Dear Freesurfer Team,

Thank you for your work on the segmentation and analysis tools that have been provided through Freesurfer and that have been used so widely. We are wondering if there is a T1 image data set available for which manual delineation of the boundaries of the hippocampal subfield summation has been performed, and whether the images and masks might be available for DICE comparison to the masks and volume produced by FS in users’ hands? We note that the subfield summation does not include the alveus and therefore direct comparison to masks generated using standard manual hippocampal segmentation protocols is not straightforward.

With thanks and best regards,

Dawn Matthews

Dawn C. Matthews

CEO, ADM Diagnostics, Inc.

555 Skokie Blvd., Suite 500

Northbrook, Illinois  60062

dmatthews@admdx.com