minLogLikelihood=3059791.1519 Total time spent: 0.6849 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Transforming points Transforming points 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0187 minLogLikelihood=3059764.4572 Total time spent: 0.7006 sec maximalDeformation=0.0924 minLogLikelihood=3059754.0930 Total time spent: 0.7133 sec maximalDeformation=0.0514 minLogLikelihood=3059715.7889 Total time spent: 0.7193 sec maximalDeformation=0.0568 minLogLikelihood=3059698.1640 Total time spent: 0.7296 sec maximalDeformation=0.0307 minLogLikelihood=3059692.5414 Total time spent: 0.7543 sec maximalDeformation=0.0271 minLogLikelihood=3059676.9515 Total time spent: 0.7401 sec maximalDeformation=0.0287 minLogLikelihood=3059645.2102 Total time spent: 0.7478 sec maximalDeformation=0.0410 minLogLikelihood=3059623.8096 Total time spent: 0.7534 sec maximalDeformation=0.0251 minLogLikelihood=3059601.3398 Total time spent: 0.7487 sec maximalDeformation=0.0301 minLogLikelihood=3059576.1220 Total time spent: 0.7664 sec maximalDeformation=0.0377 minLogLikelihood=3059545.8257 Total time spent: 0.7428 sec maximalDeformation=0.0299 minLogLikelihood=3059514.0796 Total time spent: 0.7436 sec maximalDeformation=0.0000 minLogLikelihood=3059514.0796 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1299 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=0.0500 minLogLikelihood=3059161.1643 Total time spent: 3.1267 sec maximalDeformation=0.0293 minLogLikelihood=3059134.7204 Total time spent: 0.7561 sec maximalDeformation=0.0104 minLogLikelihood=3059125.4779 Total time spent: 0.7374 sec maximalDeformation=0.0153 minLogLikelihood=3059110.0889 Total time spent: 0.7451 sec maximalDeformation=0.0239 minLogLikelihood=3059091.6135 Total time spent: 0.7197 sec maximalDeformation=0.0249 minLogLikelihood=3059073.5874 Total time spent: 0.6927 sec maximalDeformation=0.0278 minLogLikelihood=3059063.9654 Total time spent: 0.6981 sec maximalDeformation=0.0168 minLogLikelihood=3059050.1539 Total time spent: 0.6959 sec maximalDeformation=0.0152 minLogLikelihood=3059037.8496 Total time spent: 0.7015 sec maximalDeformation=0.0369 minLogLikelihood=3059027.2628 Total time spent: 0.7288 sec maximalDeformation=0.0125 minLogLikelihood=3059011.8755 Total time spent: 0.7113 sec maximalDeformation=0.0439 minLogLikelihood=3058984.1160 Total time spent: 0.7046 sec maximalDeformation=0.0221 minLogLikelihood=3058978.8473 Total time spent: 1.3356 sec maximalDeformation=0.0055 minLogLikelihood=3058970.1578 Total time spent: 0.7080 sec maximalDeformation=0.0327 minLogLikelihood=3058946.2875 Total time spent: 0.7084 sec maximalDeformation=0.0249 minLogLikelihood=3058935.0282 Total time spent: 0.7060 sec maximalDeformation=0.0145 minLogLikelihood=3058921.3642 Total time spent: 0.7123 sec maximalDeformation=0.0181 minLogLikelihood=3058903.0982 Total time spent: 0.7192 sec maximalDeformation=0.0222 minLogLikelihood=3058878.9052 Total time spent: 0.7226 sec maximalDeformation=0.0225 minLogLikelihood=3058848.1546 Total time spent: 0.7417 sec maximalDeformation=0.0000 minLogLikelihood=3058848.1546 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1290 ======================================================= ================================= timepointNumber: 0 perVoxelCost: 0.9351507264837418 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=1.0000 minLogLikelihood=3422265.6182 Total time spent: 2.1234 sec maximalDeformation=0.1713 minLogLikelihood=3419603.9989 Total time spent: 0.6872 sec maximalDeformation=0.4349 minLogLikelihood=3416067.1414 Total time spent: 0.7037 sec maximalDeformation=0.3312 minLogLikelihood=3414167.8481 Total time spent: 0.7603 sec maximalDeformation=0.2395 minLogLikelihood=3412610.1236 Total time spent: 0.7423 sec maximalDeformation=0.1996 minLogLikelihood=3411640.6312 Total time spent: 0.7160 sec maximalDeformation=0.1318 minLogLikelihood=3410914.8454 Total time spent: 0.7379 sec maximalDeformation=0.1765 minLogLikelihood=3410545.3949 Total time spent: 0.7223 sec maximalDeformation=0.1070 minLogLikelihood=3409860.0896 Total time spent: 0.7280 sec maximalDeformation=0.0925 minLogLikelihood=3409368.1403 Total time spent: 0.7333 sec maximalDeformation=0.1916 minLogLikelihood=3408948.4250 Total time spent: 0.7430 sec maximalDeformation=0.3744 minLogLikelihood=3408848.1433 Total time spent: 0.7424 sec maximalDeformation=0.1082 minLogLikelihood=3408350.7943 Total time spent: 0.7644 sec maximalDeformation=0.1824 minLogLikelihood=3408024.1982 Total time spent: 0.7496 sec maximalDeformation=0.0523 minLogLikelihood=3407764.3612 Total time spent: 0.7703 sec maximalDeformation=0.1599 minLogLikelihood=3407427.5286 Total time spent: 0.7779 sec maximalDeformation=0.1014 minLogLikelihood=3407153.4386 Total time spent: 0.7727 sec maximalDeformation=0.0738 minLogLikelihood=3406915.0821 Total time spent: 0.7543 sec maximalDeformation=0.0477 minLogLikelihood=3406749.3223 Total time spent: 0.7522 sec maximalDeformation=0.1094 minLogLikelihood=3406494.1515 Total time spent: 0.7325 sec maximalDeformation=0.0000 minLogLikelihood=3406494.1515 Total time spent: 0.0000 sec maximalDeformationApplied: 0.7346 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0572 minLogLikelihood=3189600.1140 Total time spent: 3.8585 sec maximalDeformation=0.0486 minLogLikelihood=3189469.0081 Total time spent: 0.6751 sec maximalDeformation=0.0462 minLogLikelihood=3189390.6156 Total time spent: 0.6671 sec maximalDeformation=0.0823 minLogLikelihood=3189311.5063 Total time spent: 0.7188 sec maximalDeformation=0.0289 minLogLikelihood=3189205.2273 Total time spent: 0.7338 sec maximalDeformation=0.0463 minLogLikelihood=3189098.7927 Total time spent: 0.6850 sec maximalDeformation=0.0459 minLogLikelihood=3189033.5577 Total time spent: 0.7043 sec maximalDeformation=0.0439 minLogLikelihood=3188964.4568 Total time spent: 0.7111 sec maximalDeformation=0.0520 minLogLikelihood=3188875.5933 Total time spent: 0.7173 sec maximalDeformation=0.0413 minLogLikelihood=3188789.5324 Total time spent: 0.7426 sec maximalDeformation=0.0779 minLogLikelihood=3188696.2183 Total time spent: 0.7474 sec maximalDeformation=0.1130 minLogLikelihood=3188651.5868 Total time spent: 0.7574 sec maximalDeformation=0.0485 minLogLikelihood=3188575.6066 Total time spent: 0.7651 sec maximalDeformation=0.0932 minLogLikelihood=3188521.4380 Total time spent: 0.7700 sec maximalDeformation=0.0308 minLogLikelihood=3188456.9647 Total time spent: 0.7588 sec maximalDeformation=0.0496 minLogLikelihood=3188376.1313 Total time spent: 2.1112 sec maximalDeformation=0.0864 minLogLikelihood=3188343.5238 Total time spent: 0.7557 sec maximalDeformation=0.0292 minLogLikelihood=3188272.3549 Total time spent: 0.7634 sec maximalDeformation=0.0610 minLogLikelihood=3188186.2341 Total time spent: 0.7637 sec maximalDeformation=0.0483 minLogLikelihood=3188133.6072 Total time spent: 0.7517 sec maximalDeformation=0.0000 minLogLikelihood=3188133.6072 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2728 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=0.0573 minLogLikelihood=3187304.9348 Total time spent: 3.0648 sec maximalDeformation=0.0107 minLogLikelihood=3187290.6200 Total time spent: 0.6981 sec maximalDeformation=0.0291 minLogLikelihood=3187262.6749 Total time spent: 0.7089 sec maximalDeformation=0.0356 minLogLikelihood=3187241.7229 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Transforming points Transforming points 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Total time spent: 0.7690 sec maximalDeformation=0.0425 minLogLikelihood=3187228.6603 Total time spent: 1.4778 sec maximalDeformation=0.0249 minLogLikelihood=3187216.3076 Total time spent: 0.7511 sec maximalDeformation=0.0118 minLogLikelihood=3187202.0523 Total time spent: 0.7420 sec maximalDeformation=0.0406 minLogLikelihood=3187170.5519 Total time spent: 0.7584 sec maximalDeformation=0.0559 minLogLikelihood=3187165.5632 Total time spent: 0.7472 sec maximalDeformation=0.0176 minLogLikelihood=3187141.1840 Total time spent: 0.8149 sec maximalDeformation=0.0336 minLogLikelihood=3187109.9337 Total time spent: 0.8342 sec maximalDeformation=0.0259 minLogLikelihood=3187090.8287 Total time spent: 0.8258 sec maximalDeformation=0.0255 minLogLikelihood=3187064.1342 Total time spent: 0.7566 sec maximalDeformation=0.0496 minLogLikelihood=3187039.6757 Total time spent: 0.7527 sec maximalDeformation=0.0857 minLogLikelihood=3187015.0809 Total time spent: 0.7616 sec maximalDeformation=0.0240 minLogLikelihood=3186981.2741 Total time spent: 0.7732 sec maximalDeformation=0.0591 minLogLikelihood=3186958.4201 Total time spent: 0.7644 sec maximalDeformation=0.0298 minLogLikelihood=3186931.5495 Total time spent: 0.7601 sec maximalDeformation=0.0397 minLogLikelihood=3186901.4204 Total time spent: 0.7490 sec maximalDeformation=0.0433 minLogLikelihood=3186866.2899 Total time spent: 0.7483 sec maximalDeformation=0.0000 minLogLikelihood=3186866.2899 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1797 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=0.1000 minLogLikelihood=3186520.4060 Total time spent: 2.7863 sec maximalDeformation=0.0315 minLogLikelihood=3186496.3375 Total time spent: 0.6892 sec maximalDeformation=0.0331 minLogLikelihood=3186483.2172 Total time spent: 0.6915 sec maximalDeformation=0.0584 minLogLikelihood=3186470.9187 Total time spent: 0.7474 sec maximalDeformation=0.0377 minLogLikelihood=3186452.9317 