Hi Sean

If you can load the 3D VBM data into Matlab as a matrix Y(nm x nv, nm total number of VBM maps and nv total number of voxels) then you can use lme_mass_fit_vw to fit a voxel-wise lme model (the region-wise approach is not yet implemented for euclidean 3D data).

You should ask to the list but I think there should be a way to stack all your VBM maps into a single .mgh file. For 2D surface data that can be accomplished with mris_preproc but I don't know if you can use it with volumetric data. Once you have your data in a single .mgh file you can read it into Matlab using the lme toolbox's fs_read_Y function as explained in the wiki and perform your analyses.

Best

-Jorge

De: Seán Froudist Walsh <froudiss@tcd.ie>
Para: freesurfer@nmr.mgh.harvard.edu
Enviado: Lunes 23 de septiembre de 2013 13:54
Asunto: [Freesurfer] LME toolbox for VBM-style data?

Dear FreeSurfers,

I was wondering if anyone had tried to use the MATLAB LME toolbox that you kindly developed for volume based VBM-style data? Either way would you be able to impart some initial advice as to considerations that should be made etc?

Best wishes and many thanks,

Sean

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