Total time spent: 0.7397 sec maximalDeformation=0.0810 minLogLikelihood=3186428.7958 Total time spent: 0.7074 sec maximalDeformation=0.0609 minLogLikelihood=3186410.7993 Total time spent: 0.7099 sec maximalDeformation=0.0133 minLogLikelihood=3186400.9943 Total time spent: 0.7270 sec maximalDeformation=0.0190 minLogLikelihood=3186379.1043 Total time spent: 0.7311 sec maximalDeformation=0.0331 minLogLikelihood=3186367.6249 Total time spent: 0.7417 sec maximalDeformation=0.0271 minLogLikelihood=3186351.1365 Total time spent: 0.7308 sec maximalDeformation=0.0729 minLogLikelihood=3186335.9457 Total time spent: 0.7399 sec maximalDeformation=0.0402 minLogLikelihood=3186325.5153 Total time spent: 0.7281 sec maximalDeformation=0.0146 minLogLikelihood=3186318.1297 Total time spent: 0.7378 sec maximalDeformation=0.0185 minLogLikelihood=3186307.8229 Total time spent: 0.7275 sec maximalDeformation=0.0206 minLogLikelihood=3186288.7925 Total time spent: 0.7177 sec maximalDeformation=0.0391 minLogLikelihood=3186280.2048 Total time spent: 1.3635 sec maximalDeformation=0.0128 minLogLikelihood=3186274.9137 Total time spent: 0.7306 sec maximalDeformation=0.0106 minLogLikelihood=3186262.5702 Total time spent: 0.7236 sec maximalDeformation=0.0163 minLogLikelihood=3186260.1450 Total time spent: 1.3958 sec maximalDeformation=0.0000 minLogLikelihood=3186260.1450 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3009 ======================================================= ================================= timepointNumber: 1 perVoxelCost: 0.9637834770667109 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.5000 minLogLikelihood=3164659.1327 Total time spent: 2.2499 sec maximalDeformation=0.2558 minLogLikelihood=3161791.1444 Total time spent: 0.6827 sec maximalDeformation=0.2497 minLogLikelihood=3159268.9807 Total time spent: 0.6751 sec maximalDeformation=0.1781 minLogLikelihood=3158994.6584 Total time spent: 1.4056 sec maximalDeformation=0.0890 minLogLikelihood=3158235.5997 Total time spent: 0.7349 sec maximalDeformation=0.1737 minLogLikelihood=3156985.5547 Total time spent: 1.3676 sec maximalDeformation=0.1458 minLogLikelihood=3155803.3884 Total time spent: 0.6974 sec maximalDeformation=0.1534 minLogLikelihood=3154524.0152 Total time spent: 0.7250 sec maximalDeformation=0.3755 minLogLikelihood=3153663.4043 Total time spent: 0.7127 sec maximalDeformation=0.3443 minLogLikelihood=3152781.0051 Total time spent: 0.7246 sec maximalDeformation=0.1233 minLogLikelihood=3152044.2553 Total time spent: 0.7171 sec maximalDeformation=0.1244 minLogLikelihood=3151655.6997 Total time spent: 0.7322 sec maximalDeformation=0.1001 minLogLikelihood=3151228.7122 Total time spent: 0.7499 sec maximalDeformation=0.0585 minLogLikelihood=3150998.2083 Total time spent: 0.7389 sec maximalDeformation=0.1029 minLogLikelihood=3150701.5553 Total time spent: 0.7419 sec maximalDeformation=0.1467 minLogLikelihood=3150418.0292 Total time spent: 0.7358 sec maximalDeformation=0.0827 minLogLikelihood=3150128.9464 Total time spent: 0.7420 sec maximalDeformation=0.0678 minLogLikelihood=3149947.4786 Total time spent: 0.7620 sec maximalDeformation=0.0545 minLogLikelihood=3149788.1553 Total time spent: 0.7446 sec maximalDeformation=0.1170 minLogLikelihood=3149560.7505 Total time spent: 0.7229 sec maximalDeformation=0.0000 minLogLikelihood=3149560.7505 Total time spent: 0.0000 sec maximalDeformationApplied: 0.9806 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0873 minLogLikelihood=3031208.2387 Total time spent: 3.1645 sec maximalDeformation=0.0455 minLogLikelihood=3031111.6429 Total time spent: 0.6990 sec maximalDeformation=0.0304 minLogLikelihood=3031098.8440 Total time spent: 1.3654 sec maximalDeformation=0.0119 minLogLikelihood=3031058.5718 Total time spent: 0.7417 sec maximalDeformation=0.0507 minLogLikelihood=3030966.6817 Total time spent: 0.7246 sec maximalDeformation=0.0371 minLogLikelihood=3030905.2341 Total time spent: 0.7117 sec maximalDeformation=0.0316 minLogLikelihood=3030822.0143 Total time spent: 0.7207 sec maximalDeformation=0.0904 minLogLikelihood=3030722.2599 Total time spent: 0.7260 sec maximalDeformation=0.0546 minLogLikelihood=3030643.9486 Total time spent: 0.7411 sec maximalDeformation=0.0241 minLogLikelihood=3030590.5223 Total time spent: 0.7299 sec maximalDeformation=0.0491 minLogLikelihood=3030506.8853 Total time spent: 0.7499 sec maximalDeformation=0.0576 minLogLikelihood=3030438.7379 Total time spent: 0.7390 sec maximalDeformation=0.0539 minLogLikelihood=3030353.8065 Total time spent: 0.7381 sec maximalDeformation=0.1030 minLogLikelihood=3030294.4173 Total time spent: 0.7511 sec maximalDeformation=0.0387 minLogLikelihood=3030204.8553 Total time spent: 0.7489 sec maximalDeformation=0.0210 minLogLikelihood=3030192.9936 Total time spent: 1.4233 sec maximalDeformation=0.0112 minLogLikelihood=3030182.0037 Total time spent: 0.7522 sec maximalDeformation=0.0328 minLogLikelihood=3030169.6042 Total time spent: 1.3897 sec maximalDeformation=0.0354 minLogLikelihood=3030125.7129 Total time spent: 0.7251 sec maximalDeformation=0.1133 minLogLikelihood=3030038.5355 Total time spent: 0.7369 sec maximalDeformation=0.0000 minLogLikelihood=3030038.5355 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3419 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points positions.size(): 3 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Transforming points Transforming points L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Wrote mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 ======================================================= iterationNumber: 2 EM converged! maximalDeformation=0.0551 minLogLikelihood=3029530.2832 Total time spent: 2.9853 sec maximalDeformation=0.0193 minLogLikelihood=3029506.7650 Total time spent: 0.6712 sec maximalDeformation=0.0200 minLogLikelihood=3029481.3886 Total time spent: 0.6706 sec maximalDeformation=0.0238 minLogLikelihood=3029460.7336 Total time spent: 0.7383 sec maximalDeformation=0.0255 minLogLikelihood=3029431.3351 Total time spent: 0.7200 sec maximalDeformation=0.0623 minLogLikelihood=3029410.9079 Total time spent: 0.7082 sec maximalDeformation=0.0642 minLogLikelihood=3029399.9816 Total time spent: 0.7120 sec maximalDeformation=0.0226 minLogLikelihood=3029376.2768 Total time spent: 0.7178 sec maximalDeformation=0.0363 minLogLikelihood=3029353.8449 Total time spent: 0.7206 sec maximalDeformation=0.0162 minLogLikelihood=3029350.7893 Total time spent: 2.3703 sec maximalDeformation=0.0092 minLogLikelihood=3029342.9067 Total time spent: 0.7341 sec maximalDeformation=0.0459 minLogLikelihood=3029318.3009 Total time spent: 0.7440 sec maximalDeformation=0.0881 minLogLikelihood=3029299.8050 Total time spent: 0.7474 sec maximalDeformation=0.0473 minLogLikelihood=3029262.8097 Total time spent: 0.7422 sec maximalDeformation=0.0204 minLogLikelihood=3029238.1108 Total time spent: 0.7481 sec maximalDeformation=0.0167 minLogLikelihood=3029209.7222 Total time spent: 0.7524 sec maximalDeformation=0.0717 minLogLikelihood=3029188.9228 Total time spent: 0.7363 sec maximalDeformation=0.0234 minLogLikelihood=3029161.2969 Total time spent: 0.7387 sec maximalDeformation=0.0407 minLogLikelihood=3029126.5978 Total time spent: 0.7544 sec maximalDeformation=0.0249 minLogLikelihood=3029094.5725 Total time spent: 0.7311 sec maximalDeformation=0.0000 minLogLikelihood=3029094.5725 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1444 ======================================================= iterationNumber: 3 EM converged! maximalDeformation=0.0470 minLogLikelihood=3028881.5986 Total time spent: 3.3928 sec maximalDeformation=0.0307 minLogLikelihood=3028858.4195 Total time spent: 0.6786 sec maximalDeformation=0.0108 minLogLikelihood=3028849.1856 Total time spent: 0.6762 sec maximalDeformation=0.0129 minLogLikelihood=3028836.8677 Total time spent: 0.7213 sec maximalDeformation=0.0177 minLogLikelihood=3028821.1592 Total time spent: 0.7094 sec maximalDeformation=0.0268 minLogLikelihood=3028804.3159 Total time spent: 0.6951 sec maximalDeformation=0.0372 minLogLikelihood=3028792.5985 Total time spent: 0.6972 sec maximalDeformation=0.0100 minLogLikelihood=3028781.2434 Total time spent: 0.7065 sec maximalDeformation=0.0162 minLogLikelihood=3028768.7560 Total time spent: 0.7125 sec maximalDeformation=0.0220 minLogLikelihood=3028760.0177 Total time spent: 0.7239 sec maximalDeformation=0.0191 minLogLikelihood=3028747.6356 Total time spent: 0.7259 sec maximalDeformation=0.0266 minLogLikelihood=3028731.8528 Total time spent: 0.7332 sec maximalDeformation=0.0247 minLogLikelihood=3028725.4511 Total time spent: 0.7255 sec maximalDeformation=0.0081 minLogLikelihood=3028717.4923 Total time spent: 0.7218 sec maximalDeformation=0.0208 minLogLikelihood=3028702.5614 Total time spent: 0.7200 sec maximalDeformation=0.0098 minLogLikelihood=3028692.8951 Total time spent: 0.7183 sec maximalDeformation=0.0499 minLogLikelihood=3028668.6709 Total time spent: 0.7121 sec maximalDeformation=0.0271 minLogLikelihood=3028652.3593 Total time spent: 1.3640 sec maximalDeformation=0.0100 minLogLikelihood=3028633.9828 Total time spent: 0.7452 sec maximalDeformation=0.0368 minLogLikelihood=3028590.7904 Total time spent: 0.7370 sec maximalDeformation=0.0000 minLogLikelihood=3028590.7904 Total time spent: 0.0000 sec maximalDeformationApplied: 0.0928 ======================================================= ================================= timepointNumber: 2 perVoxelCost: 0.9244265786565617 ================================= **************************************************************************************************** iterationNumber: 0 totalCost: 13014501.511651058 latentAtlasCost: 214538.47968437636 totalTimepointCost: 12799963.03196668 **************************************************************************************************** maximalDeformation=0.1284 minLogLikelihood=254006.4241 maximalDeformation=0.2370 minLogLikelihood=252990.7683 maximalDeformation=0.1291 minLogLikelihood=251356.1206 maximalDeformation=0.0750 minLogLikelihood=250348.8401 maximalDeformation=0.0329 minLogLikelihood=249451.0728 maximalDeformation=0.0589 minLogLikelihood=247981.0433 maximalDeformation=0.0845 minLogLikelihood=247378.8163 maximalDeformation=0.0676 minLogLikelihood=246632.1741 maximalDeformation=0.0398 minLogLikelihood=246080.8809 maximalDeformation=0.0325 minLogLikelihood=245484.0581 maximalDeformation=0.0705 minLogLikelihood=245045.6032 maximalDeformation=0.0651 minLogLikelihood=244482.6078 maximalDeformation=0.0137 minLogLikelihood=244229.2005 maximalDeformation=0.0257 minLogLikelihood=243918.9807 maximalDeformation=0.0384 minLogLikelihood=243603.4818 maximalDeformation=0.0494 minLogLikelihood=243332.4198 maximalDeformation=0.0211 minLogLikelihood=243163.6683 maximalDeformation=0.0133 minLogLikelihood=243010.4679 maximalDeformation=0.0240 minLogLikelihood=242884.1090 maximalDeformation=0.0272 minLogLikelihood=242730.6923 maximalDeformation=0.0000 minLogLikelihood=242730.6923 {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1171 minLogLikelihood=3032184.2599 Total time spent: 3.4544 sec maximalDeformation=0.2219 minLogLikelihood=3031691.7288 Total time spent: 0.6584 sec maximalDeformation=0.0867 minLogLikelihood=3031273.6948 Total time spent: 0.6595 sec maximalDeformation=0.0659 minLogLikelihood=3030832.3021 Total time spent: 0.7100 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0421 minLogLikelihood=3030462.5699 Total time spent: 0.7323 sec maximalDeformation=0.1661 minLogLikelihood=3030105.8198 Total time spent: 0.6908 sec maximalDeformation=0.1572 minLogLikelihood=3029940.5057 Total time spent: 0.6875 sec maximalDeformation=0.0790 minLogLikelihood=3029669.2808 Total time spent: 0.7027 sec maximalDeformation=0.0565 minLogLikelihood=3029523.4501 Total time spent: 0.7069 sec maximalDeformation=0.0376 minLogLikelihood=3029489.7558 Total time spent: 1.3879 sec maximalDeformation=0.0256 minLogLikelihood=3029437.0885 Total time spent: 0.7216 sec maximalDeformation=0.0275 minLogLikelihood=3029334.2286 Total time spent: 0.7488 sec maximalDeformation=0.0639 minLogLikelihood=3029274.6955 Total time spent: 0.7294 sec maximalDeformation=0.0407 minLogLikelihood=3029153.4095 Total time spent: 0.7241 sec maximalDeformation=0.0390 minLogLikelihood=3029066.8527 Total time spent: 0.7320 sec maximalDeformation=0.0243 minLogLikelihood=3029013.9995 Total time spent: 0.7153 sec maximalDeformation=0.0427 minLogLikelihood=3028941.0670 Total time spent: 0.7193 sec maximalDeformation=0.0799 minLogLikelihood=3028907.6312 Total time spent: 0.7210 sec maximalDeformation=0.0222 minLogLikelihood=3028867.8178 Total time spent: 0.7175 sec maximalDeformation=0.0359 minLogLikelihood=3028836.7386 Total time spent: 0.7275 sec maximalDeformation=0.0000 minLogLikelihood=3028836.7386 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3259 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0521 minLogLikelihood=3028570.9468 Total time spent: 3.4258 sec maximalDeformation=0.0746 minLogLikelihood=3028550.3772 Total time spent: 1.3140 sec maximalDeformation=0.0314 minLogLikelihood=3028534.7942 Total time spent: 0.6752 sec maximalDeformation=0.0309 minLogLikelihood=3028523.0687 Total time spent: 0.7342 sec maximalDeformation=0.0289 minLogLikelihood=3028513.5354 Total time spent: 0.7584 sec maximalDeformation=0.0158 minLogLikelihood=3028498.6023 Total time spent: 0.7038 sec maximalDeformation=0.0275 minLogLikelihood=3028478.1487 Total time spent: 0.6955 sec maximalDeformation=0.0168 minLogLikelihood=3028463.1170 Total time spent: 0.7115 sec maximalDeformation=0.0199 minLogLikelihood=3028447.9823 Total time spent: 0.7098 sec maximalDeformation=0.0331 minLogLikelihood=3028428.4076 Total time spent: 0.7094 sec maximalDeformation=0.0409 minLogLikelihood=3028414.0232 Total time spent: 0.7116 sec maximalDeformation=0.0145 minLogLikelihood=3028402.1636 Total time spent: 0.7210 sec maximalDeformation=0.0192 minLogLikelihood=3028390.6491 Total time spent: 0.7329 sec maximalDeformation=0.0196 minLogLikelihood=3028380.1822 Total time spent: 0.7254 sec maximalDeformation=0.0353 minLogLikelihood=3028370.6902 Total time spent: 0.7310 sec maximalDeformation=0.0349 minLogLikelihood=3028361.2932 Total time spent: 0.7183 sec maximalDeformation=0.0493 minLogLikelihood=3028359.4716 Total time spent: 0.7273 sec maximalDeformation=0.0231 minLogLikelihood=3028350.4220 Total time spent: 0.7224 sec maximalDeformation=0.0163 minLogLikelihood=3028345.2120 Total time spent: 0.7254 sec maximalDeformation=0.0209 minLogLikelihood=3028338.1439 Total time spent: 0.7205 sec maximalDeformation=0.0000 minLogLikelihood=3028338.1439 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1480 ======================================================= ================================= timepointNumber: 0 perVoxelCost: 0.9196466379381438 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1250 minLogLikelihood=3159454.3816 Total time spent: 2.5898 sec maximalDeformation=0.2117 minLogLikelihood=3158985.5922 Total time spent: 0.7233 sec maximalDeformation=0.0369 minLogLikelihood=3158649.2624 Total time spent: 0.7521 sec maximalDeformation=0.0972 minLogLikelihood=3157998.5655 Total time spent: 0.7771 sec maximalDeformation=0.0741 minLogLikelihood=3157661.6701 Total time spent: 0.8030 sec maximalDeformation=0.0910 minLogLikelihood=3157373.9898 Total time spent: 0.7991 sec maximalDeformation=0.1086 minLogLikelihood=3157167.9887 Total time spent: 0.8241 sec maximalDeformation=0.0488 minLogLikelihood=3156984.9553 Total time spent: 0.8209 sec maximalDeformation=0.0879 minLogLikelihood=3156773.8672 Total time spent: 0.7715 sec maximalDeformation=0.0670 minLogLikelihood=3156589.7339 Total time spent: 0.8096 sec maximalDeformation=0.0544 minLogLikelihood=3156488.2182 Total time spent: 0.7916 sec maximalDeformation=0.0287 minLogLikelihood=3156410.7799 Total time spent: 0.7752 sec maximalDeformation=0.0522 minLogLikelihood=3156344.8865 Total time spent: 0.8659 sec maximalDeformation=0.0409 minLogLikelihood=3156293.2807 Total time spent: 0.7660 sec maximalDeformation=0.0479 minLogLikelihood=3156225.8093 Total time spent: 0.7914 sec maximalDeformation=0.0619 minLogLikelihood=3156185.6008 Total time spent: 0.7850 sec maximalDeformation=0.0260 minLogLikelihood=3156147.0248 Total time spent: 0.7193 sec maximalDeformation=0.0241 minLogLikelihood=3156123.5648 Total time spent: 0.7020 sec maximalDeformation=0.0331 minLogLikelihood=3156097.6662 Total time spent: 1.3251 sec maximalDeformation=0.0280 minLogLikelihood=3156068.0431 Total time spent: 0.7197 sec maximalDeformation=0.0000 minLogLikelihood=3156068.0431 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2952 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0312 minLogLikelihood=3155815.3265 Total time spent: 2.7893 sec maximalDeformation=0.0186 minLogLikelihood=3155802.8508 Total time spent: 0.6540 sec maximalDeformation=0.0077 minLogLikelihood=3155796.1417 Total time spent: 0.6580 sec maximalDeformation=0.0141 minLogLikelihood=3155787.0198 Total time spent: 0.7376 sec maximalDeformation=0.0346 minLogLikelihood=3155785.0547 Total time spent: 0.7547 sec maximalDeformation=0.0632 minLogLikelihood=3155782.2345 Total time spent: 0.6904 sec maximalDeformation=0.0248 minLogLikelihood=3155760.1373 Total time spent: 0.6886 sec maximalDeformation=0.0163 minLogLikelihood=3155748.9456 Total time spent: 0.6971 sec maximalDeformation=0.0176 minLogLikelihood=3155738.7141 Total time spent: 0.7130 sec maximalDeformation=0.0454 minLogLikelihood=3155726.5374 Total time spent: 0.7064 sec maximalDeformation=0.0488 minLogLikelihood=3155706.2742 Total time spent: 0.7206 sec maximalDeformation=0.0326 minLogLikelihood=3155689.6376 Total time spent: 0.7243 sec maximalDeformation=0.0201 minLogLikelihood=3155674.2134 Total time spent: 0.7401 sec maximalDeformation=0.0205 minLogLikelihood=3155658.3768 Total time spent: 0.7244 sec maximalDeformation=0.0472 minLogLikelihood=3155643.0918 Total time spent: 0.7325 sec maximalDeformation=0.0400 minLogLikelihood=3155634.1470 Total time spent: 0.7483 sec maximalDeformation=0.0408 minLogLikelihood=3155616.6091 Total time spent: 0.7256 sec maximalDeformation=0.0300 minLogLikelihood=3155604.5794 Total time spent: 0.7162 sec maximalDeformation=0.0258 minLogLikelihood=3155592.5358 Total time spent: 0.7060 sec maximalDeformation=0.0661 minLogLikelihood=3155591.2004 Total time spent: 0.7089 sec maximalDeformation=0.0000 minLogLikelihood=3155591.2004 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1986 ======================================================= Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_01.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points positions.size(): 3 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Transforming points Transforming points L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Wrote mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz ================================= timepointNumber: 1 perVoxelCost: 0.9478050912558391 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1745 minLogLikelihood=3005528.8116 Total time spent: 3.1970 sec maximalDeformation=0.1178 minLogLikelihood=3004905.7080 Total time spent: 0.7501 sec maximalDeformation=0.1368 minLogLikelihood=3004534.6146 Total time spent: 0.7487 sec maximalDeformation=0.0565 minLogLikelihood=3004125.8588 Total time spent: 0.7743 sec maximalDeformation=0.0519 minLogLikelihood=3003794.3825 Total time spent: 0.7934 sec maximalDeformation=0.1363 minLogLikelihood=3003450.9056 Total time spent: 0.7798 sec maximalDeformation=0.1073 minLogLikelihood=3003296.0070 Total time spent: 0.7321 sec maximalDeformation=0.0730 minLogLikelihood=3003039.5087 Total time spent: 0.7621 sec maximalDeformation=0.0305 minLogLikelihood=3002914.3142 Total time spent: 0.7962 sec maximalDeformation=0.0369 minLogLikelihood=3002791.1903 Total time spent: 0.7726 sec maximalDeformation=0.0409 minLogLikelihood=3002656.0984 Total time spent: 0.7741 sec maximalDeformation=0.1315 minLogLikelihood=3002571.1014 Total time spent: 0.8145 sec maximalDeformation=0.1131 minLogLikelihood=3002533.6309 Total time spent: 0.8096 sec maximalDeformation=0.0294 minLogLikelihood=3002464.1357 Total time spent: 0.8221 sec maximalDeformation=0.0348 minLogLikelihood=3002405.5182 Total time spent: 0.7767 sec maximalDeformation=0.0521 minLogLikelihood=3002335.9177 Total time spent: 0.7601 sec maximalDeformation=0.1223 minLogLikelihood=3002314.0227 Total time spent: 0.7575 sec maximalDeformation=0.0423 minLogLikelihood=3002261.3106 Total time spent: 0.7752 sec maximalDeformation=0.0374 minLogLikelihood=3002226.5137 Total time spent: 0.7927 sec maximalDeformation=0.0267 minLogLikelihood=3002220.7430 Total time spent: 1.4359 sec maximalDeformation=0.0000 minLogLikelihood=3002220.7430 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2851 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0253 minLogLikelihood=3002045.3087 Total time spent: 3.8032 sec maximalDeformation=0.0187 minLogLikelihood=3002038.3826 Total time spent: 0.7657 sec maximalDeformation=0.0076 minLogLikelihood=3002032.0917 Total time spent: 0.8275 sec maximalDeformation=0.0203 minLogLikelihood=3002016.3336 Total time spent: 0.8244 sec maximalDeformation=0.0295 minLogLikelihood=3002000.8294 Total time spent: 0.8193 sec maximalDeformation=0.1001 minLogLikelihood=3001984.5241 Total time spent: 0.7782 sec maximalDeformation=0.0422 minLogLikelihood=3001974.4910 Total time spent: 0.8495 sec maximalDeformation=0.0236 minLogLikelihood=3001946.3485 Total time spent: 0.7806 sec maximalDeformation=0.0231 minLogLikelihood=3001932.4310 Total time spent: 0.8126 sec maximalDeformation=0.0158 minLogLikelihood=3001921.7537 Total time spent: 0.8312 sec maximalDeformation=0.0810 minLogLikelihood=3001915.8630 Total time spent: 0.8151 sec maximalDeformation=0.0273 minLogLikelihood=3001889.9718 Total time spent: 0.8034 sec maximalDeformation=0.0373 minLogLikelihood=3001878.4998 Total time spent: 0.8319 sec maximalDeformation=0.0093 minLogLikelihood=3001869.5703 Total time spent: 0.7801 sec maximalDeformation=0.0336 minLogLikelihood=3001858.5030 Total time spent: 0.8001 sec maximalDeformation=0.0130 minLogLikelihood=3001847.5071 Total time spent: 0.7195 sec maximalDeformation=0.0265 minLogLikelihood=3001832.7257 Total time spent: 0.7120 sec maximalDeformation=0.0105 minLogLikelihood=3001831.0882 Total time spent: 1.3515 sec maximalDeformation=0.0059 minLogLikelihood=3001829.2238 Total time spent: 0.7254 sec maximalDeformation=0.0293 minLogLikelihood=3001823.0807 Total time spent: 0.7183 sec maximalDeformation=0.0000 minLogLikelihood=3001823.0807 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2210 ======================================================= ================================= timepointNumber: 2 perVoxelCost: 0.9125111608658311 ================================= **************************************************************************************************** iterationNumber: 1 totalCost: 12828767.880109316 latentAtlasCost: 225553.14140015282 totalTimepointCost: 12603214.738709163 **************************************************************************************************** maximalDeformation=0.1228 minLogLikelihood=260730.8553 maximalDeformation=0.2523 minLogLikelihood=259957.1665 maximalDeformation=0.0971 minLogLikelihood=258978.6100 maximalDeformation=0.0594 minLogLikelihood=258231.9479 maximalDeformation=0.0327 minLogLikelihood=257402.6057 maximalDeformation=0.0389 minLogLikelihood=256416.9400 maximalDeformation=0.0777 minLogLikelihood=255824.5618 maximalDeformation=0.1120 minLogLikelihood=255036.5900 maximalDeformation=0.0273 minLogLikelihood=254726.8209 maximalDeformation=0.0186 minLogLikelihood=254422.0756 maximalDeformation=0.0367 minLogLikelihood=254034.7786 maximalDeformation=0.0914 minLogLikelihood=253841.0793 maximalDeformation=0.0643 minLogLikelihood=253548.5587 maximalDeformation=0.0130 minLogLikelihood=253432.1067 maximalDeformation=0.0216 minLogLikelihood=253227.5014 maximalDeformation=0.0496 minLogLikelihood=253098.0175 maximalDeformation=0.0396 minLogLikelihood=252873.9725 maximalDeformation=0.0120 minLogLikelihood=252787.2992 maximalDeformation=0.0157 minLogLikelihood=252693.0551 maximalDeformation=0.0231 minLogLikelihood=252576.2184 maximalDeformation=0.0000 minLogLikelihood=252576.2184 {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ==================== Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1402 minLogLikelihood=3017155.5770 Total time spent: 2.7468 sec maximalDeformation=0.1529 minLogLikelihood=3016675.9999 Total time spent: 0.6379 sec maximalDeformation=0.0276 minLogLikelihood=3016472.8876 Total time spent: 0.6404 sec maximalDeformation=0.0508 minLogLikelihood=3016055.2094 Total time spent: 0.6975 sec maximalDeformation=0.0758 minLogLikelihood=3015741.2000 Total time spent: 0.7253 sec maximalDeformation=0.1784 minLogLikelihood=3015507.8453 Total time spent: 0.6725 sec maximalDeformation=0.1441 minLogLikelihood=3015346.6090 Total time spent: 0.6751 sec maximalDeformation=0.0569 minLogLikelihood=3015181.5179 Total time spent: 0.6760 sec maximalDeformation=0.0678 minLogLikelihood=3015073.9617 Total time spent: 0.6747 sec maximalDeformation=0.0529 minLogLikelihood=3014978.8365 Total time spent: 0.6873 sec maximalDeformation=0.0539 minLogLikelihood=3014897.5747 Total time spent: 0.6882 sec maximalDeformation=0.0636 minLogLikelihood=3014822.1778 Total time spent: 0.8035 sec maximalDeformation=0.0322 minLogLikelihood=3014806.5964 Total time spent: 1.3626 sec maximalDeformation=0.0235 minLogLikelihood=3014785.5575 Total time spent: 0.6939 sec maximalDeformation=0.0478 minLogLikelihood=3014736.2135 Total time spent: 0.6981 sec maximalDeformation=0.0521 minLogLikelihood=3014690.5939 Total time spent: 0.6957 sec maximalDeformation=0.0429 minLogLikelihood=3014658.9429 Total time spent: 0.7031 sec maximalDeformation=0.0328 minLogLikelihood=3014628.1313 Total time spent: 0.6950 sec maximalDeformation=0.0700 minLogLikelihood=3014599.5964 Total time spent: 0.7008 sec maximalDeformation=0.0170 minLogLikelihood=3014576.8748 Total time spent: 0.7041 sec maximalDeformation=0.0000 minLogLikelihood=3014576.8748 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2362 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0176 minLogLikelihood=3014296.6816 Total time spent: 3.8390 sec maximalDeformation=0.0126 minLogLikelihood=3014289.4117 Total time spent: 0.6580 sec maximalDeformation=0.0273 minLogLikelihood=3014278.0198 Total time spent: 0.6633 sec maximalDeformation=0.0252 minLogLikelihood=3014273.4721 Total time spent: 0.7369 sec maximalDeformation=0.0143 minLogLikelihood=3014265.3840 Total time spent: 0.7588 sec maximalDeformation=0.0109 minLogLikelihood=3014258.3961 Total time spent: 0.6989 sec maximalDeformation=0.0120 minLogLikelihood=3014251.7603 Total time spent: 0.6819 sec maximalDeformation=0.0208 minLogLikelihood=3014242.4633 Total time spent: 0.7070 sec maximalDeformation=0.0241 minLogLikelihood=3014229.5976 Total time spent: 0.6937 sec maximalDeformation=0.0141 minLogLikelihood=3014220.2311 Total time spent: 0.7112 sec maximalDeformation=0.0113 minLogLikelihood=3014211.5643 Total time spent: 0.7026 sec maximalDeformation=0.0108 minLogLikelihood=3014205.0779 Total time spent: 0.7102 sec maximalDeformation=0.0321 minLogLikelihood=3014200.2068 Total time spent: 0.7127 sec maximalDeformation=0.0172 minLogLikelihood=3014191.3567 Total time spent: 0.7085 sec maximalDeformation=0.0090 minLogLikelihood=3014187.3739 Total time spent: 0.7162 sec maximalDeformation=0.0207 minLogLikelihood=3014180.5781 Total time spent: 0.7164 sec maximalDeformation=0.0160 minLogLikelihood=3014172.6004 Total time spent: 0.7064 sec maximalDeformation=0.0306 minLogLikelihood=3014165.2384 Total time spent: 0.7083 sec maximalDeformation=0.0127 minLogLikelihood=3014158.0156 Total time spent: 0.7076 sec maximalDeformation=0.0088 minLogLikelihood=3014154.0606 Total time spent: 0.7084 sec maximalDeformation=0.0000 minLogLikelihood=3014154.0606 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1177 ======================================================= ================================= timepointNumber: 0 perVoxelCost: 0.9155161314542616 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1088 minLogLikelihood=3144807.9884 Total time spent: 2.9632 sec maximalDeformation=0.1064 minLogLikelihood=3144317.9670 Total time spent: 0.6479 sec maximalDeformation=0.0359 minLogLikelihood=3143984.8380 Total time spent: 0.6499 sec maximalDeformation=0.1742 minLogLikelihood=3143647.6202 Total time spent: 0.7030 sec maximalDeformation=0.0616 minLogLikelihood=3143374.3491 Total time spent: 0.7353 sec maximalDeformation=0.0499 minLogLikelihood=3143182.3371 Total time spent: 0.6891 sec maximalDeformation=0.0409 minLogLikelihood=3143037.3727 Total time spent: 0.6854 sec maximalDeformation=0.0435 minLogLikelihood=3142831.9765 Total time spent: 0.6870 sec maximalDeformation=0.0653 minLogLikelihood=3142716.4615 Total time spent: 0.7015 sec maximalDeformation=0.0311 minLogLikelihood=3142626.9839 Total time spent: 0.6991 sec maximalDeformation=0.0378 minLogLikelihood=3142566.4255 Total time spent: 0.7174 sec maximalDeformation=0.0242 minLogLikelihood=3142512.2268 Total time spent: 0.7326 sec maximalDeformation=0.0346 minLogLikelihood=3142443.7759 Total time spent: 0.7171 sec maximalDeformation=0.0790 minLogLikelihood=3142419.4830 Total time spent: 0.7249 sec maximalDeformation=0.0435 minLogLikelihood=3142367.4899 Total time spent: 0.7175 sec maximalDeformation=0.0097 minLogLikelihood=3142349.0660 Total time spent: 0.7180 sec maximalDeformation=0.0591 minLogLikelihood=3142329.2708 Total time spent: 0.7232 sec maximalDeformation=0.0228 minLogLikelihood=3142324.9084 Total time spent: 1.4914 sec maximalDeformation=0.0157 minLogLikelihood=3142304.5012 Total time spent: 0.7922 sec maximalDeformation=0.0196 minLogLikelihood=3142285.1803 Total time spent: 0.8321 sec maximalDeformation=0.0000 minLogLikelihood=3142285.1803 Total time spent: 0.0000 sec maximalDeformationApplied: 0.3148 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0156 minLogLikelihood=3142074.0223 Total time spent: 3.4333 sec maximalDeformation=0.0102 minLogLikelihood=3142065.1931 Total time spent: 0.6626 sec maximalDeformation=0.0426 minLogLikelihood=3142063.9225 Total time spent: 0.6713 sec maximalDeformation=0.0172 minLogLikelihood=3142051.5030 Total time spent: 0.7329 sec maximalDeformation=0.0148 minLogLikelihood=3142037.8967 Total time spent: 0.7613 sec maximalDeformation=0.0421 minLogLikelihood=3142037.4856 Total time spent: 0.7102 sec maximalDeformation=0.0234 minLogLikelihood=3142021.8172 Total time spent: 0.6930 sec maximalDeformation=0.0155 minLogLikelihood=3142013.5826 Total time spent: 0.7151 sec maximalDeformation=0.0216 minLogLikelihood=3142005.0590 Total time spent: 0.7047 sec maximalDeformation=0.0478 minLogLikelihood=3141991.8259 Total time spent: 0.7066 sec maximalDeformation=0.0404 minLogLikelihood=3141982.8274 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_02.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points positions.size(): 3 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Transforming points Transforming points L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Wrote mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Total time spent: 0.7154 sec maximalDeformation=0.0136 minLogLikelihood=3141972.6018 Total time spent: 0.7289 sec maximalDeformation=0.0317 minLogLikelihood=3141960.3731 Total time spent: 0.7242 sec maximalDeformation=0.0173 minLogLikelihood=3141952.4475 Total time spent: 0.7247 sec maximalDeformation=0.0280 minLogLikelihood=3141945.7197 Total time spent: 0.7240 sec maximalDeformation=0.0192 minLogLikelihood=3141937.1393 Total time spent: 0.7337 sec maximalDeformation=0.0105 minLogLikelihood=3141929.7280 Total time spent: 0.7254 sec maximalDeformation=0.0220 minLogLikelihood=3141920.3895 Total time spent: 0.7304 sec maximalDeformation=0.0281 minLogLikelihood=3141917.3215 Total time spent: 1.3663 sec maximalDeformation=0.0073 minLogLikelihood=3141910.5907 Total time spent: 0.7316 sec maximalDeformation=0.0000 minLogLikelihood=3141910.5907 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1599 ======================================================= ================================= timepointNumber: 1 perVoxelCost: 0.9436441319192193 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1250 minLogLikelihood=2992963.8706 Total time spent: 2.6711 sec maximalDeformation=0.1391 minLogLikelihood=2992541.3648 Total time spent: 0.7705 sec maximalDeformation=0.0439 minLogLikelihood=2992365.6855 Total time spent: 0.7422 sec maximalDeformation=0.0640 minLogLikelihood=2991988.2272 Total time spent: 0.8333 sec maximalDeformation=0.0501 minLogLikelihood=2991658.7769 Total time spent: 0.8141 sec maximalDeformation=0.2553 minLogLikelihood=2991463.9107 Total time spent: 0.8080 sec maximalDeformation=0.0722 minLogLikelihood=2991215.4130 Total time spent: 0.7929 sec maximalDeformation=0.0849 minLogLikelihood=2991040.1524 Total time spent: 0.7822 sec maximalDeformation=0.0550 minLogLikelihood=2990907.4665 Total time spent: 0.8318 sec maximalDeformation=0.0592 minLogLikelihood=2990759.5918 Total time spent: 0.8103 sec maximalDeformation=0.0776 minLogLikelihood=2990699.2078 Total time spent: 1.5402 sec maximalDeformation=0.0350 minLogLikelihood=2990627.6454 Total time spent: 0.8152 sec maximalDeformation=0.0776 minLogLikelihood=2990561.3181 Total time spent: 0.8160 sec maximalDeformation=0.0486 minLogLikelihood=2990514.0402 Total time spent: 0.8282 sec maximalDeformation=0.0135 minLogLikelihood=2990475.3539 Total time spent: 0.8637 sec maximalDeformation=0.0467 minLogLikelihood=2990437.2089 Total time spent: 0.8411 sec maximalDeformation=0.0419 minLogLikelihood=2990404.8801 Total time spent: 0.8372 sec maximalDeformation=0.0292 minLogLikelihood=2990376.1547 Total time spent: 0.8041 sec maximalDeformation=0.0319 minLogLikelihood=2990356.5343 Total time spent: 0.8024 sec maximalDeformation=0.0417 minLogLikelihood=2990333.1659 Total time spent: 0.7289 sec maximalDeformation=0.0000 minLogLikelihood=2990333.1659 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2354 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0162 minLogLikelihood=2990197.5324 Total time spent: 3.6170 sec maximalDeformation=0.0091 minLogLikelihood=2990190.4779 Total time spent: 0.6770 sec maximalDeformation=0.0137 minLogLikelihood=2990184.0113 Total time spent: 0.6811 sec maximalDeformation=0.0108 minLogLikelihood=2990178.2380 Total time spent: 0.7447 sec maximalDeformation=0.0140 minLogLikelihood=2990167.8185 Total time spent: 0.7686 sec maximalDeformation=0.0186 minLogLikelihood=2990159.9227 Total time spent: 0.7094 sec maximalDeformation=0.0099 minLogLikelihood=2990151.4470 Total time spent: 0.7008 sec maximalDeformation=0.0131 minLogLikelihood=2990144.8718 Total time spent: 0.6981 sec maximalDeformation=0.0103 minLogLikelihood=2990137.5238 Total time spent: 0.7088 sec maximalDeformation=0.0193 minLogLikelihood=2990124.4947 Total time spent: 0.7104 sec maximalDeformation=0.0405 minLogLikelihood=2990114.7841 Total time spent: 0.7261 sec maximalDeformation=0.0147 minLogLikelihood=2990101.4785 Total time spent: 0.7189 sec maximalDeformation=0.0236 minLogLikelihood=2990090.0609 Total time spent: 0.7373 sec maximalDeformation=0.0213 minLogLikelihood=2990082.5587 Total time spent: 0.7585 sec maximalDeformation=0.0099 minLogLikelihood=2990076.8793 Total time spent: 0.8199 sec maximalDeformation=0.0374 minLogLikelihood=2990066.2954 Total time spent: 0.7942 sec maximalDeformation=0.0243 minLogLikelihood=2990059.4396 Total time spent: 0.7389 sec maximalDeformation=0.0343 minLogLikelihood=2990051.0366 Total time spent: 0.7459 sec maximalDeformation=0.0239 minLogLikelihood=2990045.5046 Total time spent: 0.7370 sec maximalDeformation=0.0098 minLogLikelihood=2990040.0147 Total time spent: 0.7734 sec maximalDeformation=0.0000 minLogLikelihood=2990040.0147 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1572 ======================================================= ================================= timepointNumber: 2 perVoxelCost: 0.9096458187890553 ================================= **************************************************************************************************** iterationNumber: 2 totalCost: 12788070.688006334 latentAtlasCost: 235436.3531690004 totalTimepointCost: 12552634.334837334 **************************************************************************************************** maximalDeformation=0.1090 minLogLikelihood=267383.9588 maximalDeformation=0.0587 minLogLikelihood=266045.4461 maximalDeformation=0.0546 minLogLikelihood=265327.8650 maximalDeformation=0.0299 minLogLikelihood=264747.3662 maximalDeformation=0.0466 minLogLikelihood=264100.4177 maximalDeformation=0.0980 minLogLikelihood=263855.4941 maximalDeformation=0.0560 minLogLikelihood=263527.2361 maximalDeformation=0.0213 minLogLikelihood=263324.3791 maximalDeformation=0.0171 minLogLikelihood=263069.4915 maximalDeformation=0.0320 minLogLikelihood=262723.7401 maximalDeformation=0.0613 minLogLikelihood=262669.7348 maximalDeformation=0.0431 minLogLikelihood=262342.8322 maximalDeformation=0.0116 minLogLikelihood=262253.3445 maximalDeformation=0.0196 minLogLikelihood=262098.8644 maximalDeformation=0.0344 minLogLikelihood=261927.3481 maximalDeformation=0.0521 minLogLikelihood=261788.4853 maximalDeformation=0.0133 minLogLikelihood=261699.6201 maximalDeformation=0.0111 minLogLikelihood=261614.5613 maximalDeformation=0.0170 minLogLikelihood=261546.6144 maximalDeformation=0.0258 minLogLikelihood=261456.7454 maximalDeformation=0.0000 minLogLikelihood=261456.7454 {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.0808 minLogLikelihood=3005930.4109 Total time spent: 3.2775 sec maximalDeformation=0.1354 minLogLikelihood=3005697.9238 Total time spent: 0.6684 sec maximalDeformation=0.0647 minLogLikelihood=3005433.9772 Total time spent: 0.6728 sec maximalDeformation=0.0420 minLogLikelihood=3005224.2619 Total time spent: 0.7322 sec maximalDeformation=0.0395 minLogLikelihood=3005026.5762 Total time spent: 0.7578 sec maximalDeformation=0.1006 minLogLikelihood=3004854.5991 Total time spent: 0.7032 sec maximalDeformation=0.0950 minLogLikelihood=3004719.9398 Total time spent: 0.6948 sec maximalDeformation=0.0250 minLogLikelihood=3004639.5536 Total time spent: 0.7066 sec maximalDeformation=0.0399 minLogLikelihood=3004544.8432 Total time spent: 0.7122 sec maximalDeformation=0.0446 minLogLikelihood=3004431.7825 Total time spent: 0.7104 sec maximalDeformation=0.1403 minLogLikelihood=3004417.6253 Total time spent: 0.7144 sec maximalDeformation=0.0570 minLogLikelihood=3004314.6783 Total time spent: 0.7234 sec maximalDeformation=0.0444 minLogLikelihood=3004266.2686 Total time spent: 0.7188 sec maximalDeformation=0.0126 minLogLikelihood=3004237.9649 Total time spent: 0.7190 sec maximalDeformation=0.0399 minLogLikelihood=3004184.8455 Total time spent: 0.7166 sec maximalDeformation=0.0496 minLogLikelihood=3004157.7447 Total time spent: 0.7171 sec maximalDeformation=0.0415 minLogLikelihood=3004131.6911 Total time spent: 0.7231 sec maximalDeformation=0.0105 minLogLikelihood=3004119.2290 Total time spent: 0.7072 sec maximalDeformation=0.0184 minLogLikelihood=3004102.8487 Total time spent: 0.7067 sec maximalDeformation=0.0395 minLogLikelihood=3004089.6417 Total time spent: 0.7187 sec maximalDeformation=0.0000 minLogLikelihood=3004089.6417 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2184 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0237 minLogLikelihood=3003919.0562 Total time spent: 3.5099 sec maximalDeformation=0.0041 minLogLikelihood=3003915.9719 Total time spent: 0.6807 sec maximalDeformation=0.0278 minLogLikelihood=3003906.4424 Total time spent: 0.6933 sec maximalDeformation=0.0181 minLogLikelihood=3003902.3834 Total time spent: 0.7567 sec maximalDeformation=0.0151 minLogLikelihood=3003897.9365 Total time spent: 0.7875 sec maximalDeformation=0.0146 minLogLikelihood=3003893.7719 Total time spent: 0.7061 sec maximalDeformation=0.0196 minLogLikelihood=3003888.2830 Total time spent: 0.6969 sec maximalDeformation=0.0252 minLogLikelihood=3003881.8354 Total time spent: 0.7158 sec maximalDeformation=0.0082 minLogLikelihood=3003875.7478 Total time spent: 0.7108 sec maximalDeformation=0.0151 minLogLikelihood=3003868.8103 Total time spent: 0.7194 sec maximalDeformation=0.0117 minLogLikelihood=3003863.6784 Total time spent: 0.7309 sec maximalDeformation=0.0177 minLogLikelihood=3003857.0774 Total time spent: 0.7310 sec maximalDeformation=0.0168 minLogLikelihood=3003851.1686 Total time spent: 0.7400 sec maximalDeformation=0.0107 minLogLikelihood=3003846.4634 Total time spent: 0.7322 sec maximalDeformation=0.0092 minLogLikelihood=3003840.7023 Total time spent: 0.7299 sec maximalDeformation=0.0162 minLogLikelihood=3003837.7804 Total time spent: 1.3754 sec maximalDeformation=0.0063 minLogLikelihood=3003833.5954 Total time spent: 0.7284 sec maximalDeformation=0.0067 minLogLikelihood=3003829.4973 Total time spent: 0.7081 sec maximalDeformation=0.0092 minLogLikelihood=3003825.9443 Total time spent: 0.7116 sec maximalDeformation=0.0096 minLogLikelihood=3003823.0418 Total time spent: 0.7077 sec maximalDeformation=0.0000 minLogLikelihood=3003823.0418 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1140 ======================================================= ================================= timepointNumber: 0 perVoxelCost: 0.9130384449261266 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.0983 minLogLikelihood=3134399.6035 Total time spent: 2.7999 sec maximalDeformation=0.1704 minLogLikelihood=3134189.1048 Total time spent: 0.6519 sec maximalDeformation=0.0695 minLogLikelihood=3133891.9873 Total time spent: 0.6677 sec maximalDeformation=0.1102 minLogLikelihood=3133710.5553 Total time spent: 0.7241 sec maximalDeformation=0.0337 minLogLikelihood=3133543.0071 Total time spent: 0.7729 sec maximalDeformation=0.0976 minLogLikelihood=3133320.4288 Total time spent: 0.7027 sec maximalDeformation=0.0613 minLogLikelihood=3133186.5798 Total time spent: 0.6996 sec maximalDeformation=0.0520 minLogLikelihood=3133055.0156 Total time spent: 0.6905 sec maximalDeformation=0.0445 minLogLikelihood=3132973.9714 Total time spent: 0.7115 sec maximalDeformation=0.0453 minLogLikelihood=3132889.4683 Total time spent: 0.7238 sec maximalDeformation=0.0398 minLogLikelihood=3132801.3983 Total time spent: 0.7279 sec maximalDeformation=0.0440 minLogLikelihood=3132747.6563 Total time spent: 0.7313 sec maximalDeformation=0.0310 minLogLikelihood=3132680.7958 Total time spent: 1.3725 sec maximalDeformation=0.0287 minLogLikelihood=3132651.9850 Total time spent: 0.7172 sec maximalDeformation=0.0164 minLogLikelihood=3132619.2324 Total time spent: 0.7222 sec maximalDeformation=0.0239 minLogLikelihood=3132590.6344 Total time spent: 0.7233 sec maximalDeformation=0.0556 minLogLikelihood=3132583.6350 Total time spent: 0.7234 sec maximalDeformation=0.0168 minLogLikelihood=3132558.9613 Total time spent: 0.7195 sec maximalDeformation=0.0187 minLogLikelihood=3132539.3973 Total time spent: 0.7193 sec maximalDeformation=0.0650 minLogLikelihood=3132525.8651 Total time spent: 0.7235 sec maximalDeformation=0.0000 minLogLikelihood=3132525.8651 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_03.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points positions.size(): 3 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Transforming points Transforming points L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2091 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0321 minLogLikelihood=3132424.0446 Total time spent: 2.8069 sec maximalDeformation=0.0177 minLogLikelihood=3132414.5202 Total time spent: 0.6369 sec maximalDeformation=0.0057 minLogLikelihood=3132411.8762 Total time spent: 0.6489 sec maximalDeformation=0.0072 minLogLikelihood=3132408.5099 Total time spent: 0.7139 sec maximalDeformation=0.0099 minLogLikelihood=3132403.8680 Total time spent: 0.7515 sec maximalDeformation=0.0165 minLogLikelihood=3132396.3269 Total time spent: 0.6894 sec maximalDeformation=0.0175 minLogLikelihood=3132386.7280 Total time spent: 0.6879 sec maximalDeformation=0.0218 minLogLikelihood=3132375.7230 Total time spent: 0.6895 sec maximalDeformation=0.0248 minLogLikelihood=3132369.0708 Total time spent: 0.6997 sec maximalDeformation=0.0176 minLogLikelihood=3132364.0910 Total time spent: 0.7018 sec maximalDeformation=0.0103 minLogLikelihood=3132358.0580 Total time spent: 0.7094 sec maximalDeformation=0.0063 minLogLikelihood=3132353.5527 Total time spent: 0.7103 sec maximalDeformation=0.0262 minLogLikelihood=3132348.2052 Total time spent: 0.7246 sec maximalDeformation=0.0142 minLogLikelihood=3132340.1064 Total time spent: 0.7186 sec maximalDeformation=0.0163 minLogLikelihood=3132332.9713 Total time spent: 0.7331 sec maximalDeformation=0.0107 minLogLikelihood=3132327.8643 Total time spent: 0.7273 sec maximalDeformation=0.0505 minLogLikelihood=3132322.0120 Total time spent: 0.7426 sec maximalDeformation=0.0207 minLogLikelihood=3132312.7979 Total time spent: 0.7357 sec maximalDeformation=0.0380 minLogLikelihood=3132307.6003 Total time spent: 0.7365 sec maximalDeformation=0.0085 minLogLikelihood=3132304.1143 Total time spent: 0.7368 sec maximalDeformation=0.0000 minLogLikelihood=3132304.1143 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1429 ======================================================= ================================= timepointNumber: 1 perVoxelCost: 0.9412812542629714 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.0937 minLogLikelihood=2983344.1723 Total time spent: 2.7679 sec maximalDeformation=0.1377 minLogLikelihood=2983113.1092 Total time spent: 0.6489 sec maximalDeformation=0.0610 minLogLikelihood=2982837.5616 Total time spent: 0.6599 sec maximalDeformation=0.0523 minLogLikelihood=2982631.8266 Total time spent: 0.7134 sec maximalDeformation=0.0528 minLogLikelihood=2982428.5199 Total time spent: 0.7346 sec maximalDeformation=0.1762 minLogLikelihood=2982405.6870 Total time spent: 0.6968 sec maximalDeformation=0.0573 minLogLikelihood=2982154.2345 Total time spent: 0.6853 sec maximalDeformation=0.1274 minLogLikelihood=2982040.3858 Total time spent: 0.6923 sec maximalDeformation=0.0402 minLogLikelihood=2981945.5103 Total time spent: 0.6858 sec maximalDeformation=0.0949 minLogLikelihood=2981809.8618 Total time spent: 0.6961 sec maximalDeformation=0.1217 minLogLikelihood=2981774.9914 Total time spent: 0.7043 sec maximalDeformation=0.0360 minLogLikelihood=2981699.2110 Total time spent: 0.7228 sec maximalDeformation=0.0483 minLogLikelihood=2981638.3537 Total time spent: 0.6989 sec maximalDeformation=0.0692 minLogLikelihood=2981598.3955 Total time spent: 0.6941 sec maximalDeformation=0.0900 minLogLikelihood=2981551.2427 Total time spent: 0.6885 sec maximalDeformation=0.0366 minLogLikelihood=2981496.6098 Total time spent: 0.6925 sec maximalDeformation=0.0436 minLogLikelihood=2981474.4403 Total time spent: 1.3039 sec maximalDeformation=0.0375 minLogLikelihood=2981457.1333 Total time spent: 0.6824 sec maximalDeformation=0.0305 minLogLikelihood=2981444.7350 Total time spent: 0.6971 sec maximalDeformation=0.0277 minLogLikelihood=2981416.6566 Total time spent: 0.6861 sec maximalDeformation=0.0000 minLogLikelihood=2981416.6566 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2169 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0126 minLogLikelihood=2981352.0460 Total time spent: 3.4769 sec maximalDeformation=0.0072 minLogLikelihood=2981347.7517 Total time spent: 0.6485 sec maximalDeformation=0.0236 minLogLikelihood=2981337.6357 Total time spent: 0.6576 sec maximalDeformation=0.0162 minLogLikelihood=2981331.4197 Total time spent: 0.7257 sec maximalDeformation=0.0062 minLogLikelihood=2981323.6589 Total time spent: 0.7596 sec maximalDeformation=0.0192 minLogLikelihood=2981311.5264 Total time spent: 0.6924 sec maximalDeformation=0.0132 minLogLikelihood=2981308.2015 Total time spent: 1.3377 sec maximalDeformation=0.0029 minLogLikelihood=2981306.1015 Total time spent: 0.7039 sec maximalDeformation=0.0095 minLogLikelihood=2981297.9815 Total time spent: 0.7006 sec maximalDeformation=0.0097 minLogLikelihood=2981290.6470 Total time spent: 0.7052 sec maximalDeformation=0.0320 minLogLikelihood=2981283.2769 Total time spent: 0.6973 sec maximalDeformation=0.0300 minLogLikelihood=2981266.5185 Total time spent: 1.3095 sec maximalDeformation=0.0171 minLogLikelihood=2981254.7729 Total time spent: 0.6885 sec maximalDeformation=0.0167 minLogLikelihood=2981244.9930 Total time spent: 0.6870 sec maximalDeformation=0.0102 minLogLikelihood=2981239.5985 Total time spent: 0.6898 sec maximalDeformation=0.0124 minLogLikelihood=2981233.9320 Total time spent: 0.6994 sec maximalDeformation=0.0191 minLogLikelihood=2981224.8967 Total time spent: 0.7149 sec maximalDeformation=0.0464 minLogLikelihood=2981221.4821 Total time spent: 0.7013 sec maximalDeformation=0.0106 minLogLikelihood=2981213.7476 Total time spent: 0.7102 sec maximalDeformation=0.0135 minLogLikelihood=2981207.8772 Total time spent: 0.7197 sec maximalDeformation=0.0000 minLogLikelihood=2981207.8772 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1324 ======================================================= ================================= timepointNumber: 2 perVoxelCost: 0.9077429974365383 ================================= **************************************************************************************************** iterationNumber: 3 totalCost: 12766667.888658557 latentAtlasCost: 244605.30580084148 totalTimepointCost: 12522062.582857715 **************************************************************************************************** maximalDeformation=0.1000 minLogLikelihood=274691.0309 maximalDeformation=0.1659 minLogLikelihood=274261.0693 maximalDeformation=0.0968 minLogLikelihood=273428.9038 maximalDeformation=0.0424 minLogLikelihood=273058.0874 maximalDeformation=0.0229 minLogLikelihood=272633.1804 maximalDeformation=0.0343 minLogLikelihood=272129.9492 maximalDeformation=0.0875 minLogLikelihood=271875.3176 maximalDeformation=0.0560 minLogLikelihood=271544.3320 maximalDeformation=0.0325 minLogLikelihood=271374.8886 maximalDeformation=0.0120 minLogLikelihood=271200.0404 maximalDeformation=0.0475 minLogLikelihood=271008.4573 maximalDeformation=0.0444 minLogLikelihood=270780.5059 maximalDeformation=0.0121 minLogLikelihood=270689.0544 maximalDeformation=0.0218 minLogLikelihood=270532.9476 maximalDeformation=0.0304 minLogLikelihood=270361.3562 maximalDeformation=0.0286 minLogLikelihood=270296.6648 maximalDeformation=0.0271 minLogLikelihood=270172.9707 maximalDeformation=0.0142 minLogLikelihood=270099.9272 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Wrote mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 maximalDeformation=0.0234 minLogLikelihood=270007.2392 maximalDeformation=0.0445 minLogLikelihood=269982.0248 maximalDeformation=0.0000 minLogLikelihood=269982.0248 {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} {'maximumNumberOfDeformationIterations': 20, 'absoluteCostPerVoxelDecreaseStopCriterion': 0.0001, 'verbose': False, 'maximalDeformationStopCriterion': 0.001, 'lineSearchMaximalDeformationIntervalStopCriterion': 0.001, 'maximalDeformationAppliedStopCriterion': 0.0, 'BFGSMaximumMemoryLength': 12, 'multiResolutionSpecification': [{'atlasFileName': '../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz', 'targetDownsampledVoxelSpacing': 1.0, 'maximumNumberOfIterations': 100, 'estimateBiasField': True}]} ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1300 minLogLikelihood=2997668.9764 Total time spent: 2.9390 sec maximalDeformation=0.0623 minLogLikelihood=2997323.9006 Total time spent: 0.6459 sec maximalDeformation=0.0522 minLogLikelihood=2997038.0434 Total time spent: 0.6578 sec maximalDeformation=0.0465 minLogLikelihood=2996836.8026 Total time spent: 0.7162 sec maximalDeformation=0.1201 minLogLikelihood=2996642.6668 Total time spent: 0.7347 sec maximalDeformation=0.0608 minLogLikelihood=2996448.8180 Total time spent: 0.6801 sec maximalDeformation=0.0548 minLogLikelihood=2996338.1271 Total time spent: 0.6742 sec maximalDeformation=0.0245 minLogLikelihood=2996267.8876 Total time spent: 0.6761 sec maximalDeformation=0.0347 minLogLikelihood=2996161.1048 Total time spent: 0.6845 sec maximalDeformation=0.0807 minLogLikelihood=2996118.3008 Total time spent: 0.6834 sec maximalDeformation=0.0408 minLogLikelihood=2996072.3118 Total time spent: 0.7043 sec maximalDeformation=0.0131 minLogLikelihood=2996048.8297 Total time spent: 0.6855 sec maximalDeformation=0.0275 minLogLikelihood=2996012.2830 Total time spent: 0.6963 sec maximalDeformation=0.0843 minLogLikelihood=2995984.9717 Total time spent: 0.6961 sec maximalDeformation=0.0250 minLogLikelihood=2995950.8261 Total time spent: 0.6967 sec maximalDeformation=0.0475 minLogLikelihood=2995934.5839 Total time spent: 0.6939 sec maximalDeformation=0.0268 minLogLikelihood=2995918.6441 Total time spent: 0.7014 sec maximalDeformation=0.0073 minLogLikelihood=2995907.8124 Total time spent: 0.6971 sec maximalDeformation=0.0217 minLogLikelihood=2995892.6112 Total time spent: 0.7052 sec maximalDeformation=0.0273 minLogLikelihood=2995882.6517 Total time spent: 0.7040 sec maximalDeformation=0.0000 minLogLikelihood=2995882.6517 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1867 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0250 minLogLikelihood=2995669.9648 Total time spent: 2.9096 sec maximalDeformation=0.0133 minLogLikelihood=2995665.1508 Total time spent: 0.6717 sec maximalDeformation=0.0057 minLogLikelihood=2995662.6714 Total time spent: 0.6713 sec maximalDeformation=0.0113 minLogLikelihood=2995659.3340 Total time spent: 0.7380 sec maximalDeformation=0.0107 minLogLikelihood=2995655.3895 Total time spent: 0.7560 sec maximalDeformation=0.0160 minLogLikelihood=2995648.8606 Total time spent: 0.7063 sec maximalDeformation=0.0166 minLogLikelihood=2995642.9429 Total time spent: 0.6842 sec maximalDeformation=0.0166 minLogLikelihood=2995636.8438 Total time spent: 0.6811 sec maximalDeformation=0.0127 minLogLikelihood=2995633.7526 Total time spent: 0.6993 sec maximalDeformation=0.0118 minLogLikelihood=2995628.7338 Total time spent: 0.6985 sec maximalDeformation=0.0215 minLogLikelihood=2995623.4372 Total time spent: 0.7111 sec maximalDeformation=0.0087 minLogLikelihood=2995618.8297 Total time spent: 0.7431 sec maximalDeformation=0.0132 minLogLikelihood=2995614.7817 Total time spent: 0.7315 sec maximalDeformation=0.0174 minLogLikelihood=2995610.5666 Total time spent: 0.7149 sec maximalDeformation=0.0262 minLogLikelihood=2995606.7027 Total time spent: 0.7166 sec maximalDeformation=0.0094 minLogLikelihood=2995603.0539 Total time spent: 0.7270 sec maximalDeformation=0.0084 minLogLikelihood=2995600.2760 Total time spent: 0.7444 sec maximalDeformation=0.0093 minLogLikelihood=2995597.3583 Total time spent: 0.7201 sec maximalDeformation=0.0169 minLogLikelihood=2995595.0447 Total time spent: 0.7162 sec maximalDeformation=0.0072 minLogLikelihood=2995591.9281 Total time spent: 0.7230 sec maximalDeformation=0.0000 minLogLikelihood=2995591.9281 Total time spent: 0.0000 sec maximalDeformationApplied: 0.0748 ======================================================= ================================= timepointNumber: 0 perVoxelCost: 0.9111268575827688 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1312 minLogLikelihood=3126641.8177 Total time spent: 3.4124 sec maximalDeformation=0.0515 minLogLikelihood=3126316.7361 Total time spent: 0.7322 sec maximalDeformation=0.0809 minLogLikelihood=3125999.3612 Total time spent: 0.7391 sec maximalDeformation=0.1419 minLogLikelihood=3125856.2021 Total time spent: 0.7457 sec maximalDeformation=0.0270 minLogLikelihood=3125619.9625 Total time spent: 0.7965 sec maximalDeformation=0.1169 minLogLikelihood=3125421.4412 Total time spent: 0.7830 sec maximalDeformation=0.0530 minLogLikelihood=3125306.9779 Total time spent: 0.7821 sec maximalDeformation=0.0456 minLogLikelihood=3125183.3581 Total time spent: 0.7777 sec maximalDeformation=0.0380 minLogLikelihood=3125105.8921 Total time spent: 0.7638 sec maximalDeformation=0.0388 minLogLikelihood=3125035.9597 Total time spent: 0.7729 sec maximalDeformation=0.0778 minLogLikelihood=3124991.1921 Total time spent: 0.7940 sec maximalDeformation=0.0430 minLogLikelihood=3124947.8206 Total time spent: 0.7750 sec maximalDeformation=0.0340 minLogLikelihood=3124912.4305 Total time spent: 0.8084 sec 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz Transforming points Transforming points Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_04.mgz Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 1 0.398942 SLIDING L-BFGS BFGS-MaximumMemoryLength: 12 LineSearchMaximalDeformationIntervalStopCriterion: 0.001 MaximalDeformationStopCriterion: 0.001 MaximumNumberOfIterations: 20 Verbose: 0 Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points positions.size(): 3 Read mesh collection: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz Transforming points Transforming points Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Constructing image-to-world transform from header information (5771302/5771302_tp0_t1_reg.mgz) Read image: 5771302/5771302_tp0_t1_reg.mgz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Constructing image-to-world transform from header information (5771302/5771302_tp1_t1_reg.mgz) Read image: 5771302/5771302_tp1_t1_reg.mgz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Transforming points Transforming points Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Read mesh collection: /opt/aumc-apps-eb/software/FreeSurfer/7.3.2-centos8_x86_64/average/samseg/20Subjects_smoothing2_down2_smoothingForAffine2/atlas_level2.txt.gz Constructing image-to-world transform from header information (5771302/5771302_tp2_t1_reg.mgz) Read image: 5771302/5771302_tp2_t1_reg.mgz maximalDeformation=0.0721 minLogLikelihood=3124909.0761 Total time spent: 0.7836 sec maximalDeformation=0.0347 minLogLikelihood=3124885.1410 Total time spent: 0.7613 sec maximalDeformation=0.0211 minLogLikelihood=3124867.2203 Total time spent: 0.8041 sec maximalDeformation=0.0181 minLogLikelihood=3124848.8032 Total time spent: 0.7688 sec maximalDeformation=0.0298 minLogLikelihood=3124831.6210 Total time spent: 0.7472 sec maximalDeformation=0.0329 minLogLikelihood=3124820.0158 Total time spent: 0.7071 sec maximalDeformation=0.0110 minLogLikelihood=3124812.8403 Total time spent: 0.7124 sec maximalDeformation=0.0000 minLogLikelihood=3124812.8403 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1705 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0173 minLogLikelihood=3124701.3468 Total time spent: 3.4819 sec maximalDeformation=0.0083 minLogLikelihood=3124697.4037 Total time spent: 0.6666 sec maximalDeformation=0.0401 minLogLikelihood=3124687.6729 Total time spent: 0.6817 sec maximalDeformation=0.0049 minLogLikelihood=3124683.8569 Total time spent: 0.7667 sec maximalDeformation=0.0088 minLogLikelihood=3124678.4491 Total time spent: 0.7979 sec maximalDeformation=0.0130 minLogLikelihood=3124673.3347 Total time spent: 0.7163 sec maximalDeformation=0.0091 minLogLikelihood=3124667.3243 Total time spent: 0.6995 sec maximalDeformation=0.0136 minLogLikelihood=3124662.2916 Total time spent: 0.6826 sec maximalDeformation=0.0154 minLogLikelihood=3124656.0611 Total time spent: 0.6820 sec maximalDeformation=0.0210 minLogLikelihood=3124651.0733 Total time spent: 0.6771 sec maximalDeformation=0.0096 minLogLikelihood=3124647.0983 Total time spent: 0.6847 sec maximalDeformation=0.0126 minLogLikelihood=3124641.7690 Total time spent: 0.6883 sec maximalDeformation=0.0089 minLogLikelihood=3124637.0630 Total time spent: 0.6929 sec maximalDeformation=0.0203 minLogLikelihood=3124631.5572 Total time spent: 0.6912 sec maximalDeformation=0.0121 minLogLikelihood=3124626.7278 Total time spent: 0.7152 sec maximalDeformation=0.0107 minLogLikelihood=3124622.7446 Total time spent: 0.7174 sec maximalDeformation=0.0140 minLogLikelihood=3124618.4079 Total time spent: 0.7147 sec maximalDeformation=0.0292 minLogLikelihood=3124615.1492 Total time spent: 0.7310 sec maximalDeformation=0.0106 minLogLikelihood=3124611.5750 Total time spent: 0.7128 sec maximalDeformation=0.0092 minLogLikelihood=3124609.0601 Total time spent: 0.7088 sec maximalDeformation=0.0000 minLogLikelihood=3124609.0601 Total time spent: 0.0000 sec maximalDeformationApplied: 0.0789 ======================================================= ================================= timepointNumber: 1 perVoxelCost: 0.9395036385005009 ================================= ==================== { depth: 1 maximumNumberOfDeformationIterations: 20 absoluteCostPerVoxelDecreaseStopCriterion: 0.0001 verbose: False maximalDeformationStopCriterion: 0.001 lineSearchMaximalDeformationIntervalStopCriterion: 0.001 maximalDeformationAppliedStopCriterion: 0.0 BFGSMaximumMemoryLength: 12 multiResolutionSpecification: { depth: 2 atlasFileName: ../results_samseg_long/5771302/latentAtlases/latentAtlas_iteration_05.mgz targetDownsampledVoxelSpacing: 1.0 maximumNumberOfIterations: 100 estimateBiasField: True } } ==================== iterationNumber: 0 EM converged! maximalDeformation=0.1370 minLogLikelihood=2975921.0242 Total time spent: 2.7719 sec maximalDeformation=0.0602 minLogLikelihood=2975585.5364 Total time spent: 0.6504 sec maximalDeformation=0.0682 minLogLikelihood=2975256.9941 Total time spent: 0.6685 sec maximalDeformation=0.1409 minLogLikelihood=2975109.6901 Total time spent: 0.7230 sec maximalDeformation=0.0414 minLogLikelihood=2974863.6082 Total time spent: 0.7543 sec maximalDeformation=0.0648 minLogLikelihood=2974677.4646 Total time spent: 0.7092 sec maximalDeformation=0.0745 minLogLikelihood=2974585.8621 Total time spent: 0.6952 sec maximalDeformation=0.0183 minLogLikelihood=2974515.0182 Total time spent: 0.7060 sec maximalDeformation=0.0332 minLogLikelihood=2974392.2840 Total time spent: 0.7135 sec maximalDeformation=0.0539 minLogLikelihood=2974319.0087 Total time spent: 0.7182 sec maximalDeformation=0.0928 minLogLikelihood=2974308.4521 Total time spent: 0.7351 sec maximalDeformation=0.0304 minLogLikelihood=2974227.1151 Total time spent: 0.7355 sec maximalDeformation=0.0313 minLogLikelihood=2974178.0126 Total time spent: 0.7448 sec maximalDeformation=0.0492 minLogLikelihood=2974145.9947 Total time spent: 0.7353 sec maximalDeformation=0.0511 minLogLikelihood=2974110.6500 Total time spent: 0.7402 sec maximalDeformation=0.0284 minLogLikelihood=2974075.7891 Total time spent: 0.7403 sec maximalDeformation=0.0167 minLogLikelihood=2974073.8332 Total time spent: 1.3908 sec maximalDeformation=0.0187 minLogLikelihood=2974066.6478 Total time spent: 0.7395 sec maximalDeformation=0.0050 minLogLikelihood=2974063.4920 Total time spent: 2.0576 sec maximalDeformation=0.0124 minLogLikelihood=2974052.7127 Total time spent: 0.7301 sec maximalDeformation=0.0000 minLogLikelihood=2974052.7127 Total time spent: 0.0000 sec maximalDeformationApplied: 0.2190 ======================================================= iterationNumber: 1 EM converged! maximalDeformation=0.0947 minLogLikelihood=2973975.0559 Total time spent: 3.5262 sec maximalDeformation=0.0060 minLogLikelihood=2973969.7636 Total time spent: 0.6903 sec maximalDeformation=0.0393 minLogLikelihood=2973946.9160 Total time spent: 0.7058 sec maximalDeformation=0.0507 minLogLikelihood=2973941.2807 Total time spent: 0.7397 sec maximalDeformation=0.0263 minLogLikelihood=2973929.8905 Total time spent: 0.7515 sec maximalDeformation=0.0243 minLogLikelihood=2973920.5769 Total time spent: 1.4239 sec maximalDeformation=0.0059 minLogLikelihood=2973915.8788 Total time spent: 0.7280 sec maximalDeformation=0.0300 minLogLikelihood=2973898.3617 Total time spent: 0.7284 sec maximalDeformation=0.0295 minLogLikelihood=2973892.7912 Total time spent: 1.4137 sec maximalDeformation=0.0088 minLogLikelihood=2973886.1309 Total time spent: 0.8754 sec maximalDeformation=0.0240 minLogLikelihood=2973872.5757 Total time spent: 0.7126 sec maximalDeformation=0.0140 minLogLikelihood=2973866.6706 Total time spent: 0.7060 sec maximalDeformation=0.0056 minLogLikelihood=2973865.4114 Total time spent: 1.3539 sec maximalDeformation=0.0053 minLogLikelihood=2973861.1408 Total time spent: 0.7228 sec maximalDeformation=0.0076 minLogLikelihood=2973855.4522 Total time spent: 0.7236 sec maximalDeformation=0.0182 minLogLikelihood=2973848.5656 Total time spent: 0.7115 sec maximalDeformation=0.0332 minLogLikelihood=2973840.8040 Total time spent: 0.7119 sec maximalDeformation=0.0237 minLogLikelihood=2973838.3751 Total time spent: 0.7186 sec maximalDeformation=0.0194 minLogLikelihood=2973830.0168 Total time spent: 0.7118 sec maximalDeformation=0.0158 minLogLikelihood=2973823.9415 Total time spent: 0.7124 sec maximalDeformation=0.0000 minLogLikelihood=2973823.9415 Total time spent: 0.0000 sec maximalDeformationApplied: 0.1366 ======================================================= ================================= timepointNumber: 2 perVoxelCost: 0.9061403042173475 ================================= **************************************************************************************************** iterationNumber: 4 totalCost: 12751190.210887475 latentAtlasCost: 253118.92158179975 totalTimepointCost: 12498071.289305676 **************************************************************************************************** Stopping using default intracranial structures to compute sbtiv measure using default intracranial structures to compute sbtiv measure using default intracranial structures to compute sbtiv measure run_samseg_long complete: 0:33:44.540682